Human GTF2IRD2 cDNA Clone Expression Plasmid – Cat# MBS1267566

GTF2IRD2 cDNA Clone – GTF2I Repeat Domain Containing 2 (Human)

Name: GTF2IRD2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267566
Price: 345 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267566

MBS1267566 is a cDNA clone targeting GTF2IRD2. More details

$345 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GTF2IRD2, cDNA Clone

Full Product Name

GTF2IRD2 cDNA Clone

Product Gene Name

GTF2IRD2 cdna clone

Sequence

atggcccagg tagcagtgtc caccctgcct gttgaagaag agtcctcctc agagaccagg atggtggtga cattcctcgt gtctgccctc gaatccatgt gtaaagaact ggccgagtcc aaggcagaag tggcctgcat cgcagtgtac gaaacagacg tgtttgtcgt cggaaccgag agaggatgcg cttttgttaa tgccaggacg gattttcaga aagattttgc aaaatactgc gttgcagagg gactgtgtga ggtgaaacct ccctgccctg tgaacgggat gcaggtccac tcgggcgaaa cggaaatact caggaaggca gtggaggact atttctgctt ttgttatggt aaagccttag ggacaacagt gatggtgcct gttccctatg agaagatgct gcgagaccag tcggctgtgg tagtgcaggg gcttccggaa ggcgttgcct ttcaacaccc tgagaattac gaccttgcaa ccctgaaatg gattttggag aacaaagcag ggatttcatt catcataaat agacccttcc taggaccaga gagtcagctg ggtggccctg ggatggtaac agatgcggag agatccatag tatcaccaag tgaaagctgc ggccccatca atgtgaaaac tgaacccatg gaagattctg gtgggtacca agatgctttt agaatcaagt atcggccaag cgtggtagct cacgcctgta atcccagcaa tttgggaggc cgaggcaggc ggatcacttg a

Molecular Weight

57,245 Da

OMIM

608899

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GTF2IRD2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2IRD2. It may not necessarily be applicable to this product.

NCBI GI #

28839282

NCBI GeneID

84163

NCBI Accession #

BC047706

UniProt Secondary Accession #

Q69G40; Q6EKI8; Q6EKI9; Q6NVW2; Q6P7N8; Q86WX4; Q8ND85; Q8NDE5; A8K5W6; B3KUZ2

UniProt Related Accession #

Q86UP8

NCBI Official Full Name

Homo sapiens GTF2I repeat domain containing 2, mRNA

NCBI Official Synonym Full Names

GTF2I repeat domain containing 2

NCBI Official Symbol

GTF2IRD2

NCBI Official Synonym Symbols

FP630; GTF2IRD2A; GTF2IRD2 alpha

UniProt Protein Name

General transcription factor II-I repeat domain-containing protein 2A

UniProt Synonym Protein Names

Transcription factor GTF2IRD2-alpha

Protein Family

General transcription factor II-I repeat domain-containing protein

UniProt Gene Name

GTF2IRD2

UniProt Synonym Gene Names

GTF2IRD2A; GTF2I repeat domain-containing protein 2A

UniProt Entry Name

GTD2A_HUMAN

NCBI Protein Information

general transcription factor II-I repeat domain-containing protein 2A

NCBI Summary for GTF2IRD2

This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniProt Comments for GTF2IRD2

GTF2IRD2: GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the TFII-I family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7q11.23

Research Articles on GTF2IRD2

1. We provide the first evidence for a role for GTF2IRD2 in higher-level (executive functioning) abilities and highlight the importance of integrating detailed molecular characterisation of patients with comprehensive neuropsychological profiling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with GTF2IRD2 cdna clone

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>10 publications with GTF2IRD2 and Congenital Abnormalities
Vascular Diseases Antibodies	>1 publications with GTF2IRD2 and Vascular Diseases

Organs/Tissues associated with GTF2IRD2 cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>8 publications with GTF2IRD2 and Muscle
Brain Antibodies	>3 publications with GTF2IRD2 and Brain
Mouth Antibodies	>1 publications with GTF2IRD2 and Mouth
Connective Tissue Antibodies	>1 publications with GTF2IRD2 and Connective Tissue