Human HK3 cDNA Clone Expression Plasmid – Cat# MBS1266848

HK3 cDNA Clone – Hexokinase 3 (White Cell) (Human)

Name: HK3 cDNA Clone; Hexokinase 3 (White Cell); Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266848
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266848

MBS1266848 is a cDNA clone targeting HK3. More details

$630 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HK3, cDNA Clone

Full Product Name

HK3 cDNA Clone

Product Gene Name

HK3 cdna clone

Sequence

atggactcca ttgggtcttc agggttgcgg cagggggaag aaaccctgag ttgctctgag gagggcttgc ccgggccctc agacagctca gagctggtgc aggagtgcct gcagcagttc aaggtgacaa gggcacagct acagcagatc caagccagcc tcttgggttc catggagcag gcgctgaggg gacaggccag ccctgcccct gcggtccgga tgctgcctac atacgtgggg tccaccccac atggcactga gcaaggagac ttcgtggtgc tggagctggg ggccacaggg gcctcactgc gtgttttgtg ggtgactcta actggcattg aggggcatag ggtggagccc agaagccagg agtttgtgat cccccaagag gtgatgctgg gtgctggcca gcagctcttt gactttgctg cccactgcct gtctgagttc ctggatgcgc agcctgtgaa caaacagggt ctgcagcttg gcttcagctt ctctttccct tgtcaccaga cgggcttgga caggagcacc ctcatttcct ggaccaaagg ttttaggtgc agtggtgtgg aaggccagga tgtggtccag ctgctgagag atgccattcg gaggcagggg gcctacaaca tcgacgtggt tgctgtggtg aacgacacag tgggcaccat gatgggctgt gagccggggg tcaggccgtg tgaggttggg ctagttgtag acacgggcac caacgcgtgt tacatggagg aggcacggca tgtggcagtg ctggacgaag accggggccg cgtctgcgtc agcgtcgagt ggggctcctt cagcgatgat ggggcgctgg gaccagtgct gaccaccttc gaccataccc tggaccatga gtccctgaat cctggtgctc agaggtttga gaagatgatc ggaggcctgt acctgggtga gctggtgcgg ctggtgctgg ctcacttggc ccggtgtggg gtcctctttg gtggctgcac ctcccctgcc ctgctgagcc aaggcagcat cctcctggaa cacgtggctg agatggagga cccctctact ggggcagccc gtgtccatgc tatcctgcag gacttgggcc tgagccctgg ggcttcggat gttgagcttg tgcagcacgt ctgtgcggcc gtgtgcacgc gggctgccca gctctgtgct gccgccctgg ccgctgttct ctcctgcctc cagcacagcc gggagcaaca aacactccag gttgctgtgg ccaccggagg ccgagtgtgt gagcggcacc ccaggttctg cagcgtcctg caggggacag tgatgctcct ggccccggaa tgcgatgtct ccttaatccc ctctgtggat ggtggtggcc ggggagtggc gatggtgact gctgtggctg cccgtctggc tgcccaccgg cgcctgctgg aggagaccct ggccccattc cggttgaacc atgatcaact ggctgcggtt caggcacaga tgcggaaggc catggccaag gggctccgag gggaggcctc ctcccttcgc atgctgccca ctttcgtccg ggccacccct gatggcagcg agcgagggga tttcctggcc ctggacctcg ggggcacgaa cttccgtgtc ctcctggtac gtgtgaccac aggcgtgcag atcaccagcg agatctactc cattcccgag actgtggccc agggttctgg gcagcagctc tttgaccaca tcgtggactg catcgtggac ttccagcaga agcagggcct gagcgggcag agcctcccac tgggttttac cttctccttc ccatgtaggc agcttggcct agaccagggc atcctcctga actggaccaa gggtttcaag gcatcagact gcgagggcca agatgtcgtg agtctgttgc gggaagccat cactcgcaga caggcagtgg agctgaatgt ggttgccatt gtcaatgaca cggtggggac catgatgtcc tgtggctatg aggacccccg ttgcgagata ggcctcattg tcggaaccgg caccaatgcc tgctacatgg aggagctccg gaatgtggcg ggcgtgcctg gggactcagg ccgcatgtgc atcaacatgg agtggggcgc ctttggggac gatggctctc tggccatgct cagcacccgc tttgatgcaa gtgtggacca ggcgtccatc aaccccggca agcagaggtt tgaaaagatg atcagcggca tgtacctggg ggagatcgtc cgccacatcc ttttacattt aaccagcctt ggcgttctct tccggggcca gcagatccag cgccttcaga ccagggacat cttcaagacc aagttcctct ctgagatcga aagtgacagc ctggccctgc ggcaggtccg agccatccta gaggatctgg ggctacccct gacctcagat gacgccctga tggtgctaga ggtgtgccag gctgtgtccc agagggctgc ccagctctgt ggggcgggtg tagctgccgt ggtggagaag atccgggaga accggggcct ggaagagctg gcagtgtctg tgggggtgga tggaacgctc tacaagctgc acccgcgctt ctccagcctg gtggcggcca cagtgcggga gctggcccct cgctgtgtgg tcacgttcct gcagtcagag gatgggtccg gcaaaggtgc ggccctggtc accgctgttg cctgccgcct tgcgcagttg actcgtgtct ga

