Human IL18RAP cDNA Clone Expression Plasmid – Cat# MBS1277130

IL18RAP cDNA Clone – Interleukin 18 Receptor Accessory Protein (Human)

Name: IL18RAP cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1277130
Price: 690 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277130

MBS1277130 is a cDNA clone targeting IL18RAP. More details

$690 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL18RAP, cDNA Clone

Full Product Name

IL18RAP cDNA Clone

Product Gene Name

IL18RAP cdna clone

Sequence

ATGCTCTGTT TGGGCTGGAT ATTTCTTTGG CTTGTTGCAG GAGAGCGAAT TAAAGGATTT AATATTTCAG GTTGTTCCAC AAAAAAACTC CTTTGGACAT ATTCTACAAG GAGTGAAGAG GAATTTGTCT TATTTTGTGA TTTACCAGAG CCACAGAAAT CACATTTCTG CCACAGAAAT CGACTCTCAC CAAAACAAGT CCCTGAGCAC CTGCCCTTCA TGGGTAGTAA CGACCTATCT GATGTCCAAT GGTACCAACA ACCTTCGAAT GGAGATCCAT TAGAGGACAT TAGGAAAAGC TATCCTCACA TCATTCAGGA CAAATGTACC CTTCACTTTT TGACCCCAGG GGTGAATAAT TCTGGGTCAT ATATTTGTAG ACCCAAGATG ATTAAGAGCC CCTATGATGT AGCCTGTTGT GTCAAGATGA TTTTAGAAGT TAAGCCCCAG ACAAATGCAT CCTGTGAGTA TTCCGCATCA CATAAGCAAG ACCTACTTCT TGGGAGCACT GGCTCTATTT CTTGCCCCAG TCTCAGCTGC CAAAGTGATG CACAAAGTCC AGCGGTAACC TGGTACAAGA ATGGAAAACT CCTCTCTGTG GAAAGGAGCA ACCGAATCGT AGTGGATGAA GTTTATGACT ATCACCAGGG CACATATGTA TGTGATTACA CTCAGTCGGA TACTGTGAGT TCGTGGACAG TCAGAGCTGT TGTTCAAGTG AGAACCATTG TGGGAGACAC TAAACTCAAA CCAGATATTC TGGATCCTGT CGAGGACACA CTGGAAGTAG AACTTGGAAA GCCTTTAACT ATTAGCTGCA AAGCACGATT TGGCTTTGAA AGGGTCTTTA ACCCTGTCAT AAAATGGTAC ATCAAAGATT CTGACCTAGA GTGGGAAGTC TCAGTACCTG AGGCGAAAAG TATTAAATCC ACTTTAAAGG ATGAAATCAT TGAGCGTAAT ATCATCTTGG AAAAAGTCAC TCAGCGTGAT CTTCGCAGGA AGTTTGTTTG CTTTGTCCAG AACTCCATTG GAAACACAAC CCAGTCCGTC CAACTGAAAG AAAAGAGAGG AGTGGTGCTC CTGTACATCC TGCTTGGCAC CATCGGGACC CTGGTGGCCG TGCTGGCGGC GAGTGCCCTC CTCTACAGGC ACTGGATTGA AATAGTGCTG CTGTACCGGA CCTACCAGAG CAAGGATCAG ACGCTTGGGG ATAAAAAGGA TTTTGATGCT TTCGTATCCT ATGCAAAATG GAGCTCTTTT CCAAGTGAGG CCACTTCATC TCTGAGTGAA GAACACTTGG CCCTGAGCCT ATTTCCTGAT GTTTTAGAAA ACAAATATGG ATATAGCCTG TGTTTGCTTG AAAGAGATGT GGCTCCAGGA GGAGTGTATG CAGAAGACAT TGTGAGCATT ATTAAGAGAA GCAGAAGAGG AATATTTATC TTGAGCCCCA ACTATGTCAA TGGACCCAGT ATCTTTGAAC TACAAGCAGC AGTGAATCTT GCCTTGGATG ATCAAACACT GAAACTCATT TTAATTAAGT TCTGTTACTT CCAAGAGCCA GAGTCTCTAC CTCATCTCGT GAAAAAAGCT CTCAGGGTTT TGCCCACAGT TACTTGGAGA GGCTTAAAAT CAGTTCCTCC CAATTCTAGG TTCTGGGCCA AAATGCGCTA CCACATGCCT GTGAAAAACT CTCAGGGATT CACGTGGAAC CAGCTCAGAA TTACCTCTAG GATTTTTCAG TGGAAAGGAC TCAGTAGAAC AGAAACCACT GGGAGGAGCT CCCAGCCTAA GGAATGGTGA

Molecular Weight

51,945 Da

OMIM

604509

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL18RAP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL18RAP. It may not necessarily be applicable to this product.

