Human IQSEC1 cDNA Clone Expression Plasmid – Cat# MBS1275146

IQSEC1 cDNA Clone – Iq Motif and Sec7 Domain 1 (Human)

Name: IQSEC1 cDNA Clone; Iq Motif and Sec7 Domain 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275146
Price: 910 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275146

MBS1275146 is a cDNA clone targeting IQSEC1. More details

$910 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IQSEC1, cDNA Clone

Full Product Name

IQSEC1 cDNA Clone

Product Gene Name

IQSEC1 cdna clone

Sequence

atgctagaac gaaagtatgg ggggcgcctg gtaacccgcc atgcggcccg caccatccag acggcgtttc gccagtacca gatgaacaag aacttcgagc gcttgcgcag ctccatgtca gagaaccgca tgtcacgccg gattgtgctg tccaacatga ggatgcagtt ctcctttgag gggcctgaga aagtgcacag ctcctacttc gaggggaagc aggtctcagt gactaacgac ggctcccagc tgggagccct ggtgtcccct gagtgtggtg acctcagcga gcccaccacc ctcaagtctc cggccccctc cagtgacttt gcggacgcca tcaccgagct ggaggacgcc ttctctaggc aagtgaaatc actggccgag tccatcgacg atgccctcaa ctgccgcagc ctgcacactg aggaggcacc ggccctggat gcggcgcggg cccgggacac cgaaccccag acagccctgc acggcatgga ccaccgcaaa ctggacgaga tgacggcctc gtacagtgat gtcaccctgt acatcgatga ggaggagctg tcgccccctc tgcccctctc gcaggcaggg gaccggccgt ccagcaccga gtcggacctg cggctacggg ctgggggcgc agccccagac tactgggccc tggcccacaa agaggacaag gctgacacgg acacgagctg ccggagcacg ccgtcgctgg agcggcagga gcagcggctg cgggtggagc atctgccgct gctcaccatc gagccaccca gcgacagctc tgtggacctt agtgaccgct cggagcgggg gtcactcaag aggcagagtg cttacgagcg cagccttggc gggcagcagg gcagtcccaa gcatggtccc cacagcggcg cccccaagag cctcccccgg gaggagcctg agttgcggcc ccggcccccc aggcccctgg acagccactt ggccatcaat ggctcagcca accggcagag caagtctgag tcggactact cagacggtga caatgacagc atcaacagca cgtccaactc caacgatacc atcaactgca gctccgagtc atcgtcccgt gacagcctgc gggagcagac gctcagcaag cagacctacc acaaggaggc ccgcaacagc tgggactcgc ctgcctttag caacgatgtc atccgcaaga ggcactaccg catcggcctg aacctcttca acaagaagcc tgagaaggga gtccagtacc tcatcgagcg tggctttgtg cccgacacgc ccgtcggggt ggcccacttc ctgctgcagc gcaagggcct cagccggcag atgatcggcg agttcctggg caaccggcag aagcagttca accgtgacgt gctcgactgc gtcgtggacg agatggactt ctctaccatg gagctggatg aggccctcag gaaattccag gcgcacatcc gtgtccaagg ggaggctcag aaagtggagc ggctcataga ggcgttcagc cagcgctact gcatctgcaa ccctggggtg gtgcggcaat tccggaaccc agacaccatt ttcatcctgg ccttcgccat catcctgctg aacaccgaca tgtacagccc caatgtcaag cccgagcgga aaatgaagct agaggacttc atcaagaacc tccgaggtgt ggacgatggt gaggacattc cccgtgagat gctgatgggg atctatgaac ggatccgtaa gcgagagcta aagaccaatg aggaccatgt gtcccaggtg cagaaggtgg agaagctcat tgtggggaaa aagccgatcg gatccctgca tcccgggctc ggctgtgtgc tctctctgcc ccaccgtcgg ttggtctgct actgccggct ctttgaggtt ccagacccaa acaagcccca gaaactcgga ctacaccagc gagaaatctt cctgttcaac gacctcctgg tggtcaccaa gatcttccag aagaagaaga actcggtgac gtacagcttc cgacagtcct tctccttgta cggcatgcag gtcctgctct tcgagaacca gtactacccc aatggcatcc ggctcacctc gtctgtcccc ggagcagata tcaaagtgtt aataaacttc aacgccccca accctcaaga ccggaagaaa ttcaccgatg acctgcggga gtccattgcg gaagtccaag agatggagaa gcacaggata gagtcggagc tcgagaagca gaaaggcgtc gtgcggccca gcatgtccca gtgctctagc ctcaaaaagg agtcgggcaa cggaacactg agccgggcct gcctggacga cagctatgcc agcggtgagg gcctcaagcg cagcgccctc agcagctccc tgcgggacct ctcggaagcc ggggtccatc attag

