Human IGF2BP3 cDNA Clone Expression Plasmid – Cat# MBS1276887

IGF2BP3 cDNA Clone – Insulin-Like Growth Factor 2 Mrna Binding Protein 3 (Human)

Name: IGF2BP3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276887
Price: 670 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276887

MBS1276887 is a cDNA clone targeting IGF2BP3. More details

$670 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IGF2BP3, cDNA Clone

Full Product Name

IGF2BP3 cDNA Clone

Product Gene Name

IGF2BP3 cdna clone

Sequence

atgaacaaac tgtatatcgg aaacctcagc gagaacgccg ccccctcgga cctagaaagt atcttcaagg acgccaagat cccggtgtcg ggacccttcc tggtgaagac tggctacgcg ttcgtggact gcccggacga gagctgggcc ctcaaggcca tcgaggcgct ttcaggtaaa atagaactgc acgggaaacc catagaagtt gagcactcgg tcccaaaaag gcaaaggatt cggaaacttc agatacgaaa tatcccgcct catttacagt gggaggtgct ggatagttta ctagtccagt atggagtggt ggagagctgt gagcaagtga acactgactc ggaaactgca gttgtaaatg taacctattc cagtaaggac caagctagac aagcactaga caaactgaat ggatttcagt tagagaattt caccttgaaa gtagcctata tccctgatga aatggccgcc cagcaaaacc ccttgcagca gccccgaggt cgccgggggc ttgggcagag gggctcctca aggcaggggt ctccaggatc cgtatccaag cagaaaccat gtgatttgcc tctgcgcctg ctggttccca cccaatttgt tggagccatc ataggaaaag aaggtgccac cattcggaac atcaccaaac agacccagtc taaaatcgat gtccaccgta aagaaaatgc gggggctgct gagaagtcga ttactatcct ctctactcct gaaggcacct ctgcggcttg taagtctatt ctggagatta tgcataagga agctcaagat ataaaattca cagaagagat ccccttgaag attttagctc ataataactt tgttggacgt cttattggta aagaaggaag aaatcttaaa aaaattgagc aagacacaga cactaaaatc acgatatctc cattgcagga attgacgctg tataatccag aacgcactat tacagttaaa ggcaatgttg agacatgtgc caaagctgag gaggagatca tgaagaaaat cagggagtct tatgaaaatg atattgcttc tatgaatctt caagcacatt taattcctgg attaaatctg aacgccttgg gtctgttccc acccacttca gggatgccac ctcccacctc agggccccct tcagccatga ctcctcccta cccgcagttt gagcaatcag aaacggagac tgttcatctg tttatcccag ctctatcagt cggtgccatc atcggcaagc agggccagca catcaagcag ctttctcgct ttgctggagc ttcaattaag attgctccag cagaagcacc agatgctaaa gtgaggatgg tgattatcac tggaccacca gaggctcagt tcaaggctca gggaagaatt tatggaaaaa ttaaagaaga aaactttgtt agtcctaaag aagaggtgaa acttgaagct catatcagag tgccatcctt tgctgctggc agagttattg gaaaaggagg caaaacggtg aatgaacttc agaatttgtc aagtgcagaa gttgttgtcc ctcgtgacca gacacctgat gagaatgacc aagtggttgt caaaataact ggtcacttct atgcttgcca ggttgcccag agaaaaattc aggaaattct gactcaggta aagcagcacc aacaacagaa ggctctgcaa agtggaccac ctcagtcaag acggaagtaa

Molecular Weight

21,630 Da

OMIM

608259

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IGF2BP3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF2BP3. It may not necessarily be applicable to this product.

NCBI GI #

40807046

NCBI GeneID

10643

NCBI Accession #

BC065269

UniProt Secondary Accession #

Q63HM0; Q6MZZ2; Q86VB1; A0A4Z5

UniProt Related Accession #

O00425

NCBI Official Full Name

Homo sapiens insulin-like growth factor 2 mRNA binding protein 3, mRNA

NCBI Official Synonym Full Names

insulin like growth factor 2 mRNA binding protein 3

NCBI Official Symbol

IGF2BP3

NCBI Official Synonym Symbols

KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3

UniProt Protein Name

Insulin-like growth factor 2 mRNA-binding protein 3

UniProt Synonym Protein Names

IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3

Protein Family

Insulin-like growth factor 2 mRNA-binding protein

UniProt Gene Name

IGF2BP3

UniProt Synonym Gene Names

IMP3; KOC1; VICKZ3; IGF2 mRNA-binding protein 3; IMP-3; hKOC

UniProt Entry Name

IF2B3_HUMAN

NCBI Protein Information

insulin-like growth factor 2 mRNA-binding protein 3

NCBI Summary for IGF2BP3

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

UniProt Comments for IGF2BP3

IGF2BP3: RNA-binding protein that act as a regulator of mRNA translation and stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binds to sequences in the 3'-UTR of CD44 mRNA. Belongs to the RRM IMP/VICKZ family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA-binding; Translation

Chromosomal Location of Human Ortholog: 7p11

Cellular Component: cytoplasm; cytosol

Molecular Function: mRNA 3'-UTR binding; mRNA 5'-UTR binding; protein binding; RNA binding; translation regulator activity

Biological Process: anatomical structure morphogenesis; gene expression; negative regulation of translation; regulation of cytokine biosynthetic process; translation

Research Articles on IGF2BP3

1. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IGF2BP3 cdna clone

Products by Pathway	Pathway Diagram
Binding Of RNA By Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Pathway antibodies	Binding Of RNA By Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram

Diseases associated with IGF2BP3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>13 publications with IGF2BP3 and Neoplasms
Carcinoma Antibodies	>11 publications with IGF2BP3 and Carcinoma
Pancreatic Neoplasms Antibodies	>2 publications with IGF2BP3 and Pancreatic Neoplasms
Liver Diseases Antibodies	>2 publications with IGF2BP3 and Liver Diseases
Ovarian Neoplasms Antibodies	>2 publications with IGF2BP3 and Ovarian Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with IGF2BP3 and Neoplasms, Experimental
Recurrence Antibodies	>1 publications with IGF2BP3 and Recurrence
Liver Neoplasms Antibodies	>1 publications with IGF2BP3 and Liver Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with IGF2BP3 and Neoplasm Metastasis
Abnormalities, Multiple Antibodies	>1 publications with IGF2BP3 and Abnormalities, Multiple

Organs/Tissues associated with IGF2BP3 cdna clone

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>2 publications with IGF2BP3 and Pancreas
Blood Antibodies	>2 publications with IGF2BP3 and Blood
Liver Antibodies	>2 publications with IGF2BP3 and Liver
Brain Antibodies	>2 publications with IGF2BP3 and Brain
Placenta Antibodies	>2 publications with IGF2BP3 and Placenta
Embryonic Tissue Antibodies	>2 publications with IGF2BP3 and Embryonic Tissue
Lung Antibodies	>1 publications with IGF2BP3 and Lung
Uterus Antibodies	>1 publications with IGF2BP3 and Uterus
Lymph Antibodies	>1 publications with IGF2BP3 and Lymph
Bone Marrow Antibodies	>1 publications with IGF2BP3 and Bone Marrow