Human GEMIN5 cDNA Clone Expression Plasmid – Cat# MBS1272031

GEMIN5 cDNA Clone – Gem (Nuclear Organelle) Associated Protein 5 (Human)

Name: GEMIN5 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272031
Price: 2115 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272031

MBS1272031 is a cDNA clone targeting GEMIN5. More details

$2115 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GEMIN5, cDNA Clone

Full Product Name

GEMIN5 cDNA Clone

Product Gene Name

GEMIN5 cdna clone

Sequence

atggggcagg agccgcggac gctgccgccc tcccccaact ggtactgcgc ccgctgcagc gatgccgtgc ccgggggcct ctttggcttc gccgcgcgga cctccgtctt ccttgtccgc gtgggcccgg gcgcaggcga gagtccaggg acacccccgt ttcgagtcat aggagagttg gtgggacaca ccgaaagggt ctctggcttc acattttctc atcaccctgg tcagtacaac ctctgtgcca ccagctccga cgatgggact gtgaaaatat gggatgtaga gacaaaaaca gttgtgacag aacatgcact ccatcagcat acgatatcaa cattacattg gtctcctcga gtaaaggact taatagtatc tggggatgaa aaaggagtag ttttctgtta ctggtttaac agaaatgaca gccagcacct ctttatagaa cccaggacaa ttttctgtct tacttgttca cctcatcatg aagatttagt agccattggc tacaaggatg gcatagtggt gataattgac atcagtaaga aaggagaagt tattcatagg cttcgaggcc atgatgatga aatccactcc atagcctggt gtcccctgcc tggtgaagat tgtttatcta taaaccaaga ggaaacttca gaagaagctg aaattaccaa cgggaatgct gtagcacaag ctccagtaac aaaaggttgc tacttagcca ctggaagcaa agatcaaacc attcgaatct ggagctgttc tagaggccga ggggtgatga ttttgaaatt gccctttctg aagagaagag gagggggtat agacccaact gttaaagagc gcctttggtt gacactccat tggcccagca atcaaccaac acagctggta tctagctgtt ttggaggtga actgttgcaa tgggatctca ctcaatcttg gagacggaaa tacaccctct tcagtgcctc atcagaaggg caaaatcatt caagaattgt gtttaattta tgtcctttac aaacagagga tgacaaacag ctgttacttt ctacatcaat ggatagagat gtaaaatgtt gggacatagc caccttggag tgcagctgga cccttccttc ccttggtggg tttgcataca gcctggcttt ctcttctgtg gacataggct ctttggccat aggtgttggg gatggcatga tccgtgtatg gaatacactc tccataaaga acaactatga tgtgaaaaat ttttggcaag gcgtgaagtc caaggttaca gcgctgtgct ggcacccaac caaggaaggt tgcttagctt ttggaactga tgatggaaaa gtgggattgt atgacaccta ctccaacaag cctccacaga tttctagcac atatcataag aagactgtat atacgttagc ctgggggcca ccagtacccc ccatgtcact tggaggagaa ggagacagac cttcccttgc tttatacagc tgtggaggag aagggattgt cttacagcat aatccctgga agcttagtgg agaagccttt gacatcaaca aactcatcag ggacaccaat tcaatcaaat acaaattgcc tgtacacaca gagataagtt ggaaagcaga tggcaaaatc atggctcttg gcaatgaaga tggatcaata gaaatatttc agattcccaa cctgaaactg atctgtacta tccaacagca tcacaagctt gtgaatacca ttagctggca tcatgagcat ggcagccagc cagaattgag ctatctgatg gcctctggct ccaacaatgc agtcatttac gtgcacaacc tgaagactgt catagagagc agccctgagt ctccagtgac cattacagag ccctaccgga ccctctcagg gcatacggcc aagattacca gtgtggcgtg gagcccacat catgatggaa ggctggtatc tgcttcctat gatggtacag cccaggtgtg ggatgctctc cgggaagagc ccctgtgcaa tttccgagga catcaaggtc gactgctttg tgtggcatgg tctcctttgg atccagactg catctattca ggggcagatg acttttgtgt gcacaagtgg ctcacttcca tgcaagatca ttcccggcct cctcaaggca aaaaaagtat tgaattggag aaaaaacggc tctctcaacc taaggcaaag cccaaaaaga agaaaaagcc caccttgaga actcctgtaa agctggaatc gattgatgga aatgaagaag aaagcatgaa ggagaactca ggacctgttg agaatggtgt gtcagaccaa gaaggggagg agcaagcacg ggagccggaa ttaccctgtg gccttgctcc agcggtttct agagaaccag ttatctgcac tccagtttcc tcaggctttg aaaagtcaaa agtcaccatt aataacaaag tcattttact gaaaaaggag ccaccaaaag agaagccaga aaccttaatc aagaagagaa aagctcgttc cttgcttccc ctgagtacaa gcctggacca cagatccaaa gaggagcttc atcaggactg tttggtacta gcaactgcaa agcactccag agagctgaat gaagatgtgt ctgctgatgt tgaggaaaga tttcatctgg ggcttttcac agacagggct accctgtata gaatgattga tattgaagga aaaggtcact tagaaaatgg ccaccctgag ttatttcacc agcttatgct ttggaaagga gatctcaaag gtgttctcca gactgcagca gaaagagggg agctgacaga caaccttgtg gctatggcac cagcagctgg ctaccatgtg tggctatggg ctgtggaagc ttttgccaaa cagctgtgtt ttcaggatca gtatgtcaag gctgcttctc acctactttc catccacaaa gtgtatgaag cggtggagct gctcaagtca aaccattttt acagggaagc tattgcgatt gccaaggccc ggctgcgccc ggaggaccca gtcctgaagg acttgtacct cagctgggga accgtcctag aaagagatgg ccactatgct gtagctgcca aatgctattt aggggccact tgtgcttatg atgcagccaa agttttggcc aaaaaggggg atgcggcatc acttagaacg gctgcagagt tggctgccat cgtaggagag gatgagttgt ctgcttccct ggctctcaga tgtgcccaag agctgcttct ggccaacaac tgggtgggag cccaggaagc cctgcagctg catgaaagtc tacagggtca gagattggtg ttttgccttc tggagctact gtccaggcat ctggaggaaa agcagctttc agagggcaaa agctcctcct cttaccacac ttggaacacg ggcaccgaag ggcctttcgt ggagagggtg actgcagtgt ggaagagcat cttcagcctt gacacccctg agcagtatca ggaagccttt cagaagctgc agaacatcaa gtacccatct gctacaaata acacacctgc caaacagctc ctgcttcaca tttgccatga cttgaccctg gcagtgctga gccaacagat ggcctcctgg gacgaggctg tgcaggcgct ccttcgggcg gtggtccgga gctatgactc agggagcttc accatcatgc aggaagtgta ctcagccttt ctccctgatg gctgtgacca cctaagagac aagttggggg accatcaatc ccctgccaca ccagctttca aaagtttgga ggcctttttt ctttatgggc gtctgtatga attctggtgg tctctctcca gaccttgccc aaattccagt gtctgggtaa gggctggtca cagaacactc tctgttgagc caagccagca gttagacact gccagcactg aagaaacgga ccctgaaact tctcagccag agccaaacag gccttcagaa ctagacttga gactcacaga agaaggtgag cgaatgctga gtacttttaa ggagctcttt tcagaaaagc atgccagtct ccaaaactca cagagaactg ttgctgaagt ccaagagacc ttggcagaaa tgatccgaca acaccaaaag agtcaactct gtaaatccac agcaaatggt cctgataaga atgaaccgga agtagaagca gagcagcccc tctgcagttc tcagagccag tgtaaagaag aaaaaaatga gccactttct ctgcctgagt taaccaaaag gcttaccgag gcaaatcaga gaatggcaaa atttcctgag agcattaagg cctggccctt cccagatgtg ctggagtgct gcctcgtcct gcttctcatc aggtcccact ttcctggctg tctggcccag gaaatgcagc agcaggccca agagctcctt cagaaatacg gcaacacgaa aacttacaga agacactgcc agaccttctg tatgtga

