Human GTF2F1 cDNA Clone Expression Plasmid – Cat# MBS1276509

GTF2F1 cDNA Clone – General Transcription Factor IIF, Polypeptide 1, 74kDa (Human)

Name: GTF2F1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276509
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276509

MBS1276509 is a cDNA clone targeting GTF2F1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GTF2F1, cDNA Clone

Full Product Name

GTF2F1 cDNA Clone

Product Gene Name

GTF2F1 cdna clone

Sequence

atggcggccc taggccctag cagccagaat gtcactgaat acgtcgttcg agttcctaag aatacaacca aaaaatataa catcatggct tttaatgcag ccgacaaagt caactttgct acgtggaatc aggctcggct ggagcgggac ttgagcaaca agaaaatcta ccaagaggag gagatgcccg aatcgggcgc gggcagtgag ttcaaccgca agcttcggga ggaggctcgg aggaagaagt acggcatcgt cctcaaggag ttccggcccg aggaccagcc ctggctgctc cgggtcaacg gcaaatcagg caggaagttc aagggcatca agaagggagg cgtaacagag aacacgtcct actacatctt cacccagtgc cccgacgggg ccttcgaggc cttccccgtg cacaactggt acaatttcac accgctggcc cggcatcgca cgctcactgc cgaggaggcc gaggaggagt gggagaggag gaacaaggtg ctgaaccact tcagcatcat gcagcagcgg cggctcaagg atcaggacca ggacgaggat gaggaggaga aggagaaacg tggccgcagg aaggcgagcg agctgcgcat ccacgacctg gaggacgacc tggagatgtc gtccgatgcc agtgatgcca gtggtgagga ggggggcaga gtccccaagg ccaagaagaa ggcgccgctg gccaagggcg gcaggaaaaa gaagaagaag aagggttcag acgacgaggc cttcgaggac agcgatgatg gggacttcga gggccaagag gtggactaca tgtcagacgg ctccagtagc tcccaagaag agcctgagag caaggccaag gcgccgcagc aggaggaggg gcccaagggt gtcgatgagc agagcgacag tagtgaggag agtgaggagg agaagccgcc tgaggaggac aaggaggagg aggaggagaa gaaggcaccc accccgcagg agaagaagcg caggaaagac agcagcgagg agtcggacag ctcagaggag agcgacattg acagcgaggc ctcctcagcc ctcttcatgg cgaagaagaa gacgccaccc aagagagagc ggaagccgtc gggagggagc tcaaggggca acagccgccc aggcacgccc agcgcagagg gtggcagcac ctcctccacc ctgcgggcgg ctgccagcaa actcgagcaa gggaagcggg tgagcgagat gcctgcagcc aagcggttgc ggctggacac gggaccccag agcctgtctg ggaagtcgac accccagcca ccatcaggca agacaacacc caacagcggc gacgtgcagg tgactgagga tgccgtgcgc cgctacctga cacggaagcc catgaccact aaggacctgc tgaaaaagtt ccagaccaag aagacagggc tgagcagcga gcagacagtg aacgtgttgg cccagatcct caagcgactc aaccccgagc gcaagatgat caacgacaaa atgcacttct ccctcaagga gtga

Molecular Weight

58,240 Da

OMIM

189968

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GTF2F1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2F1. It may not necessarily be applicable to this product.

NCBI GI #

12652738

NCBI GeneID

2962

NCBI Accession #

BC000120

UniProt Secondary Accession #

Q9BWN0; B2RCS0

UniProt Related Accession #

P35269

NCBI Official Full Name

Homo sapiens general transcription factor IIF, polypeptide 1, 74kDa, mRNA

NCBI Official Synonym Full Names

general transcription factor IIF subunit 1

NCBI Official Symbol

GTF2F1

NCBI Official Synonym Symbols

BTF4; RAP74; TF2F1; TFIIF

UniProt Protein Name

General transcription factor IIF subunit 1

UniProt Synonym Protein Names

General transcription factor IIF 74 kDa subunit; Transcription initiation factor IIF subunit alpha; TFIIF-alpha; Transcription initiation factor RAP74

Protein Family

General transcription factor

UniProt Gene Name

GTF2F1

UniProt Synonym Gene Names

RAP74; TFIIF-alpha

UniProt Entry Name

T2FA_HUMAN

NCBI Protein Information

general transcription factor IIF subunit 1

UniProt Comments for GTF2F1

GTF2F1: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2, CTDP1, TAF6/TAFII80 and URI1. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the TFIIF alpha subunit family.

Protein type: Kinase, protein; EC 2.7.11.1; Transcription initiation complex; ATYPICAL group; GTF2F1 family

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell junction; intracellular membrane-bound organelle; nucleoplasm; nucleus; transcription factor TFIIF complex

Molecular Function: phosphatase activator activity; protein binding; transcription coactivator activity; transcription factor binding

Biological Process: fibroblast growth factor receptor signaling pathway; gene expression; mRNA capping; nuclear mRNA splicing, via spliceosome; positive regulation of viral transcription; response to virus; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter

Research Articles on GTF2F1

1. These results suggest that Mediator structural shifts induced by activator binding help stably orient pol II prior to transcription initiation within the human mediator-RNA polymerase II-TFIIF assembly.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GTF2F1 cdna clone

Products by Pathway	Pathway Diagram
Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies	Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway Diagram
Formation Of RNA Pol II Elongation Complex Pathway antibodies	Formation Of RNA Pol II Elongation Complex Pathway Diagram
Formation Of The Early Elongation Complex Pathway antibodies	Formation Of The Early Elongation Complex Pathway Diagram
Formation Of The HIV-1 Early Elongation Complex Pathway antibodies	Formation Of The HIV-1 Early Elongation Complex Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram