Human GLRX3 cDNA Clone Expression Plasmid – Cat# MBS1272177

GLRX3 cDNA Clone – Glutaredoxin 3 (Human)

Name: GLRX3 cDNA Clone; Glutaredoxin 3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272177
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272177

MBS1272177 is a cDNA clone targeting GLRX3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GLRX3, cDNA Clone

Full Product Name

GLRX3 cDNA Clone

Product Gene Name

GLRX3 cdna clone

Sequence

atggcggcgg gggcggctga ggcagctgta gcggccgtgg aggaggtcgg ctcagccggg cagtttgagg agctgctgcg cctcaaagcc aagtccctcc ttgtggtcca tttctgggca ccatgggctc cacagtgtgc acagatgaac gaagttatgg cagagttagc taaagaactc cctcaagttt catttgtgaa gttggaagct gaaggtgttc ctgaagtatc tgaaaaatat gaaattagct ctgttcccac ttttctgttt ttcaagaatt ctcagaaaat cgaccgatta gatggtgcac atgccccaga gttgaccaaa aaagttcagc gacatgcatc tagtggctcc ttcctaccca gcgctaatga acatcttaaa gaagatctca accttcgctt gaagaaattg actcatgctg ccccctgcat gctgtttatg aaaggaactc ctcaagaacc acgctgtggt ttcagcaagc agatggtgga aattcttcac aaacataata ttcagtttag cagttttgat atcttctcag atgaagaggt tcgacaggga ctcaaagcct attccagttg gcctacctat cctcagctct atgtttctgg agagctcata ggaggacttg atataattaa ggagctagaa gcatctgaag aactagatac aatttgtccc aaagctccca aattagagga aaggctcaaa gtgctgacaa ataaagcttc tgtgatgctc tttatgaaag gaaacaaaca ggaagcaaaa tgtggattca gcaaacaaat tctggaaata ctaaatagta ctggtgttga atatgaaaca ttcgatatat tggaggatga agaagttcgg caaggattaa aagcttactc aaattggcca acataccctc agctgtatgt gaaaggggag ctggtgggag gattggatat tgtgaaggaa ctgaaagaaa atggtgaatt gctgcctata ctgagaggag aaaattaa

Molecular Weight

37,432 Da

OMIM

612754

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GLRX3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLRX3. It may not necessarily be applicable to this product.

NCBI GI #

13528998

NCBI GeneID

10539

NCBI Accession #

BC005289

UniProt Secondary Accession #

Q5JV01; Q96CE0; Q9P1B0; Q9P1B1; B3KMP7; B3KMQ5; D3DRG2

UniProt Related Accession #

O76003

NCBI Official Full Name

Homo sapiens glutaredoxin 3, mRNA

NCBI Official Synonym Full Names

glutaredoxin 3

NCBI Official Symbol

GLRX3

NCBI Official Synonym Symbols

GRX3; GRX4; GLRX4; PICOT; TXNL2; TXNL3

UniProt Protein Name

Glutaredoxin-3

UniProt Synonym Protein Names

PKC-interacting cousin of thioredoxin; PICOT; PKC-theta-interacting protein; PKCq-interacting protein; Thioredoxin-like protein 2

Protein Family

Glutaredoxin

UniProt Gene Name

GLRX3

UniProt Synonym Gene Names

PICOT; TXNL2; PICOT; PKCq-interacting protein

UniProt Entry Name

GLRX3_HUMAN

NCBI Protein Information

glutaredoxin-3

NCBI Summary for GLRX3

This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for GLRX3

GLRX3: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 10q26

Molecular Function: protein binding

Biological Process: regulation of the force of heart contraction

Research Articles on GLRX3

1. findings provide novel insights into the regulation of Grx3, which is crucial for cell survival against environmental insults

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with GLRX3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with GLRX3 and Neoplasms
Hypertrophy Antibodies	>3 publications with GLRX3 and Hypertrophy
Lung Neoplasms Antibodies	>2 publications with GLRX3 and Lung Neoplasms
Heart Diseases Antibodies	>1 publications with GLRX3 and Heart Diseases
Cardiovascular Diseases Antibodies	>1 publications with GLRX3 and Cardiovascular Diseases
Kidney Neoplasms Antibodies	>1 publications with GLRX3 and Kidney Neoplasms
Abnormalities, Drug-Induced Antibodies	>1 publications with GLRX3 and Abnormalities, Drug-Induced
Neoplasm Metastasis Antibodies	>1 publications with GLRX3 and Neoplasm Metastasis
Liver Neoplasms Antibodies	>1 publications with GLRX3 and Liver Neoplasms
Cardiomegaly Antibodies	>1 publications with GLRX3 and Cardiomegaly

Organs/Tissues associated with GLRX3 cdna clone

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>3 publications with GLRX3 and Lung
Blood Antibodies	>3 publications with GLRX3 and Blood
Brain Antibodies	>3 publications with GLRX3 and Brain
Kidney Antibodies	>2 publications with GLRX3 and Kidney
Muscle Antibodies	>1 publications with GLRX3 and Muscle
Pancreas Antibodies	>1 publications with GLRX3 and Pancreas
Liver Antibodies	>1 publications with GLRX3 and Liver
Lymph Antibodies	>1 publications with GLRX3 and Lymph
Bladder Antibodies	>1 publications with GLRX3 and Bladder
Embryonic Tissue Antibodies	>1 publications with GLRX3 and Embryonic Tissue