Molecular Weight

168,589 Da

OMIM

607005

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GEMIN5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GEMIN5. It may not necessarily be applicable to this product.

NCBI GI #

109731761

NCBI GeneID

25929

NCBI Accession #

BC113614

UniProt Secondary Accession #

Q14CV0; Q8WWV4; Q969W4; Q9H9K3; Q9UFI5

UniProt Related Accession #

Q8TEQ6

NCBI Official Full Name

Homo sapiens gem (nuclear organelle) associated protein 5, mRNA

NCBI Official Synonym Full Names

gem nuclear organelle associated protein 5

NCBI Official Symbol

GEMIN5

NCBI Official Synonym Symbols

GEMIN-5

UniProt Protein Name

Gem-associated protein 5

Protein Family

Component of gems protein

UniProt Gene Name

GEMIN5

UniProt Synonym Gene Names

Gemin5

UniProt Entry Name

GEMI5_HUMAN

NCBI Protein Information

gem-associated protein 5

NCBI Summary for GEMIN5

This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

UniProt Comments for GEMIN5

GEMIN5: the snRNA-binding protein of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.

Protein type: RNA-binding; Nuclear receptor co-regulator; RNA processing; RNA splicing

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: cytoplasm; cytosol; membrane; nuclear body; nucleoplasm; nucleus; SMN complex

Molecular Function: protein binding; snRNA binding

Biological Process: nuclear import; nuclear mRNA splicing, via spliceosome; protein complex assembly; spliceosomal snRNP biogenesis

Research Articles on GEMIN5

1. Gemin5 is dispensable for snRNA identification and snRNP assembly.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GEMIN5 cdna clone

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Of Non-coding RNA Pathway antibodies	Metabolism Of Non-coding RNA Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
Survival Motor Neuron (SMN) Complex Pathway antibodies	Survival Motor Neuron (SMN) Complex Pathway Diagram
SnRNP Assembly Pathway antibodies	SnRNP Assembly Pathway Diagram

Diseases associated with GEMIN5 cdna clone

Disease Name	Pubmed Publications
Atrophy Antibodies	>12 publications with GEMIN5 and Atrophy
Neoplasm Metastasis Antibodies	>2 publications with GEMIN5 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>1 publications with GEMIN5 and Breast Neoplasms
Necrosis Antibodies	>1 publications with GEMIN5 and Necrosis

Organs/Tissues associated with GEMIN5 cdna clone

Organ/Tissue Name	Pubmed Publications
Mouth Antibodies	>3 publications with GEMIN5 and Mouth
Kidney Antibodies	>1 publications with GEMIN5 and Kidney
Uncharacterized Tissue Antibodies	>1 publications with GEMIN5 and Uncharacterized Tissue
Brain Antibodies	>1 publications with GEMIN5 and Brain