Human IGSF8 cDNA Clone Expression Plasmid – Cat# MBS1273931

IGSF8 cDNA Clone – Immunoglobulin Superfamily, Member 8 (Human)

Name: IGSF8 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273931
Price: 710 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273931

MBS1273931 is a cDNA clone targeting IGSF8. More details

$710 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IGSF8, cDNA Clone

Full Product Name

IGSF8 cDNA Clone

Product Gene Name

IGSF8 cdna clone

Sequence

atgggcgccc tcaggcccac gctgctgccg ccttcgctgc cgctgctgct gctgctaatg ctaggaatgg gatgctgggc ccgggaggtg ctggtccccg aggggccctt gtaccgcgtg gctggcacag ctgtctccat ctcctgcaat gtgaccggct atgagggccc tgcccagcag aacttcgagt ggttcctgta taggcccgag gccccagata ctgcactggg cattgtcagt accaaggata cccagttctc ctatgctgtc ttcaagtccc gagtggtggc gggtgaggtg caggtgcagc gcctacaagg tgatgccgtg gtgctcaaga ttgcccgcct gcaggcccag gatgccggca tttatgagtg ccacaccccc tccactgata cccgctacct gggcagctac agcggcaagg tggagctgag agttcttcca gatgtcctcc aggtgtctgc tgccccccca gggccccgag gccgccaggc cccaacctca cccccacgca tgacggtgca tgaggggcag gagctggcac tgggctgcct ggcgaggaca agcacacaga agcacacaca cctggcagtg tcctttgggc gatctgtgcc cgaggcacca gttgggcggt caactctgca ggaagtggtg ggaatccggt cagacttggc cgtggaggct ggagctccct atgctgagcg attggctgca ggggagcttc gtctgggcaa ggaagggacc gatcggtacc gcatggtagt agggggtgcc caggcagggg acgcaggcac ctaccactgc actgccgctg agtggattca ggatcctgat ggcagctggg cccagattgc agagaaaagg gccgtcctgg cccacgtgga tgtgcagacg ctgtccagcc agctggcagt gacagtgggg cctggtgaac gtcggatcgg cccaggggag cccttggaac tgctgtgcaa tgtgtcaggg gcacttcccc cagcaggccg tcatgctgca tactctgtag gttgggagat ggcacctgcg ggggcacctg ggcccggccg cctggtagcc cagctggaca cagagggtgt gggcagcctg ggccctggct atgagggccg acacattgcc atggagaagg tggcatccag aacataccgg ctacggctag aggctgccag gcctggtgat gcgggcacct accgctgcct cgccaaagcc tatgttcgag ggtctgggac ccggcttcgt gaagcagcca gtgcccgttc ccggcctctc cctgtacatg tgcgggagga aggtgtggtg ctggaggctg tggcatggct agcaggaggc acagtgtacc gcggggagac tgcctccctg ctgtgcaaca tctctgtgcg gggtggcccc ccaggactgc ggctggccgc cagctggtgg gtggagcgac cagaggacgg agagctcagc tctgtccctg cccagctggt gggtggcgta ggccaggatg gtgtggcaga gctgggagtc cggcctggag gaggccctgt cagcgtagag ctggtggggc cccgaagcca tcggctgaga ctacacagct tggggcccga ggatgaaggc gtgtaccact gtgcccccag cgcctgggtg cagcatgccg actacagctg gtaccaggcg ggcagtgccc gctcagggcc tgttacagtc tacccctaca tgcatgccct ggacacccta tttgtgcctc tgctggtggg tacaggggtg gccctagtca ctggtgccac tgtccttggt accatcactt gctgcttcat gaagaggctt cgaaaacggt ga

Molecular Weight

55,808 Da

OMIM

606644

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IGSF8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGSF8. It may not necessarily be applicable to this product.

NCBI GI #

31753232

NCBI GeneID

93185

NCBI Accession #

BC053881

UniProt Secondary Accession #

Q8NG09; Q96DP4; Q9BTG9

UniProt Related Accession #

Q969P0

NCBI Official Full Name

Homo sapiens immunoglobulin superfamily, member 8, mRNA

NCBI Official Synonym Full Names

immunoglobulin superfamily member 8

NCBI Official Symbol

IGSF8

NCBI Official Synonym Symbols

EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1

UniProt Protein Name

Immunoglobulin superfamily member 8

UniProt Synonym Protein Names

CD81 partner 3; Glu-Trp-Ile EWI motif-containing protein 2; EWI-2; Keratinocytes-associated transmembrane protein 4; KCT-4; LIR-D1; Prostaglandin regulatory-like protein; PGRL; CD_antigen: CD316

Protein Family

Immunoglobulin superfamily

UniProt Gene Name

IGSF8

UniProt Synonym Gene Names

CD81P3; EWI2; KCT4; IgSF8; EWI-2; KCT-4; PGRL

UniProt Entry Name

IGSF8_HUMAN

NCBI Protein Information

immunoglobulin superfamily member 8

NCBI Summary for IGSF8

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

UniProt Comments for IGSF8

IGSF8: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin- dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: integral to membrane; membrane

Molecular Function: protein binding

Research Articles on IGSF8

1. EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with IGSF8 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with IGSF8 and Neoplasms
Hepatitis Antibodies	>3 publications with IGSF8 and Hepatitis
Liver Diseases Antibodies	>1 publications with IGSF8 and Liver Diseases