Human HDAC10 cDNA Clone Expression Plasmid – Cat# MBS1278069

HDAC10 cDNA Clone – Histone Deacetylase 10 (Human)

Name: HDAC10 cDNA Clone; Histone Deacetylase 10; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278069
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278069

MBS1278069 is a cDNA clone targeting HDAC10. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HDAC10, cDNA Clone

Full Product Name

HDAC10 cDNA Clone

Product Gene Name

HDAC10 cdna clone

Sequence

ATGGGGACCG CGCTTGTGTA CCATGAGGAC ATGACGGCCA CCCGGCTGCT CTGGGACGAC CCCGAGTGCG AGATCGAGCG TCCTGAGCGC CTGACCGCAG CCCTGGATCG CCTGCGGCAG CGCGGCCTGG AACAGAGGTG TCTGCGGTTG TCAGCCCGCG AGGCCTCGGA AGAGGAGCTG GGCCTGGTGC ACAGCCCAGA GTATGTATCC CTGGTCAGGG AGACCCAGGT CCTAGGCAAG GAGGAGCTGC AGGCGCTGTC CGGACAGTTC GACGCCATCT ACTTCCACCC GAGTACCTTT CACTGCGCGC GGCTGGCCGC AGGGGCTGGA CTGCAGCTGG TGGACGCTGT GCTCACTGGA GCTGTGCAAA ATGGGCTTGC CCTGGTGAGG CCTCCCGGGC ACCATGGCCA GAGGGCGGCT GCCAACGGGT TCTGTGTGTT CAACAACGTG GCCATAGCAG CTGCACATGC CAAGCAGAAA CACGGGCTAC ACAGGATCCT CGTCGTGGAC TGGGATGTGC ACCATGGCCA GGGGATCCAG TATCTCTTTG AGGATGACCC CAGCGTCCTT TACTTCTCCT GGCACCGCTA TGAGCATGGG CGCTTCTGGC CTTTCCTGCG AGAGTCAGAT GCAGACGCAG TGGGGCGGGG ACAGGGCCTC GGCTTCACTG TCAACCTGCC CTGGAACCAG GTTGGGATGG GAAACGCTGA CTACGTGGCT GCCTTCCTGC ACCTGCTGCT CCCACTGGCC TTTGAGTTTG ACCCTGAGCT GGTGCTGGTC TCGGCAGGAT TTGACTCAGC CATCGGGGAC CCTGAGGGGC AAATGCAGGC CACGCCAGAG TGCTTCGCCC ACCTCACACA GCTGCTGCAG GTGCTGGCCG GCGGCCGGGT CTGTGCCGTG CTGGAGGGCG GCTACCACCT GGAGTCACTG GCGGAGTCAG TGTGCATGAC AGTACAGACG CTGCTGGGTG ACCCGGCCCC ACCCCTGTCA GGGCCAATGG CGCCATGTCA GAGTGCCCTA GAGTCCATCC AGAGTGCCCG TGCTGCCCAG GCCCCGCACT GGAAGAGCCT CCAGCAGCAA GATGTGACCG CTGTGCCGAT GAGCCCCAGC AGCCACTCCC CAGAGGGGAG GCCTCCACCT CTGCTGCCTG GGGGTCCAGT GTGTAAGGCA GCTGCATCTG CACCGAGCTC CCTCCTGGAC CAGCCGTGCC TCTGCCCCGC ACCCTCTGTC CGCACCGCTG TTGCCCTGAC AACGCCGGAT ATCACATTGG TTCTGCCCCC TGACGTCATC CAACAGGAAG CGTCAGCCCT GAGGGAGGAG ACAGAAGCCT GGGCCAGGCC ACACGAGTCC CTGGCCCGGG AGGAGGCCCT CACTGCACTT GGGAAGCTCC TGTACCTCTT AGATGGGATG CTGGATGGGC AGGTGAACAG TGGTATAGCA GCCACTCCAG CCTCTGCTGC AGCAGCCACC CTGGATGTGG CTGTTCGGAG AGGCCTGTCC CACGGAGCCC AGAGGCTGCT GTGCGTGGCC CTGGGACAGC TGGACCGGCC TCCAGACCTC GCCCATGACG GGAGGAGTCT GTGGCTGAAC ATCAGGGGCA AGGAGGCGGC TGCCCTATCC ATGTTCCATG TCTCCACGCC ACTGCCAGTG ATGACCGGTG GTTTCCTGAG CTGCATCTTG GGCTTGGTGC TGCCCCTGGC CTATGGCTTC CAGCCTGACC TGGTGCTGGT GGCGCTGGGG CCTGGCCATG GCCTGCAGGG CCCCCACGCT GCACTCCTGG CTGCAATGCT TCGGGGGCTG GCAGGGGGCC GAGTCCTGGC CCTCCTGGAG GAGAACTCCA CACCCCAGCT AGCAGGGATC CTGGCCCGGG TGCTGAATGG AGAGGCACCT CCTAGCCTAG GCCCTTCCTC TGTGGCCTCC CCAGAGGACG TCCAGGCCCT GATGTACCTG AGAGGGCAGC TGGAGCCTCA GTGGAAGATG TTGCAGTGCC ATCCTCACCT GGTGGCTTGA

