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KEL cDNA Clone – Group, Metallo-Endopeptidase (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277780

MBS1277780 is a cDNA clone targeting KEL. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KEL, cDNA Clone
Full Product Name
KEL cDNA Clone
Product Gene Name
KEL cdna clone
Sequence
atggaaggtg gggaccaaag tgaggaagag ccgagggaac gcagccaggc aggtggaatg ggaactctct ggagccaaga gagcactcca gaagagaggc tgcccgtgga agggagcagg ccatgggcag tggccaggcg ggtgctgaca gctatcctga ttttgggcct gctcctttgt ttttctgtgc ttttgttcta caacttccag aactgtggcc ctcgcccctg tgagacatct gtgtgtttgg atctccggga tcattacctg gcctctggga acacaagtgt ggccccctgc accgacttct tcagctttgc ctgtggaagg gccaaagaga ccaataattc ttttcaggag cttgccacaa agaacaaaaa ccgacttcgg agaatactgg aggtccagaa ttcctggcac ccaggctctg gggaggagaa agccttccag ttctacaact cctgcatgga tacacttgcc attgaagctg cagggactgg tcccctcaga caagttattg aggagcttgg aggctggcgc atctctggta aatggacttc cttaaacttt aaccgaacgc tgagacttct gatgagtcag tatggccatt tccctttctt cagagcctac ctaggacctc atcctgcctc tccacacaca ccagtcatcc agatagacca gccagagttt gatgttcccc tcaagcaaga tcaagaacag aagatctatg cccagatctt tcgggaatac ctgacttacc tgaatcagct gggaaccttg ctgggaggag acccaagcaa ggtgcaagaa cactcttcct tgtcaatctc catcacttca cggctgttcc agtttctgag gcccctggag cagcggcggg cacagggcaa gctcttccag atggtcacta tcgaccagct caaggaaatg gcccccgcca tcgactggtt gtcctgcttg caagcgacat tcacaccgat gtccctgagc ccttctcagt ccctcgtggt ccatgacgtg gaatatttga aaaacatgtc acaactggtg gaggagatgc tgctaaagca gagggacttt ctgcagagcc acatgatctt agggctggtg gtgacccttt ctccagccct ggacagtcaa ttccaggagg cacgcagaaa gctcagccag aaactgcggg aactgacaga gcaaccaccc atgcctgccc gcccacgatg gatgaagtgc gtggaggaga caggcacgtt cttcgagccc acgctggcgg ctttgtttgt tcgtgaggcc tttggcccga gcacccgaag tgctgccatg aaattattca ctgcgatccg ggatgccctc atcactcgcc tcagaaacct tccctggatg aatgaggaga cccagaacat ggcccaggac aaggttgctc aactgcaggt ggagatgggg gcttcagaat gggccctgaa gccagagctg gcccgacaag aatacaacga tatacagctt ggatcgagct tcctgcagtc tgtcctgagc tgtgtccggt ccctccgagc tagaattgtc cagagcttct tgcagcctca cccccaacac aggtggaagg tgtccccttg ggacgtcaat gcttactatt cggtatctga ccatgtggta gtctttccag ctggactcct ccaaccccca ttcttccacc ctggctatcc cagagccgtg aactttggcg ctgctggcag catcatggcc cacgagctgt tgcacatctt ctaccagctc ttactgcctg ggggctgcct cgcctgtgac aaccatgccc tccaggaagc tcacctgtgc ctgaagcgcc attatgctgc ctttccatta cctagcagaa cctccttcaa tgactccctc acattcttag agaatgctgc agacgttggg gggctagcca tcgcgctgca ggcatacagc aagaggctgt tacggcacca tggggagact gtcctgccca gcctggacct cagcccccag cagatcttct ttcgaagcta tgcccaggtg atgtgtagga agcccagccc ccaggactct cacgacactc acagccctcc acacctccga gtccacgggc ccctcagcag caccccagcc tttgccaggt atttccgctg tgcacgtggt gctctcttga acccctccag ccgctgccag ctctggtaa
Molecular Weight
82,824 Da
OMIM
110900
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KEL cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KEL. It may not necessarily be applicable to this product.

NCBI GI #
13111928
NCBI GeneID
3792
NCBI Accession #
BC003135
UniProt Secondary Accession #
Q96RS8; Q99885; B2RBV4
UniProt Related Accession #
P23276
NCBI Official Full Name
Homo sapiens Kell blood group, metallo-endopeptidase, mRNA
NCBI Official Synonym Full Names
Kell blood group, metallo-endopeptidase
NCBI Official Symbol
KEL
NCBI Official Synonym Symbols
ECE3; CD238
UniProt Protein Name
Kell blood group glycoprotein
UniProt Synonym Protein Names
CD_antigen: CD238
Protein Family
Kell blood group glycoprotein
UniProt Gene Name
KEL
UniProt Entry Name
KELL_HUMAN
NCBI Protein Information
kell blood group glycoprotein

NCBI Summary for KEL

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
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UniProt Comments for KEL

KEL: Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. Belongs to the peptidase M13 family.

Protein type: EC 3.4.24.-; Protease; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: integral to membrane; plasma membrane

Molecular Function: metalloendopeptidase activity; protein binding

Biological Process: vasoconstriction

Disease: Blood Group--kell System
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Research Articles on KEL

1. The expression of Kell glycoprotein on RBCs is not critical to the erythrocyte function

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with KEL cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >23 publications with KEL and Neoplasms
 Nervous System Diseases Antibodies  >20 publications with KEL and Nervous System Diseases
 Drug Toxicity Antibodies  >18 publications with KEL and Drug Toxicity
 Liver Diseases Antibodies  >15 publications with KEL and Liver Diseases
 Cardiovascular Diseases Antibodies  >15 publications with KEL and Cardiovascular Diseases
 Anemia Antibodies  >12 publications with KEL and Anemia
 Disease Models, Animal Antibodies  >9 publications with KEL and Disease Models, Animal
 Inflammation Antibodies  >8 publications with KEL and Inflammation
 Hypertension Antibodies  >7 publications with KEL and Hypertension
 Poisoning Antibodies  >6 publications with KEL and Poisoning

Organs/Tissues associated with KEL cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with KEL and Brain
 Lung Antibodies  >13 publications with KEL and Lung
 Skin Antibodies  >13 publications with KEL and Skin
 Spleen Antibodies  >10 publications with KEL and Spleen
 Bone Marrow Antibodies  >7 publications with KEL and Bone Marrow
 Ovary Antibodies  >6 publications with KEL and Ovary
 Testis Antibodies  >5 publications with KEL and Testis
 Embryonic Tissue Antibodies  >4 publications with KEL and Embryonic Tissue
 Placenta Antibodies  >1 publications with KEL and Placenta
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