Molecular Weight

99,025 Da

OMIM

142570

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HK3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HK3. It may not necessarily be applicable to this product.

NCBI GI #

20380887

NCBI GeneID

3101

NCBI Accession #

BC028129

UniProt Secondary Accession #

Q8N1E7

UniProt Related Accession #

P52790

NCBI Official Full Name

Homo sapiens hexokinase 3 (white cell), mRNA

NCBI Official Synonym Full Names

hexokinase 3

NCBI Official Symbol

HK3

NCBI Official Synonym Symbols

HXK3; HKIII

UniProt Protein Name

Hexokinase-3

UniProt Synonym Protein Names

Hexokinase type III; HK III

Protein Family

Probable histidine kinase

UniProt Gene Name

HK3

UniProt Synonym Gene Names

HK III

UniProt Entry Name

HXK3_HUMAN

NCBI Protein Information

hexokinase-3

NCBI Summary for HK3

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]

UniProt Comments for HK3

HK3: a glycolytic enzyme that catalyzes the reaction ATP + D-hexose = ADP + D-hexose 6-phosphate. The first and rate-limiting step in glycosis, a pathway that produces energy in the form of ATP from glucose. An allosteric enzyme inhibited by its product glucose-6-phosphate (Glc-6-P). Acts as a ""glucose sensor"" by trapping glucose inside the cell by catalyzing its phosphorylation to produce Glc-6-P. In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).

Protein type: Enzyme, cellular metabolism; Kinase, other; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 2.7.1.1; Transferase; Carbohydrate Metabolism - galactose

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: cytosol

Molecular Function: fructokinase activity; glucokinase activity; hexokinase activity; mannokinase activity

Biological Process: cell glucose homeostasis; glucose transport; glycolysis

Research Articles on HK3

1. The transport of glucose across the cell membrane by glucose transporters (GLUTs) and intracellular phosphorylation by hexokinases (HKs) are the initial steps of the glycolytic pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HK3 cdna clone

Products by Pathway	Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
Butirosin And Neomycin Biosynthesis Pathway antibodies	Butirosin And Neomycin Biosynthesis Pathway Diagram
Butirosin And Neomycin Biosynthesis Pathway antibodies	Butirosin And Neomycin Biosynthesis Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram

Diseases associated with HK3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>36 publications with HK3 and Neoplasms
Carcinoma Antibodies	>10 publications with HK3 and Carcinoma
Hyperplasia Antibodies	>7 publications with HK3 and Hyperplasia
Neoplasm Metastasis Antibodies	>4 publications with HK3 and Neoplasm Metastasis
Hepatitis Antibodies	>2 publications with HK3 and Hepatitis
Liver Neoplasms Antibodies	>2 publications with HK3 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>2 publications with HK3 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>2 publications with HK3 and Liver Diseases
Lung Neoplasms Antibodies	>1 publications with HK3 and Lung Neoplasms
Fibrosis Antibodies	>1 publications with HK3 and Fibrosis

Organs/Tissues associated with HK3 cdna clone

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>53 publications with HK3 and Prostate
Blood Antibodies	>18 publications with HK3 and Blood
Brain Antibodies	>5 publications with HK3 and Brain
Skin Antibodies	>5 publications with HK3 and Skin
Testis Antibodies	>5 publications with HK3 and Testis
Muscle Antibodies	>2 publications with HK3 and Muscle
Lung Antibodies	>2 publications with HK3 and Lung
Connective Tissue Antibodies	>1 publications with HK3 and Connective Tissue