Human INTS4 cDNA Clone Expression Plasmid – Cat# MBS1267256

INTS4 cDNA Clone – Integrator Complex Subunit 4 (Human)

Name: INTS4 cDNA Clone; Integrator Complex Subunit 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267256
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267256

MBS1267256 is a cDNA clone targeting INTS4. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

INTS4, cDNA Clone

Full Product Name

INTS4 cDNA Clone

Product Gene Name

INTS4 cdna clone

Sequence

atggcggcgc accttaagaa gcgggtttat gaggaattca cgaaagtggt tcagccacag gaggaaattg ctactaagaa actccgacta acaaaaccaa gtaaatctgc agcactccac atagatctgt gtaaagctac ctccccagca gatgctttgc aatacttgct ccagtttgcc aggaagcctg tcgaggcgga aagcgtagag ggagtagtca ggattctctt ggaacattat tacaaggaga atgatccatc tgtgagactg aaaattgcat cattgttggg tttattatca aagacagcag gattttcacc agactgcatt atggatgatg ccatcaacat cctgcagaat gaaaagtctc atcaagtcct agctcaactg ctggatactt tgcttgcaat tggcactaag ctaccagaga atcaagctat ccaaatgcga ttagttgatg tggcctgcaa gcatctgaca gatacgtctc atggtgtaag aaataagtgc ctgcagttac ttggcaatct tggctctttg gagaaaagtg tcacaaaaga tgcagaaggc ctagctgcca gagatgtcca gaagattata ggggattact tcagtgacca agacccacgt gtcagaacag cagctataaa agccatgttg cagctccatg aaagaggact gaaattacac caaacaattt ataatcaggc ctgtaaatta ctctctgatg actatgaaca agtgcgcagt gctgcagtcc agcttatctg ggtcgtcagt cagctctatc ctgaaagcat tgtcccaatt ccttcttcta atgaagaaat acgcttagtt gatgatgcgt ttggcaaaat ttgtcacatg gtcagtgatg gctcttgggt ggttcgtgtt caggcagcaa aactgttggg ctctatggag caagtcagtt ctcatttctt ggagcagacc cttgacaaga agctgatgtc agatctgagg aggaaacgta ctgcacatga gcgtgccaag gaactttaca gttcggggga gttttccagt ggcagaaagt ggggagatga tgctcccaag gaagaagtag ataccggggc tgtgaacttg attgagtcag gagcttgtgg agcttttgtt catgggttgg aagatgagat gtatgaggtt cgtattgctg ctgtggaggc cctctgcatg ttggcccagt cttcaccctc ttttgctgag aagtgccttg atttcctagt tgacatgttc aacgatgaaa ttgaggaagt acgtctgcag tctatacata ccatgagaaa aatctctaac aacatcaccc tccgagaaga tcagcttgac actgtcctgg ctgtgctaga ggattcatcc agagatattc gagaggctct tcatgaactc ttatgctgta ctaatgtttc aaccaaagaa gggattcatc ttgcattggt ggagctgctg aaaaatttaa ccaagtaccc tactgatagg gactccatat ggaagtaa

Molecular Weight

38,117 Da

OMIM

611348

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of INTS4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INTS4. It may not necessarily be applicable to this product.

NCBI GI #

40226273

NCBI GeneID

92105

NCBI Accession #

BC009995

UniProt Secondary Accession #

Q2YD62; Q6PJG4; Q7Z4E7; Q96G32; Q96GA1; Q9BRC0

UniProt Related Accession #

Q96HW7

NCBI Official Full Name

Homo sapiens integrator complex subunit 4, mRNA

NCBI Official Synonym Full Names

integrator complex subunit 4

NCBI Official Symbol

INTS4

NCBI Official Synonym Symbols

INT4; MST093

UniProt Protein Name

Integrator complex subunit 4

Protein Family

Integrator complex

UniProt Gene Name

INTS4

UniProt Synonym Gene Names

Int4

UniProt Entry Name

INT4_HUMAN

NCBI Protein Information

integrator complex subunit 4

NCBI Summary for INTS4

INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

UniProt Comments for INTS4

INT4: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 4 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 11q14.1

Cellular Component: integrator complex; nucleoplasm

Molecular Function: protein binding

Biological Process: snRNA processing; snRNA transcription from RNA polymerase II promoter

Research Articles on INTS4

1. findings demonstrate that the integrator complex is essential for snRNA maturation and Cajal body homeostasis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with INTS4 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1 publications with INTS4 and Brain