Molecular Weight

94,914 Da

OMIM

610166

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IQSEC1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IQSEC1. It may not necessarily be applicable to this product.

NCBI GI #

16307438

NCBI GeneID

9922

NCBI Accession #

BC010267

UniProt Secondary Accession #

O94863; Q96D85

UniProt Related Accession #

Q6DN90

NCBI Official Full Name

Homo sapiens IQ motif and Sec7 domain 1, mRNA

NCBI Official Synonym Full Names

IQ motif and Sec7 domain 1

NCBI Official Symbol

IQSEC1

NCBI Official Synonym Symbols

BRAG2; GEP100; ARFGEP100; ARF-GEP100

UniProt Protein Name

IQ motif and SEC7 domain-containing protein 1

UniProt Synonym Protein Names

ADP-ribosylation factors guanine nucleotide-exchange protein 100; ADP-ribosylation factors guanine nucleotide-exchange protein 2; Brefeldin-resistant Arf-GEF 2 protein

Protein Family

IQ motif and SEC7 domain-containing protein

UniProt Gene Name

IQSEC1

UniProt Synonym Gene Names

ARFGEP100; BRAG2; KIAA0763; BRAG2

UniProt Entry Name

IQEC1_HUMAN

NCBI Protein Information

IQ motif and SEC7 domain-containing protein 1

UniProt Comments for IQSEC1

IQSEC1: In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin. Belongs to the BRAG family. Interacts with ARF6. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, ARF; Motility/polarity/chemotaxis; GAPs

Chromosomal Location of Human Ortholog: 3p25.2

Cellular Component: membrane

Biological Process: actin cytoskeleton organization and biogenesis

Research Articles on IQSEC1

1. Brag2 is essential for developmental and pathological angiogenesis by promoting endothelial cell sprouting through regulation of adhesion by beta1-integrin internalization and link for the first time the process of beta1-integrin endocytosis with angiogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IQSEC1 cdna clone

Products by Pathway	Pathway Diagram
Arf6 Signaling Events Pathway antibodies	Arf6 Signaling Events Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram

Diseases associated with IQSEC1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9 publications with IQSEC1 and Neoplasms
Adenocarcinoma Antibodies	>3 publications with IQSEC1 and Adenocarcinoma
Lung Diseases Antibodies	>3 publications with IQSEC1 and Lung Diseases
Liver Neoplasms Antibodies	>2 publications with IQSEC1 and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with IQSEC1 and Liver Diseases
Brain Diseases Antibodies	>1 publications with IQSEC1 and Brain Diseases
Disease Models, Animal Antibodies	>1 publications with IQSEC1 and Disease Models, Animal
Necrosis Antibodies	>1 publications with IQSEC1 and Necrosis
Carcinoma, Hepatocellular Antibodies	>1 publications with IQSEC1 and Carcinoma, Hepatocellular

Organs/Tissues associated with IQSEC1 cdna clone

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>5 publications with IQSEC1 and Lung
Blood Antibodies	>4 publications with IQSEC1 and Blood
Brain Antibodies	>3 publications with IQSEC1 and Brain
Spleen Antibodies	>2 publications with IQSEC1 and Spleen
Heart Antibodies	>2 publications with IQSEC1 and Heart
Vascular Antibodies	>2 publications with IQSEC1 and Vascular
Muscle Antibodies	>1 publications with IQSEC1 and Muscle
Liver Antibodies	>1 publications with IQSEC1 and Liver
Kidney Antibodies	>1 publications with IQSEC1 and Kidney
Embryonic Tissue Antibodies	>1 publications with IQSEC1 and Embryonic Tissue