Human GPAA1 cDNA Clone Expression Plasmid – Cat# MBS1265963

GPAA1 cDNA Clone – Glycosylphosphatidylinositol Anchor Attachment Protein 1 Homolog (Yeast) (Human)

Name: GPAA1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1265963
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1265963

MBS1265963 is a cDNA clone targeting GPAA1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPAA1, cDNA Clone

Full Product Name

GPAA1 cDNA Clone

Product Gene Name

GPAA1 cdna clone

Sequence

atgggcctcc tgtcggaccc ggttcgccgg cgcgcgctcg cccgcctagt gctgcgcctc aacgcgccgt tgtgcgtgct gagctacgtg gcgggcatcg cctggttctt ggcgctggtt ttcccgccgc tgacccagcg cacttacatg tcggagaacg ccatgggctc caccatggtg gaggagcagt ttgcgggcgg agaccgtgcc cgggcttttg cccgggactt cgccgcccac cgcaagaagt cgggggctct gccagtggcc tggcttgaac ggacgatgcg gtcagtaggg ctggaggtct acacgcagag tttctcccgg aaactgccct tcccagatga gacccacgag cgctatatgg tgtcgggcac caacgtgtac ggcatcctgc gggccccgcg tgctgccagc accgagtcgc ttgtgctcac cgtgccctgt ggctctgact ctaccaacag ccaggctgtg gggctgctgc tggcactggc tgcccacttc cgggggcaga tttattgggc caaagatatc gtcttcctgg taacagaaca tgaccttctg ggcactgagg cttggcttga agcctaccac gatgtcaatg tcactggcat gcagtcgtct cccctgcagg gccgagctgg ggccattcag gcagccgtgg ccctggagct gagcagtgat gtggtcacca gcctcgatgt ggccgtggag gggcttaacg ggcagctgcc caaccttgac ctgctcaatc tcttccagac cttctgccag aaagggggcc tgttgtgcac gcttcagggc aagctgcagc ccgaggactg gacatcattg gatggaccgc tgcagggcct gcagacactg ctgctcatgg ttctgcggca ggcctccggc cgcccccacg gctcccatgg cctcttcctg cgctaccgtg tggaggccct aaccctgcgt ggcatcaata gcttccgcca gtacaagtat gacctggtgg cagtgggcaa ggctttggag ggcatgttcc gcaagctcaa ccacctcctg gagcgcctgc accagtcctt cttcctctac ttgctccccg gcctctcccg cttcgtctcc atcggcctct acatgcccgc tgtcggcttc ttgctcctgg tccttggtct caaggctctg gaactgtgga tgcagctgca tgaggctgga atgggccttg aggagcccgg gggtgcccct ggccccagtg taccccttcc cccatcacag ggtgtggggc tggcctcgct cgtggcacct ctgctgatct cacaggccat gggactggcc ctctatgtcc tgccagtgct gggccaacac gttgccaccc agcacttccc agtggcagag gctgaggctg tggtgctgac actgctggcg atttatgcag ctggcctggc cctgccccac aatacccacc gggtggtaag cacacaggcc ccagacaggg gctggatggc actgaagctg gtagccctga tctacctagc actgcagctg ggctgcatcg ccctcaccaa cttctcactg ggcttcctgc tggccaccac catggtgccc actgctgcgc ttgccaagcc tcatgggccc cggaccctct atgctgccct gctggtgctg accagcccgg cagccacgct ccttggcagc ctgttcctgt ggcgggagct gcaggaggcg ccactgtcac tggccgaggg ctggcagctc ttcctggcag cgctagccca gggtgtgctg gagcaccaca cctacggcgc cctgctcttc ccactgctgt ccctgggcct ctacccctgc tggctgcttt tctggaatgt gctcttctgg aagtga

Molecular Weight

61,098 Da

OMIM

603048

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GPAA1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPAA1. It may not necessarily be applicable to this product.

NCBI GI #

13111996

NCBI GeneID

8733

NCBI Accession #

BC003171

UniProt Secondary Accession #

Q9NSS0; Q9UQ31

UniProt Related Accession #

O43292

NCBI Official Full Name

Homo sapiens glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast), mRNA

NCBI Official Synonym Full Names

glycosylphosphatidylinositol anchor attachment 1

NCBI Official Symbol

GPAA1

NCBI Official Synonym Symbols

GAA1; hGAA1

UniProt Protein Name

Glycosylphosphatidylinositol anchor attachment 1 protein

UniProt Synonym Protein Names

GAA1 protein homolog; hGAA1

Protein Family

Glycosylphosphatidylinositol anchor attachment 1 protein

UniProt Gene Name

GPAA1

UniProt Synonym Gene Names

GAA1; GPI anchor attachment protein 1; hGAA1

UniProt Entry Name

GPAA1_HUMAN

NCBI Protein Information

glycosylphosphatidylinositol anchor attachment 1 protein

NCBI Summary for GPAA1

Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]

UniProt Comments for GPAA1

GPAA1: Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membrane

Molecular Function: protein binding

Biological Process: attachment of GPI anchor to protein

Research Articles on GPAA1

1. the lumenal domain of GAA1/GPAA1 has a 3D structure similar to that of an M28-type aminopeptidase. GAA1/GPAA1 is a candidate for the enzyme that catalyzes the peptide bond formation between the omega-site and a phosphoethanolamine group of GPI lipid anchor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GPAA1 cdna clone

Products by Pathway	Pathway Diagram
Attachment Of GPI Anchor To UPAR Pathway antibodies	Attachment Of GPI Anchor To UPAR Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies	Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram

Diseases associated with GPAA1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with GPAA1 and Neoplasms
Nervous System Diseases Antibodies	>5 publications with GPAA1 and Nervous System Diseases
Breast Neoplasms Antibodies	>4 publications with GPAA1 and Breast Neoplasms
Carcinoma, Hepatocellular Antibodies	>2 publications with GPAA1 and Carcinoma, Hepatocellular
Heart Diseases Antibodies	>2 publications with GPAA1 and Heart Diseases
Liver Neoplasms Antibodies	>2 publications with GPAA1 and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with GPAA1 and Liver Diseases
Adenocarcinoma Antibodies	>2 publications with GPAA1 and Adenocarcinoma
Cell Transformation, Neoplastic Antibodies	>1 publications with GPAA1 and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>1 publications with GPAA1 and Lung Neoplasms

Organs/Tissues associated with GPAA1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with GPAA1 and Brain
Liver Antibodies	>2 publications with GPAA1 and Liver
Bladder Antibodies	>2 publications with GPAA1 and Bladder
Bone Antibodies	>1 publications with GPAA1 and Bone
Muscle Antibodies	>1 publications with GPAA1 and Muscle
Heart Antibodies	>1 publications with GPAA1 and Heart
Embryonic Tissue Antibodies	>1 publications with GPAA1 and Embryonic Tissue
Uterus Antibodies	>1 publications with GPAA1 and Uterus
Ovary Antibodies	>1 publications with GPAA1 and Ovary
Lung Antibodies	>1 publications with GPAA1 and Lung