Human HNRPDL cDNA Clone Expression Plasmid – Cat# MBS1268911

HNRPDL cDNA Clone – Heterogeneous Nuclear Ribonucleoprotein D-Like (Human)

Name: HNRPDL cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268911
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268911

MBS1268911 is a cDNA clone targeting HNRPDL. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HNRPDL, cDNA Clone

Full Product Name

HNRPDL cDNA Clone

Product Gene Name

HNRPDL cdna clone

Sequence

atggaggata tgaacgagta cagcaatata gaggaattcg cagagggatc caagatcaac gcgagcaaga atcagcagga tgacggtaaa atgtttattg gaggcttgag ctgggataca agcaaaaaag atctgacaga gtacttgtct cgatttgggg aagttgtaga ctgcacaatt aaaacagatc cagtcactgg gagatcaaga ggatttggat ttgtgctttt caaagatgct gctagtgttg ataaggtttt ggaactgaaa gaacacaaac tggatggcaa attgatagat cccaaaaggg ccaaagcttt aaaagggaaa gaacctccca aaaaggtttt tgtgggtgga ttgagcccgg atacttctga agaacaaatt aaagaatatt ttggagcctt tggagagatt gaaaatattg aacttcccat ggatacaaaa acaaatgaaa gaagaggatt ttgttttatc acatatactg atgaagagcc agtaaaaaaa ttgttagaaa gcagatacca tcaaattggt tctgggaagt gtgaaatcaa agttgcacaa cccaaagagg tatataggca gcaacagcaa caacaaaaag gtggaagagg tgctgcagct ggtggacgag gtggtacgag gggtcgtggc cgaggtcagg gccaaaactg gaaccaagga tttaataact attatgatca aggatatgga aattacaata gtgcctatgg tggtgatcaa aactatagtg gctatggcgg atatgattat actgggtata actatgggaa ctatggatat ggacagggat atgcagacta cagtggccaa cagagcactt atggcaaggc atctcgaggg ggtggcaatc accaaaacaa ttaccagcca tactaa

Molecular Weight

27,191 Da

OMIM

607137

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HNRPDL cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HNRPDL. It may not necessarily be applicable to this product.

NCBI GI #

39644770

NCBI GeneID

9987

NCBI Accession #

BC007392

UniProt Secondary Accession #

Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43

UniProt Related Accession #

O14979

NCBI Official Full Name

Homo sapiens heterogeneous nuclear ribonucleoprotein D-like, mRNA

NCBI Official Synonym Full Names

heterogeneous nuclear ribonucleoprotein D like

NCBI Official Symbol

HNRNPDL

NCBI Official Synonym Symbols

HNRNP; JKTBP; HNRPDL; JKTBP2; LGMD1G; laAUF1

UniProt Protein Name

Heterogeneous nuclear ribonucleoprotein D-like

UniProt Synonym Protein Names

AU-rich element RNA-binding factor; JKT41-binding protein; Protein laAUF1

UniProt Gene Name

HNRNPDL

UniProt Synonym Gene Names

HNRPDL; JKTBP; hnRNP D-like; hnRNP DL

UniProt Entry Name

HNRDL_HUMAN

NCBI Protein Information

heterogeneous nuclear ribonucleoprotein D-like

NCBI Summary for HNRPDL

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]

UniProt Comments for HNRPDL

hnRNP D-like: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; DNA-binding; RNA processing

Chromosomal Location of Human Ortholog: 4q21.22

Cellular Component: nucleoplasm

Molecular Function: protein binding

Disease: Limb-girdle Muscular Dystrophy, Type 1g

Research Articles on HNRPDL

1. A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with HNRPDL cdna clone

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>1 publications with HNRPDL and Embryonic Tissue