Human HAT1 cDNA Clone Expression Plasmid – Cat# MBS1270760

HAT1 cDNA Clone – Histone Acetyltransferase 1 (Human)

Name: HAT1 cDNA Clone; Histone Acetyltransferase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270760
Price: 500 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270760

MBS1270760 is a cDNA clone targeting HAT1. More details

$500 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HAT1, cDNA Clone

Full Product Name

HAT1 cDNA Clone

Product Gene Name

HAT1 cdna clone

Sequence

ATGGAGAAAT TTTTGGTAGA ATATAAGAGT GCAGTGGAGA AGAAACTGGC AGAGTACAAA TGTAACACCA ACACAGCAAT TGAACTAAAA TTAGTTCGTT TTCCTGAAGA TCTTGAAAAT GACATTAGAA CTTTCTTTCC TGAGTATACC CATCAACTCT TTGGGGATGA TGAAACTGCT TTTGGTTACA AGGGTCTAAA GATCCTGTTA TACTATATTG CTGGTAGCCT GTCAACAATG TTCCGTGTTG AATATGCATC TAAAGTTGAT GAGAACTTTG ACTGTGTAGA GGCAGATGAT GTTGAGGGCA AAATTAGACA AATCATTCCA CCTGGATTTT GCACAAACAC GAATGATTTC CTTTCTTTAC TGGAAAAGGA AGTTGATTTC AAGCCATTCG GAACCTTACT TCATACCTAC TCAGTTCTCA GTCCAACAGG AGGAGAAAAC TTTACCTTTC AGATATATAA GGCTGACATG ACATGTAGAG GCTTTCGAGA ATATCATGAA AGGCTTCAGA CCTTTTTGAT GTGGTTTATT GAAACTGCTA GCTTTATTGA CGTGGATGAT GAAAGATGGC ACTACTTTCT AGTATTTGAG AAGTATAATA AGGATGGAGC TACGCTCTTT GCGACCGTAG GCTACATGAC AGTCTATAAT TACTATGTGT ACCCAGACAA AACCCGGCCA CGTGTAAGTC AGATGCTGAT TTTGACTCCA TTTCAAGGTC AAGGCCATGG TGCTCAACTT CTTGAAACAG TTCATAGATA CTACACTGAA TTTCCTACAG TTCTTGATAT TACAGCGGAA GATCCATCCA AAAGCTATGT GAAATTACGA GACTTTGTGC TTGTGAAGCT TTGTCAAGAT TTGCCCTGTT TTTCCCGGGA AAAATTAATG CAAGGATTCA ATGAAGATAT GGCGATAGAG GCACAACAGA AGTTCAAAAT AAATAAGCAA CACGCTAGAA GGGTTTATGA AATTCTTCGA CTACTGGTAA CTGACATGAG TGATGCCGAA CAATACAGAA GCTACAGACT GGATATTAAA AGAAGACTAA TTAGCCCATA TAAGAAAAAG CAGAGAGATC TTGCTAAGAT GAGAAAATGT CTCAGACCAG AAGAACTGAC AAACCAGATG AACCAAATAG AAATAAGCAT GCAACATGAA CAGCTGGAAG AGAGTTTTCA GGAACTAGTG GAAGATTACC GGCGTGTTAT TGAACGACTT GCTCAAGAGT AA

Molecular Weight

39,786 Da

OMIM

603053

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HAT1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HAT1. It may not necessarily be applicable to this product.

NCBI GI #

71297072

NCBI GeneID

8520

NCBI Accession #

BC045673

UniProt Secondary Accession #

Q49A44; Q53QF0; Q53SU4; Q6P594; Q8WWB9

UniProt Related Accession #

O14929

NCBI Official Full Name

Homo sapiens histone acetyltransferase 1, mRNA

NCBI Official Synonym Full Names

histone acetyltransferase 1

NCBI Official Symbol

HAT1

NCBI Official Synonym Symbols

KAT1

UniProt Protein Name

Histone acetyltransferase type B catalytic subunit

UniProt Synonym Protein Names

Histone acetyltransferase 1

Protein Family

Histone acetyltransferase

UniProt Gene Name

HAT1

UniProt Synonym Gene Names

KAT1

UniProt Entry Name

HAT1_HUMAN

NCBI Protein Information

histone acetyltransferase type B catalytic subunit

NCBI Summary for HAT1

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]

UniProt Comments for HAT1

HAT1: Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. Belongs to the HAT1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.48; Acetyltransferase

Chromosomal Location of Human Ortholog: 2q31.2-q33.1

Cellular Component: intracellular membrane-bound organelle; nuclear chromatin; nuclear chromosome, telomeric region; nucleoplasm; nucleus; protein complex

Molecular Function: H4 histone acetyltransferase activity; histone acetyltransferase activity; histone binding; protein binding

Biological Process: DNA packaging; DNA replication-dependent nucleosome assembly; DNA replication-independent nucleosome assembly; internal protein amino acid acetylation

Research Articles on HAT1

1. These data indicated that miR-486 aggravate the cholesterol accumulation in THP-1 cells by targeting HAT1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HAT1 cdna clone

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram

Diseases associated with HAT1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with HAT1 and Neoplasms
Proteinuria Antibodies	>2 publications with HAT1 and Proteinuria
Neoplasms, Experimental Antibodies	>1 publications with HAT1 and Neoplasms, Experimental
Prostatic Diseases Antibodies	>1 publications with HAT1 and Prostatic Diseases
Carcinoma Antibodies	>1 publications with HAT1 and Carcinoma
Lung Neoplasms Antibodies	>1 publications with HAT1 and Lung Neoplasms
Hypertrophy Antibodies	>1 publications with HAT1 and Hypertrophy
Kidney Diseases Antibodies	>1 publications with HAT1 and Kidney Diseases
Prostatic Neoplasms Antibodies	>1 publications with HAT1 and Prostatic Neoplasms
Adenocarcinoma Antibodies	>1 publications with HAT1 and Adenocarcinoma

Organs/Tissues associated with HAT1 cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>4 publications with HAT1 and Muscle
Heart Antibodies	>4 publications with HAT1 and Heart
Lung Antibodies	>3 publications with HAT1 and Lung
Brain Antibodies	>3 publications with HAT1 and Brain
Kidney Antibodies	>3 publications with HAT1 and Kidney
Vascular Antibodies	>2 publications with HAT1 and Vascular
Blood Antibodies	>2 publications with HAT1 and Blood
Liver Antibodies	>2 publications with HAT1 and Liver
Ovary Antibodies	>1 publications with HAT1 and Ovary
Intestine Antibodies	>1 publications with HAT1 and Intestine