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GMIP cDNA Clone – GEM Interacting Protein (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269172

MBS1269172 is a cDNA clone targeting GMIP. More details

$1075 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GMIP, cDNA Clone
Full Product Name
GMIP cDNA Clone
Product Gene Name
GMIP cdna clone
Sequence
atggacgcag cagagccggg actcccccca ggtcctgagg gcaggaagag gtacagtgac atcttccgga gcctggacaa cctcgaaatc tcactgggga acgtgaccct tgagatgctg gctggagacc ctctactctc agaagaccca gaacctgaca agacccctac agccactgtt accaacgaag ccagctgttg gagcggcccc tccccagagg gtcctgtacc cctcacaggg gaggaactgg acttgcggct cattcggaca aaggggggtg tggacgcagc cctggaatat gccaagacct ggagccgcta tgccaaggaa ctgcttgcct ggactgaaaa gagagccagc tatgagctgg agtttgctaa gagcaccatg aagatcgctg aagctggcaa ggtgtccatt caacagcaga gccacatgcc tctgcagtac atctacaccc tgtttctgga gcacgatctc agcctgggaa ccctggccat ggagacagtg gcccagcaga aaagagacta ctaccagccc ctcgccgcca aacggactga gattgagaag tggcggaagg agttcaagga gcagtggatg aaggagcaga agcggatgaa tgaggcggtg caggcactgc ggcgcgccca gctgcagtat gtgcaacgca gcgaggacct gcgggcacgc tcccaggggt cccctgagga ctcggccccc caggcctcgc cgggacctag caagcagcag gagcggcggc ggcgctcgcg agaggaggcc caggccaagg cgcaggaggc cgaggcgctg taccaggcct gtgtccgcga ggccaacgcg cggcagcagg acctggagat cgccaagcag cgaatcgtgt cgcacgtgcg caagctggtg tttcaggggg atgaagtgct gaggcgggtg acgctgagtc tcttcgggct gcggggggcg caggcagagc gtggcccccg cgccttcgcc gccctggccg agtgctgtgc gccctttgag ccgggccagc gctaccagga gtttgtacgg gcgctgcggc ccgaggcccc gccgcccccg ccgcccgcct tctccttcca ggagttcctt ccctccttga acagctcccc tctggacatc agaaagaagc tctctgggcc tcttcctcca aggctggatg agaattcagc tgagccaggc ccttgggagg atccgggcac aggctggcgc tggcaaggga ctccaggccc cactccgggc agcgatgtgg acagcgtggg tggcggcagc gagtctcggt ccctggactc acccacttcc agcccaggcg ctggcacgag gcagctggtg aaggcttcgt ccacaggcac tgagtcctca gatgactttg aggagcgaga ccctgacctg ggagacgggc tggagaatgg gctgggcagc cccttcggga agtggacact gtccagcgcg gctcagaccc accagctgcg gcgactgcgg ggcccagcca agtgccgcga gtgcgaagcc ttcatggtca gcgggacgga gtgtgaggag tgctttctga cctgccacaa gcgctgcctg gagactctcc tgatcctctg tggacacagg cggctcccag cccggacacc cctttttggg gttgacttcc tgcagctacc cagggacttc ccggaggagg taccctttgt ggtcacgaag tgcacggctg agatagaaca ccgtgccctg gatgtgcagg gcatttaccg ggtcagcggg tcccgggtcc gtgtggagcg gctgtgccag gctttcgaga atggccgagc gttggtggag ctgtcgggga actcgcctca tgacgtctcg agtgtcctca agcgatttct tcaggagctc accgagcccg tgatcccctt ccacctctac gacgccttca tctctctggc taagaccttg catgcagacc ctggggacga ccctgggacc cccagcccca gccctgaggt tatccgctcg ctgaagaccc tcttggtaca gctgcctgac tctaactaca acaccctgcg gcacctggtg gcccatctgt tcagggtggc tgcacgattt atggaaaaca agatgtctgc caacaacctg ggcattgtgt ttgggccgac actgctgcgg ccgccggacg gcccgcgggc agccagcgcc atccctgtca cctgcctgct ggactctggg catcaggccc agcttgtgga gttcctcatc gtgcactacg agcagatctt tgggatggat gagctccccc aggccactga gcccccgccc caagactcca gcccagcccc tgggcccctc acaaccagct cccaaccgcc acccccgcac cttgacccag actcccagcc cccagtccta gcctcagacc ccggcccaga cccccagcac cacagtaccc tggagcagca tcccacggcc acacctaccg agattccaac tccacagagt gaccagagag aggacgtggc tgaagacacc aaagatgggg gaggggaagt gtccagccaa ggcccagagg actcactcct ggggacacag tctcgtggcc acttcagccg ccagccagtg aagtatcccc ggggcggtgt gaggcctgta acccaccagc tgtccagtct ggccctggtg gcttccaagc tgtgcgagga gacccccatc acatcagtgc ccagagggag tttgcggggg cgggggccca gccctgcagc tgcctcccct gagggcagcc ccctgcgccg caccccgctg cccaagcatt ttgagattac ccaggagaca gcccggctac tctcgaaatt ggacagcgag gctgtgccca gggccacctg ctgcccggac gtccagcctg aggaagccga ggaccatctc tga
Molecular Weight
103,960 Da
OMIM
609694
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GMIP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GMIP. It may not necessarily be applicable to this product.

NCBI GI #
116496744
NCBI GeneID
51291
NCBI Accession #
BC126436
UniProt Secondary Accession #
A0AVN9; B7ZLZ0
UniProt Related Accession #
Q9P107
NCBI Official Full Name
Homo sapiens GEM interacting protein, mRNA
NCBI Official Synonym Full Names
GEM interacting protein
NCBI Official Symbol
GMIP
NCBI Official Synonym Symbols
ARHGAP46
UniProt Protein Name
GEM-interacting protein
Protein Family
GEM-interacting protein
UniProt Gene Name
GMIP
UniProt Synonym Gene Names
GMIP
UniProt Entry Name
GMIP_HUMAN
NCBI Protein Information
GEM-interacting protein

NCBI Summary for GMIP

This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for GMIP

GMIP: Stimulates, in vitro and in vivo, the GTPase activity of RhoA.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: cytosol; intracellular

Molecular Function: GTPase activator activity; protein binding

Biological Process: positive regulation of defense response to virus by host; regulation of small GTPase mediated signal transduction
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Research Articles on GMIP

1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GMIP cdna clone

 Products by Pathway  Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with GMIP cdna clone

 Disease Name  Pubmed Publications
 Abnormalities, Multiple Antibodies  >1 publications with GMIP and Abnormalities, Multiple

Organs/Tissues associated with GMIP cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with GMIP and Brain
 Blood Antibodies  >2 publications with GMIP and Blood
 Vascular Antibodies  >1 publications with GMIP and Vascular
 Spleen Antibodies  >1 publications with GMIP and Spleen
 Kidney Antibodies  >1 publications with GMIP and Kidney
 Heart Antibodies  >1 publications with GMIP and Heart
 Lung Antibodies  >1 publications with GMIP and Lung
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