NCBI GI #

115527605

NCBI GeneID

8807

NCBI Accession #

BC106765

UniProt Secondary Accession #

Q3KPE7; Q3KPE8; Q53TT4; Q53TU5; B2RPJ3

UniProt Related Accession #

O95256

NCBI Official Full Name

Homo sapiens interleukin 18 receptor accessory protein, mRNA

NCBI Official Synonym Full Names

interleukin 18 receptor accessory protein

NCBI Official Symbol

IL18RAP

NCBI Official Synonym Symbols

ACPL; CD218b; IL-1R7; IL18RB; CDw218b; IL-1R-7; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta

UniProt Protein Name

Interleukin-18 receptor accessory protein

UniProt Synonym Protein Names

Accessory protein-like; AcPL; CD218 antigen-like family member B; CDw218b; IL-1R accessory protein-like; IL-1RAcPL; Interleukin-1 receptor 7; IL-1R-7; IL-1R7; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; IL-18R-beta; IL-18Rbeta; CD_antigen: CD218b

Protein Family

Interleukin-18 receptor accessory protein

UniProt Gene Name

IL18RAP

UniProt Synonym Gene Names

IL1R7; IL-18 receptor accessory protein; IL-18RAcP; AcPL; IL-1RAcPL; IL-1R-7; IL-1R7; IL-18R-beta; IL-18Rbeta

UniProt Entry Name

I18RA_HUMAN

NCBI Protein Information

interleukin-18 receptor accessory protein

NCBI Summary for IL18RAP

The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

UniProt Comments for IL18RAP

IL18RAP: Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex. Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: plasma membrane

Molecular Function: receptor activity

Biological Process: cell surface receptor linked signal transduction; immune response; inflammatory response

Research Articles on IL18RAP

1. This meta-analysis provides robust estimates that IL18RAP rs917997 and chemokine (C-C motif) receptor 3 rs6441961 are potential risk factors for celiac disease in European populations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL18RAP cdna clone

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
IL12 Signaling Mediated By STAT4 Pathway antibodies	IL12 Signaling Mediated By STAT4 Pathway Diagram
IL12-mediated Signaling Events Pathway antibodies	IL12-mediated Signaling Events Pathway Diagram
IL23-mediated Signaling Events Pathway antibodies	IL23-mediated Signaling Events Pathway Diagram

Diseases associated with IL18RAP cdna clone

Disease Name	Pubmed Publications
Inflammation Antibodies	>9 publications with IL18RAP and Inflammation
Cardiovascular Diseases Antibodies	>6 publications with IL18RAP and Cardiovascular Diseases
Inflammatory Bowel Diseases Antibodies	>6 publications with IL18RAP and Inflammatory Bowel Diseases
Colitis Antibodies	>3 publications with IL18RAP and Colitis
Colitis, Ulcerative Antibodies	>3 publications with IL18RAP and Colitis, Ulcerative
Atherosclerosis Antibodies	>2 publications with IL18RAP and Atherosclerosis
Necrosis Antibodies	>2 publications with IL18RAP and Necrosis
Liver Diseases Antibodies	>1 publications with IL18RAP and Liver Diseases
Prenatal Exposure Delayed Effects Antibodies	>1 publications with IL18RAP and Prenatal Exposure Delayed Effects
Kidney Diseases Antibodies	>1 publications with IL18RAP and Kidney Diseases

Organs/Tissues associated with IL18RAP cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>19 publications with IL18RAP and Blood
Brain Antibodies	>4 publications with IL18RAP and Brain
Kidney Antibodies	>2 publications with IL18RAP and Kidney
Spleen Antibodies	>1 publications with IL18RAP and Spleen
Liver Antibodies	>1 publications with IL18RAP and Liver