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HYAL3 cDNA Clone – Hyaluronoglucosaminidase 3 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277602

MBS1277602 is a cDNA clone targeting HYAL3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HYAL3, cDNA Clone
Full Product Name
HYAL3 cDNA Clone
Product Gene Name
HYAL3 cdna clone
Sequence
atgaccacgc aactgggccc agccctggtg ctgggggtgg ccctgtgcct gggttgtggc cagcccctac cacaggtccc tgaacgcccc ttctctgtgc tgtggaatgt accctcagca cactgtgagg cccgctttgg tgtgcacctg ccactcaatt ctctgggcat catagccaac cgtggccagc attttcacgg tcagaacatg accattttct acaagaacca actcggcctc tatccctact ttggacccag gggcacagct cacaatgggg gcatccccca ggctttgccc cttgaccgcc acctggcact ggctgcctac cagatccacc acagcctgag acctggcttt gctggcccag cagtgctgga ttgggaggag tggtgtccac tctgggctgg gaactggggc cgccgccgag cttatcaggc agcctcttgg gcttgggcac agcaggtatt ccctgacctg gaccctcagg agcagctcta caaggcctat actggctttg agcaggcggc ccgtgcactg atggaggata cgctgcgggt ggcccaggca ctacggcccc atggactctg gggcttctat cactacccag cctgtggcaa tggctggcat agtatggctt ccaactatac cggccgctgc catgcagcca cccttgcccg caacactcaa ctgcattggc tctgggccgc ctccagtgcc ctcttcccca gcatctacct cccacccagg ctgccacctg cccaccacca ggcctttgtc cgacatcgcc tggaggaggc cttccgtgtg gcccttgttg ggcaccgaca tcccctgcct gtcctggcct atgtccgcct cacacaccgg agatctggga ggttcctgtc ccaggatgac cttgtgcagt ccattggtgt gagtgcagca ctaggggcag ccggcgtggt gctctggggg gacctgagcc tctccagctc tgaggaggag tgctggcatc tccatgacta cctggtggac accttgggcc cctatgtgat caatgtgacc agggcagcga tggcctgcag tcaccagcgg tgccatggcc acgggcgctg tgcccggcga gatccaggac agatggaagc ctttctacac ctgtggccag acggcagcct tggagattgg aagtccttca gctgccactg ttactggggc tgggctggcc ccacctgcca ggagcccagg cctgggccta aagaagcagt ataa
Molecular Weight
15,865 Da
OMIM
604038
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HYAL3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HYAL3. It may not necessarily be applicable to this product.

NCBI GI #
13543476
NCBI GeneID
8372
NCBI Accession #
BC005896
UniProt Secondary Accession #
O60540; Q8NFK2; Q8NFK3; Q8NFK4; Q96E56; Q9BRW9
UniProt Related Accession #
O43820
NCBI Official Full Name
Homo sapiens hyaluronoglucosaminidase 3, mRNA
NCBI Official Synonym Full Names
hyaluronoglucosaminidase 3
NCBI Official Symbol
HYAL3
NCBI Official Synonym Symbols
LUCA3; HYAL-3; LUCA-3
UniProt Protein Name
Hyaluronidase-3
UniProt Synonym Protein Names
Hyaluronoglucosaminidase-3; Lung carcinoma protein 3; LuCa-3
UniProt Gene Name
HYAL3
UniProt Synonym Gene Names
LUCA3; Hyal-3; LuCa-3
UniProt Entry Name
HYAL3_HUMAN
NCBI Protein Information
hyaluronidase-3

NCBI Summary for HYAL3

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
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UniProt Comments for HYAL3

HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Protein type: Secreted, signal peptide; Hydrolase; Secreted; EC 3.2.1.35

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cytoplasmic vesicle; lysosome

Molecular Function: hyaluronoglucuronidase activity; hyalurononglucosaminidase activity; protein binding; viral receptor activity

Biological Process: cartilage development; hyaluronan catabolic process; inflammatory response; response to antibiotic; response to virus
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Research Articles on HYAL3

1. the relative expression of hyalurosome (CD44, HAS3, HB-EGF) genes was found to be reduced in patients prior to topical treatment and to be notably increased following treatment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HYAL3 cdna clone

 Products by Pathway  Pathway Diagram
 Chondroitin Sulfate Degradation Pathway antibodies  Chondroitin Sulfate Degradation Pathway Diagram
 Chondroitin Sulfate Degradation Pathway antibodies  Chondroitin Sulfate Degradation Pathway Diagram
 Dermatan Sulfate Degradation Pathway antibodies  Dermatan Sulfate Degradation Pathway Diagram
 Dermatan Sulfate Degradation Pathway antibodies  Dermatan Sulfate Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram

Diseases associated with HYAL3 cdna clone

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with HYAL3 and Disease Models, Animal
 Necrosis Antibodies  >2 publications with HYAL3 and Necrosis
 Genital Diseases, Male Antibodies  >1 publications with HYAL3 and Genital Diseases, Male
 Liver Neoplasms Antibodies  >1 publications with HYAL3 and Liver Neoplasms
 Kidney Diseases Antibodies  >1 publications with HYAL3 and Kidney Diseases
 Inflammation Antibodies  >1 publications with HYAL3 and Inflammation

Organs/Tissues associated with HYAL3 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with HYAL3 and Lung
 Kidney Antibodies  >4 publications with HYAL3 and Kidney
 Blood Antibodies  >3 publications with HYAL3 and Blood
 Placenta Antibodies  >2 publications with HYAL3 and Placenta
 Embryonic Tissue Antibodies  >2 publications with HYAL3 and Embryonic Tissue
 Testis Antibodies  >1 publications with HYAL3 and Testis
 Brain Antibodies  >1 publications with HYAL3 and Brain
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