Human GEM cDNA Clone Expression Plasmid – Cat# MBS1265634

GEM cDNA Clone – GTP Binding Protein Overexpressed in Skeletal Muscle (Human)

Name: GEM cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1265634
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1265634

MBS1265634 is a cDNA clone targeting GEM. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GEM, cDNA Clone

Full Product Name

GEM cDNA Clone

Product Gene Name

GEM cdna clone

Sequence

atgactctga ataatgtcac catgcgccag ggcactgtgg gcatgcagcc acagcagcag cgctggagca tcccagctga tggcaggcat ctgatggtcc agaaagagcc ccaccagtac agccaccgca accgccattc tgctacccct gaggaccact gccgccgaag ctggtcctct gactccacag actcagtcat ctcctctgag tcagggaaca cctactaccg agtggtgctc ataggggagc agggggtggg caagtccact ctggccaaca tctttgcagg tgtgcatgac agcatggaca gcgactgcga ggtgctggga gaagatacat atgaacgaac cctgatggtt gatggggaaa gtgcaacgat tatactcctg gatatgtggg aaaataaggg ggaaaatgaa tggctccatg accactgcat gcaggtcggg gacgcatacc tgattgtcta ctcaatcaca gaccgagcga gcttcgagaa ggcatctgag ctgcgaatcc agctccgcag ggcccggcag acagaggaca ttcccataat tttggttggc aacaaaagtg acttagtgcg gtgccgagaa gtgtctgtat cagaagggag agcctgtgca gtggtgtttg actgcaagtt catcgagacc tctgcagctg tccagcacaa cgtgaaggag ctgtttgagg gcattgtgcg acaggtgcgc cttcggcggg acagcaagga gaagaatgaa cggcggctgg cctaccagaa aaggaaggag agcatgccca ggaaagccag gcgcttctgg ggcaagatcg tggccaaaaa caacaagaat atggccttca agctcaagtc caaatcctgc catgacctct ctgtactcta g

Molecular Weight

33,949 Da

OMIM

600164

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GEM cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GEM. It may not necessarily be applicable to this product.

NCBI GI #

34193982

NCBI GeneID

2669

NCBI Accession #

BC022010

UniProt Secondary Accession #

B2RA31

UniProt Related Accession #

P55040

NCBI Official Full Name

Homo sapiens GTP binding protein overexpressed in skeletal muscle, mRNA

NCBI Official Synonym Full Names

GTP binding protein overexpressed in skeletal muscle

NCBI Official Symbol

GEM

NCBI Official Synonym Symbols

KIR

UniProt Protein Name

GTP-binding protein GEM

UniProt Synonym Protein Names

GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR

Protein Family

GLABRA2 expression modulator

UniProt Gene Name

GEM

UniProt Synonym Gene Names

KIR

UniProt Entry Name

GEM_HUMAN

NCBI Protein Information

GTP-binding protein GEM

NCBI Summary for GEM

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for GEM

GEM: Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Belongs to the small GTPase superfamily. RGK family.

Protein type: G protein, monomeric, RGK; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 8q13-q21

Cellular Component: internal side of plasma membrane; midbody; spindle midzone

Molecular Function: GDP binding; GTP binding; GTPase activity; magnesium ion binding; protein binding

Biological Process: cell surface receptor linked signal transduction; chromosome organization and biogenesis; immune response; metaphase plate congression; mitosis; signal transduction

Research Articles on GEM

1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with GEM cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>825 publications with GEM and Neoplasms
Drug Toxicity Antibodies	>238 publications with GEM and Drug Toxicity
Lung Neoplasms Antibodies	>150 publications with GEM and Lung Neoplasms
Lung Diseases Antibodies	>143 publications with GEM and Lung Diseases
Neutropenia Antibodies	>117 publications with GEM and Neutropenia
Cardiovascular Diseases Antibodies	>101 publications with GEM and Cardiovascular Diseases
Liver Neoplasms Antibodies	>100 publications with GEM and Liver Neoplasms
Nervous System Diseases Antibodies	>93 publications with GEM and Nervous System Diseases
Gastrointestinal Diseases Antibodies	>90 publications with GEM and Gastrointestinal Diseases
Neoplasms, Experimental Antibodies	>89 publications with GEM and Neoplasms, Experimental

Organs/Tissues associated with GEM cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>323 publications with GEM and Blood
Lung Antibodies	>186 publications with GEM and Lung
Liver Antibodies	>176 publications with GEM and Liver
Brain Antibodies	>82 publications with GEM and Brain
Bone Antibodies	>72 publications with GEM and Bone
Pancreas Antibodies	>69 publications with GEM and Pancreas
Muscle Antibodies	>62 publications with GEM and Muscle
Vascular Antibodies	>62 publications with GEM and Vascular
Heart Antibodies	>50 publications with GEM and Heart
Skin Antibodies	>49 publications with GEM and Skin