Human INTS3 cDNA Clone Expression Plasmid – Cat# MBS1274044

INTS3 cDNA Clone – Integrator Complex Subunit 3 (Human)

Name: INTS3 cDNA Clone; Integrator Complex Subunit 3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274044
Price: 1310 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274044

MBS1274044 is a cDNA clone targeting INTS3. More details

$1310 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

INTS3, cDNA Clone

Full Product Name

INTS3 cDNA Clone

Product Gene Name

INTS3 cdna clone

Sequence

ATGGAGTTGC AGAAGGGAAA AGGGGCGGCA GCAGCAGCAG CTGCTTCGGG AGCAGCGGGA GGTGGAGGAG GAGGAGCGGG AGCAGGAGCC CCAGGAGGGG GGAGGCTGCT ACTTTCAACC AGTTTGGATG CCAAGGATGA GTTAGAGGAG AGATTGGAAA GGTGTATGAG CATTGTGACA TCGATGACTG CTGGTGTCTC GGAGAGAGAA GCCAATGATG CCCTCAATGC GTATGTGTGC AAAGGCCTCC CCCAGCATGA AGAAATCTGC CTGGGCCTGT TTACTCTCAT CCTCACTGAA CCTGCCCAAG CCCAGAAGTG TTACCGGGAC TTAGCTCTGG TGAGTCGTGA TGGCATGAAT ATTGTCCTGA ATAAAATCAA CCAGATACTT ATGGAGAAGT ACCTGAAGCT GCAGGATACC TGCCGTACTC AGTTGGTGTG GTTGGTACGG GAACTGGTGA AGAGTGGGGT TCTGGGAGCC GATGGTGTTT GTATGACGTT TATGAAGCAG ATTGCAGGTG GAGATGTTAC AGCCAAAAAT ATCTGGTTGG CAGAAAGTGT TCTGGATATC CTGACAGAGC AAAGGGAGTG GGTCCTGAAG AGCAGCATCC TCATTGCCAT GGCTGTTTAC ACGTACCTCC GCCTCATCGT GGACCACCAT GGGACTGCCC AGCTCCAGGC CCTGCGACAG AAGGAAGTAG ACTTCTGCAT CTCACTGCTT CGGGAACGGT TCATGGAATG TCTGATGATT GGTCGGGATC TCGTAAGACT ACTTCAGAAT GTTGCTAGGA TACCAGAATT TGAACTGCTT TGGAAAGATA TTATCCATAA TCCTCAGGCC TTGAGTCCTC AGTTCACAGG TATCCTACAG CTTCTTCAGT CAAGAACATC CCGAAAATTC CTAGCATGTC GTCTAACCCC GGACATGGAG ACTAAACTCC TCTTCATGAC ATCCCGGGTG CGATTTGGTC AACAAAAGCG ATACCAAGAT TGGTTCCAGC GCCAGTACCT GTCAACTCCA GATAGTCAGT CTCTGCGCTG TGACCTCATT CGCTACATCT GTGGGGTAGT CCACCCTTCT AATGAAGTAC TGAGTTCAGA TATCTTGCCC CGGTGGGCCA TCATTGGTTG GCTCCTGACA ACGTGCACGT CAAATGTCGC TGCCTCCAAT GCCAAGCTGG CTTTGTTTTA TGACTGGCTG TTCTTTAGTC CAGACAAGGA TAGCATTATG AACATAGAAC CAGCCATCCT GGTCATGCAC CACTCCATGA AGCCCCACCC AGCCATCACT GCCACACTCC TGGACTTCAT GTGCCGCATC ATTCCCAACT TCTATCCACC ATTGGAGGGC CACGTGCGGC AGGGTGTCTT TTCCTCCCTC AACCACATTG TGGAGAAACG GGTCTTGGCA CACCTAGCTC CCCTGTTTGA CAACCCTAAG TTGGATAAGG AGCTGCGGGC AATGCTGAGA GAGAAGTTTC CTGAGTTCTG CAGCTCACCC TCCCCACCTG TGGAAGTCAA AATTGAGGAG CCAGTTTCCA TGGAGATGGA CAACCATATG TCGGATAAGG ATGAGAGTTG CTATGACAAT GCAGAGGCAG CCTTCAGTGA CGATGAAGAG GATCTCAACA GCAAAGGAAA GAAGAGGGAG TTTCGCTTCC ACCCTATCAA GGAGACAGTT GTGGAGGAGC CAGTTGATAT CACCCCTTAC CTTGACCAGT TGGATGAGTC CCTGAGGGAC AAAGTACTCC AGCTACAGAA GGGGAGTGAT ACGGAGGCCC AGTGTGAGGT CATGCAGGAA ATTGTGGACC AGGTCCTGGA GGAAGACTTT GACTCGGAGC AGCTGTCTGT CCTTGCTTCC TGCCTACAGG AGCTCTTCAA GGCCCACTTT CGAGGGGAGG TCCTGCCTGA GGAGATTACT GAGGAGTCCC TGGAGGAGTC TGTAGGAAAG CCTCTGTACC TAATATTTAG GAACCTATGT CAGATGCAGG AAGACAACAG CAGCTTCTCT CTACTTCTAG ACCTTCTCTC CGAGCTATAT CAGAAGCAGC CCAAGATTGG CTACCACCTG CTCTACTACC TGAGGGCCAG CAAAGCCGCC GCAGGGAAGA TGAACCTGTA CGAGTCATTT GCCCAGGCTA CCCAGCTGGG CGATCTGCAC ACCTGCCTGA TGATGGACAT GAAGGCCTGC CAGGAGGACG ATGTGCGGCT CCTGTGCCAC CTCACGCCCT CCATCTACAC AGAGTTTCCA GATGAAACCT TGAGGAGCGG AGAGCTGCTG AACATGATCG TGGCTGTTAT TGACTCTGCA CAGCTCCAGG AGCTGGTCTG CCACGTGATG ATGGGTAACC TGGTTATGTT TCGAAAAGAC TCAGTTCTCA ACATACTCAT TCAGAGCCTA GACTGGGAGA CCTTTGAGCA GTATTGTGCC TGGCAGCTCT TTCTGGCCCA CAATATTCCC CTGGAGACCA TAATCCCCAT CCTGCAGCAC CTCAAATACA AGGAGCACCC AGAGGCCCTG TCCTGCCTAC TGCTTCAACT CCGAAGAGAA AAGCCCAGCG AGGAGATGGT GAAGATGGTG CTGAGCCGGC CCTGCCATCC TGACGACCAG TTCACCACCA GCATCCTGCG GCACTGGTGC ATGAAACATG ACGAGCTGCT GGCCGAGCAC ATCAAGTCCC TGCTCATCAA GAACAACAGC CTGCCTCGCA AGAGACAGAG CCTGAGGAGC TCTAGCAGCA AGCTGGCCCA GCTGACTCTG GAGCAGATCC TGGAGCACTT GGACAATCTG CGGCTCAACC TGACCAACAC CAAGCAGAAC TTTTTTAGCC AGACGCCAAT TCTCCAGGCG CTGCAGCATG TCCAAGCGAG CTGTGACGAA GCCCACAAGA TGAAATTCAG TGATCTCTTC TCCCTGGCGG AGGAATATGA GGACTCTTCC ACCAAGCCAC CCAAGAGCCG GCGAAAAGCA GCTCTGTCCA GCCCTCGAAG TCGAAAGAAT GCCACACAGC CCCCCAATGC CGAAGAAGAG TCGGGCTCCA GCAGTGCTTC AGAAGAGGAA GACACGAAAC CGAAGCCTAC CAAGCGGAAA CGAAAAGGGT CCTCTGCAGT GGGCTCTGAC AGTGACTGA

