Human GRP cDNA Clone Expression Plasmid – Cat# MBS1270591

GRP cDNA Clone – Gastrin-Releasing Peptide (Human)

Name: GRP cDNA Clone; Gastrin-Releasing Peptide; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270591
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270591

MBS1270591 is a cDNA clone targeting GRP. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GRP, cDNA Clone

Full Product Name

GRP cDNA Clone

Product Gene Name

GRP cdna clone

Sequence

atgcgcggcc gtgagctccc gctggtcctg ctggcgctgg tcctctgcct ggcgccccgg gggcgagcgg tcccgctgcc tgcgggcgga gggaccgtgc tgaccaagat gtacccgcgc ggcaaccact gggcggtggg gcacttaatg gggaaaaaga gcacagggga gtcttcttct gtttctgaga gagggagcct gaagcagcag ctgagagagt acatcaggtg ggaagaagct gcaaggaatt tgctgggtct catagaagca aaggagaaca gaaaccacca gccacctcaa cccaaggccc tgggcaatca gcagccttcg tgggattcag aggatagcag caacttcaaa gatgtaggtt caaaaggcaa agttggtaga ctctctgctc caggttctca acgtgaagga aggaaccccc agctgaacca gcaatga

Molecular Weight

15,533 Da

OMIM

137260

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GRP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GRP. It may not necessarily be applicable to this product.

NCBI GI #

33872823

NCBI GeneID

2922

NCBI Accession #

BC004488

UniProt Secondary Accession #

P07491; P81553; Q14454; Q53YA0; Q9BSY7

UniProt Related Accession #

P07492

NCBI Official Full Name

Homo sapiens gastrin-releasing peptide, mRNA

NCBI Official Synonym Full Names

gastrin releasing peptide

NCBI Official Symbol

GRP

NCBI Official Synonym Symbols

BN; GRP-10; proGRP; preproGRP

UniProt Protein Name

Gastrin-releasing peptide

UniProt Synonym Protein Names

Neuromedin-CAlternative name(s):GRP-10

Protein Family

Beta-1,3-glucan-binding protein

UniProt Gene Name

GRP

UniProt Synonym Gene Names

GRP

UniProt Entry Name

GRP_HUMAN

NCBI Protein Information

gastrin-releasing peptide

NCBI Summary for GRP

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

UniProt Comments for GRP

GRP: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear. Belongs to the bombesin/neuromedin-B/ranatensin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18q21.1-q21.32

Cellular Component: extracellular region; extracellular space

Molecular Function: neuropeptide hormone activity

Biological Process: neuropeptide signaling pathway

Research Articles on GRP

1. Data show that serum neuron-specific enolase, cytokeratin 19 fragment 21-1, pro-gastrin-releasing peptide, squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GRP cdna clone

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Incretin Synthesis, Secretion, And Inactivation Pathway antibodies	Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with GRP cdna clone

Disease Name	Pubmed Publications
Carcinoma Antibodies	>392 publications with GRP and Carcinoma
Adenocarcinoma Antibodies	>129 publications with GRP and Adenocarcinoma
Carcinoma, Non-Small-Cell Lung Antibodies	>99 publications with GRP and Carcinoma, Non-Small-Cell Lung
Inflammation Antibodies	>91 publications with GRP and Inflammation
Drug Toxicity Antibodies	>53 publications with GRP and Drug Toxicity
Liver Diseases Antibodies	>52 publications with GRP and Liver Diseases
Necrosis Antibodies	>47 publications with GRP and Necrosis
Liver Neoplasms Antibodies	>37 publications with GRP and Liver Neoplasms
Fibrosis Antibodies	>37 publications with GRP and Fibrosis
Head and Neck Neoplasms Antibodies	>35 publications with GRP and Head and Neck Neoplasms

Organs/Tissues associated with GRP cdna clone

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>388 publications with GRP and Lung
Brain Antibodies	>373 publications with GRP and Brain
Pancreas Antibodies	>213 publications with GRP and Pancreas
Prostate Antibodies	>171 publications with GRP and Prostate
Uterus Antibodies	>38 publications with GRP and Uterus
Eye Antibodies	>32 publications with GRP and Eye
Testis Antibodies	>9 publications with GRP and Testis
Parathyroid Antibodies	>5 publications with GRP and Parathyroid
Pineal Gland Antibodies	>1 publications with GRP and Pineal Gland