Molecular Weight

43,016 Da

OMIM

608544

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HDAC10 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HDAC10. It may not necessarily be applicable to this product.

NCBI GI #

115527736

NCBI GeneID

83933

NCBI Accession #

BC125083

UniProt Secondary Accession #

Q08AP4; Q6STF9; Q96P77; Q96P78; Q9H028; Q9UGX1; Q9UGX2

UniProt Related Accession #

Q969S8

NCBI Official Full Name

Homo sapiens histone deacetylase 10, mRNA

NCBI Official Synonym Full Names

histone deacetylase 10

NCBI Official Symbol

HDAC10

NCBI Official Synonym Symbols

HD10

UniProt Protein Name

Histone deacetylase 10

Protein Family

Histone deacetylase

UniProt Gene Name

HDAC10

UniProt Synonym Gene Names

HD10

UniProt Entry Name

HDA10_HUMAN

NCBI Protein Information

histone deacetylase 10

NCBI Summary for HDAC10

The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for HDAC10

HDAC10: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Belongs to the histone deacetylase family. HD type 2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Deacetylase; EC 3.5.1.98

Chromosomal Location of Human Ortholog: 22q13.31

Cellular Component: cytoplasm; histone deacetylase complex; nucleoplasm; nucleus

Molecular Function: enzyme binding; histone deacetylase activity; histone deacetylase binding; protein binding; protein deacetylase activity

Biological Process: histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; protein amino acid deacetylation; regulation of transcription, DNA-dependent

Research Articles on HDAC10

1. HDAC10 regulates cyclin A2 expression by deacetylating histones near the let-7 promoter.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HDAC10 cdna clone

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
FBXW7 Mutants And NOTCH1 In Cancer Pathway antibodies	FBXW7 Mutants And NOTCH1 In Cancer Pathway Diagram
NOTCH1 Intracellular Domain Regulates Transcription Pathway antibodies	NOTCH1 Intracellular Domain Regulates Transcription Pathway Diagram
Neural Crest Differentiation Pathway antibodies	Neural Crest Differentiation Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By NOTCH Pathway antibodies	Signaling By NOTCH Pathway Diagram

Diseases associated with HDAC10 cdna clone

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>3 publications with HDAC10 and Lung Neoplasms
Liver Diseases Antibodies	>1 publications with HDAC10 and Liver Diseases
Hepatitis Antibodies	>1 publications with HDAC10 and Hepatitis
Adenoma Antibodies	>1 publications with HDAC10 and Adenoma
Carcinoma, Hepatocellular Antibodies	>1 publications with HDAC10 and Carcinoma, Hepatocellular
Seizures Antibodies	>1 publications with HDAC10 and Seizures
Liver Neoplasms Antibodies	>1 publications with HDAC10 and Liver Neoplasms

Organs/Tissues associated with HDAC10 cdna clone

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with HDAC10 and Lung
Blood Antibodies	>4 publications with HDAC10 and Blood
Stomach Antibodies	>2 publications with HDAC10 and Stomach
Brain Antibodies	>2 publications with HDAC10 and Brain
Bone Antibodies	>1 publications with HDAC10 and Bone
Adrenal Gland Antibodies	>1 publications with HDAC10 and Adrenal Gland
Embryonic Tissue Antibodies	>1 publications with HDAC10 and Embryonic Tissue
Vascular Antibodies	>1 publications with HDAC10 and Vascular
Liver Antibodies	>1 publications with HDAC10 and Liver