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GNB1L cDNA Clone – Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 1-Like (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276046

MBS1276046 is a cDNA clone targeting GNB1L. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNB1L, cDNA Clone
Full Product Name
GNB1L cDNA Clone
Product Gene Name
GNB1L cdna clone
Sequence
atgacggccc cctgcccgcc gccacctcca gacccccagt ttgtcctccg aggcacccag tcaccggtgc atgcgctgca cttctgcgaa ggagcccagg ctcaggggcg cccgctcctc ttctcagggt ctcagagtgg cctggtacac atctggagcc tgcagacgcg gagagcggtt accaccctgg atggccacgg cggccagtgt gtgacctggc tgcagacgct gccccagggg cgccagctcc tcagtcaggg ccgggacctg aagctgtgcc tgtgggacct cgcggagggc aggagcgctg tcgtggactc cgtgtgcttg gagagtgtgg gcttctgccg gagcagcatc ctggccgggg gccagccacg ctggacgctt gccgtgccag ggaggggcag cgacgaggtt cagattctgg agatgccctc caagacgtca gtgtgcgccc tgaagccgaa ggcagatgcc aagctgggca tgcccatgtg cctgcggctg tggcaggccg actgcagctc ccgcccactc cttctggccg gctatgagga tggatcggtg gtcctgtggg acgtctctga gcagaaggtg tgcagccgca tcgcctgcca tgaggagccc gtcatggacc ttgactttga ctcccagaag gccaggggca tctcaggctc cgcggggaag gcgctggctg tctggagcct ggactggcag caggccctgc aggtgcgtgg gactcatgaa ctcaccaatc ccgggatcgc cgaggtcacg atccggccag atcgcaagat cctggccacc gcaggctggg accaccgcat ccgcgtgttc cactggcgga cgatgcagcc actggccgtg ctggccttcc acagcgccgc tgtccagtgc gtggccttca ccgccgatgg cttgctggcc gcgggctcca aggatcagcg gatcagcctc tggtcactct acccacgcgc atga
Molecular Weight
22,896 Da
OMIM
610778
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GNB1L cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GNB1L. It may not necessarily be applicable to this product.

NCBI GI #
15082308
NCBI GeneID
54584
NCBI Accession #
BC012060
UniProt Secondary Accession #
Q9H2S2; Q9H4M4
UniProt Related Accession #
Q9BYB4
NCBI Official Full Name
Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1-like, mRNA
NCBI Official Synonym Full Names
G protein subunit beta 1 like
NCBI Official Symbol
GNB1L
NCBI Official Synonym Symbols
GY2; FKSG1; WDR14; WDVCF; DGCRK3
UniProt Protein Name
Guanine nucleotide-binding protein subunit beta-like protein 1
UniProt Synonym Protein Names
DGCRK3; WD repeat-containing protein 14; WD40 repeat-containing protein deleted in VCFS; WDVCF
Protein Family
Guanine nucleotide-binding protein subunit beta-like protein
UniProt Gene Name
GNB1L
UniProt Synonym Gene Names
GY2; KIAA1645; WDR14; G protein subunit beta-like protein 1; WDVCF
UniProt Entry Name
GNB1L_HUMAN
NCBI Protein Information
guanine nucleotide-binding protein subunit beta-like protein 1

NCBI Summary for GNB1L

This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GNB1L

GNB1L: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 22q11.2

Research Articles on GNB1L

1. mRNA expression results implies that the GNB1L high-expression allele is the risk allele for schizophrenia and bipolar disorder in the Han Chinese population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with GNB1L cdna clone

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with GNB1L and Congenital Abnormalities
 Heart Defects, Congenital Antibodies  >6 publications with GNB1L and Heart Defects, Congenital
 Abnormalities, Multiple Antibodies  >5 publications with GNB1L and Abnormalities, Multiple
 Craniofacial Abnormalities Antibodies  >5 publications with GNB1L and Craniofacial Abnormalities
 Carcinoma, Hepatocellular Antibodies  >1 publications with GNB1L and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with GNB1L and Liver Neoplasms
 Carcinoma Antibodies  >1 publications with GNB1L and Carcinoma
 Neoplasms Antibodies  >1 publications with GNB1L and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with GNB1L and Nervous System Diseases

Organs/Tissues associated with GNB1L cdna clone

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >3 publications with GNB1L and Heart
 Ear Antibodies  >2 publications with GNB1L and Ear
 Thymus Antibodies  >2 publications with GNB1L and Thymus
 Blood Antibodies  >2 publications with GNB1L and Blood
 Embryonic Tissue Antibodies  >2 publications with GNB1L and Embryonic Tissue
 Brain Antibodies  >2 publications with GNB1L and Brain
 Muscle Antibodies  >1 publications with GNB1L and Muscle
 Eye Antibodies  >1 publications with GNB1L and Eye
 Liver Antibodies  >1 publications with GNB1L and Liver
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