Molecular Weight

63,586 Da

OMIM

611347

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of INTS3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INTS3. It may not necessarily be applicable to this product.

NCBI GI #

95132373

NCBI GeneID

65123

NCBI Accession #

BC116458

UniProt Secondary Accession #

Q4G0E5; Q5VUQ5; Q5VUQ6; Q5VUR0; Q5VUR1; Q68DJ1; Q69YR5; A8K1W0; B4DQC8; B4E3U9; D3DV57

UniProt Related Accession #

Q68E01

NCBI Official Full Name

Homo sapiens integrator complex subunit 3, mRNA

NCBI Official Synonym Full Names

integrator complex subunit 3

NCBI Official Symbol

INTS3

NCBI Official Synonym Symbols

INT3; SOSSA; SOSS-A; C1orf60; C1orf193

UniProt Protein Name

Integrator complex subunit 3

UniProt Synonym Protein Names

SOSS complex subunit A; Sensor of single-strand DNA complex subunit A; SOSS-A; Sensor of ssDNA subunit A

Protein Family

Integrator complex

UniProt Gene Name

INTS3

UniProt Synonym Gene Names

C1orf193; C1orf60; Int3; SOSS-A; Sensor of ssDNA subunit A

UniProt Entry Name

INT3_HUMAN

NCBI Protein Information

integrator complex subunit 3

NCBI Summary for INTS3

The protein encoded by this gene can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs. [provided by RefSeq, May 2016]

UniProt Comments for INTS3

INTS3: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 3 family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: integrator complex; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: DNA repair; mitotic cell cycle checkpoint; response to DNA damage stimulus; response to ionizing radiation; snRNA processing; snRNA transcription from RNA polymerase II promoter

Research Articles on INTS3

1. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with INTS3 cdna clone

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with INTS3 and Breast Neoplasms
Liver Diseases Antibodies	>1 publications with INTS3 and Liver Diseases

Organs/Tissues associated with INTS3 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with INTS3 and Kidney
Liver Antibodies	>1 publications with INTS3 and Liver