Human LAMP2 cDNA Clone Expression Plasmid – Cat# MBS1275848

LAMP2 cDNA Clone – Lysosomal-Associated Membrane Protein 2 (Human)

Name: LAMP2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275848
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275848

MBS1275848 is a cDNA clone targeting LAMP2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LAMP2, cDNA Clone

Full Product Name

LAMP2 cDNA Clone

Product Gene Name

LAMP2 cdna clone

Sequence

atggtgtgct tccgcctctt cccggttccg ggctcagggc tcgttctggt ctgcctagtc ctgggagctg tgcggtctta tgcattggaa cttaatttga cagattcaga aaatgccact tgcctttatg caaaatggca gatgaatttc acagttcgct atgaaactac aaataaaact tataaaactg taaccatttc agaccatggc actgtgacat ataatggaag catttgtggg gatgatcaga atggtcccaa aatagcagtg cagttcggac ctggcttttc ctggattgcg aattttacca aggcagcatc tacttattca attgacagcg tctcattttc ctacaacact ggtgataaca caacatttcc tgatgctgaa gataaaggaa ttcttactgt tgatgaactt ttggccatca gaattccatt gaatgacctt tttagatgca atagtttatc aactttggaa aagaatgatg ttgtccaaca ctactgggat gttcttgtac aagcttttgt ccaaaatggc acagtgagca caaatgagtt cctgtgtgat aaagacaaaa cttcaacagt ggcacccacc atacacacca ctgtgccatc tcctactaca acacctactc caaaggaaaa accagaagct ggaacctatt cagttaataa tggcaatgat acttgtctgc tggctaccat ggggctgcag ctgaacatca ctcaggataa ggttgcttca gttattaaca tcaaccccaa tacaactcac tccacaggca gctgccgttc tcacactgct ctacttagac tcaatagcag caccattaag tatctagact ttgtctttgc tgtgaaaaat gaaaaccgat tttatctgaa ggaagtgaac atcagcatgt atttggttaa tggctccgtt ttcagcattg caaataacaa tctcagctac tgggatgccc ccctgggaag ttcttatatg tgcaacaaag agcagactgt ttcagtgtct ggagcatttc agataaatac ctttgatcta agggttcagc ctttcaatgt gacacaagga aagtattcta cagcccaaga gtgttcgctg gatgatgaca ccattctaat cccaattata gttggtgctg gtctttcagg cttgattatc gttatagtga ttgcttacgt aattggcaga agaaaaagtt atgctggata tcagactctg taa

Molecular Weight

45,170 Da

OMIM

300257

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LAMP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMP2. It may not necessarily be applicable to this product.

NCBI GI #

12804214

NCBI GeneID

3920

NCBI Accession #

BC002965

UniProt Secondary Accession #

Q16641; Q6Q3G8; Q96J30; Q99534; Q9UD93; A8K4X5; D3DTF0

UniProt Related Accession #

P13473

NCBI Official Full Name

Homo sapiens lysosomal-associated membrane protein 2, mRNA

NCBI Official Synonym Full Names

lysosomal associated membrane protein 2

NCBI Official Symbol

LAMP2

NCBI Official Synonym Symbols

LAMPB; CD107b; LAMP-2; LGP110

UniProt Protein Name

Lysosome-associated membrane glycoprotein 2

UniProt Synonym Protein Names

CD107 antigen-like family member B; CD_antigen: CD107b

Protein Family

Lysosome-associated membrane glycoprotein

UniProt Gene Name

LAMP2

UniProt Synonym Gene Names

LAMP-2; Lysosome-associated membrane protein 2

UniProt Entry Name

LAMP2_HUMAN

NCBI Protein Information

lysosome-associated membrane glycoprotein 2

NCBI Summary for LAMP2

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]

UniProt Comments for LAMP2

LAMP2: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Defects in LAMP2 are the cause of Danon disease (DAND); also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes. Belongs to the LAMP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: extracellular space; late endosome; late endosome membrane; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: enzyme binding; protein binding

Biological Process: platelet degranulation; protein import; protein stabilization; regulation of protein stability

Disease: Danon Disease

Research Articles on LAMP2

1. LAMP-2C serves as a natural inhibitor of chaperone-mediated autophagy that can selectively skew MHCII presentation of cytoplasmic antigens

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LAMP2 cdna clone

Products by Pathway	Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
Senescence And Autophagy Pathway antibodies	Senescence And Autophagy Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram

Diseases associated with LAMP2 cdna clone

Disease Name	Pubmed Publications
Cardiomyopathies Antibodies	>54 publications with LAMP2 and Cardiomyopathies
Glycogen Storage Disease Type IIb Antibodies	>41 publications with LAMP2 and Glycogen Storage Disease Type IIb
Hypertrophy Antibodies	>21 publications with LAMP2 and Hypertrophy
Neoplasms Antibodies	>20 publications with LAMP2 and Neoplasms
Kidney Diseases Antibodies	>8 publications with LAMP2 and Kidney Diseases
Inflammation Antibodies	>8 publications with LAMP2 and Inflammation
Drug Toxicity Antibodies	>7 publications with LAMP2 and Drug Toxicity
Liver Diseases Antibodies	>6 publications with LAMP2 and Liver Diseases
Congenital Abnormalities Antibodies	>6 publications with LAMP2 and Congenital Abnormalities
Fibrosis Antibodies	>4 publications with LAMP2 and Fibrosis

Organs/Tissues associated with LAMP2 cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>50 publications with LAMP2 and Muscle
Blood Antibodies	>39 publications with LAMP2 and Blood
Heart Antibodies	>38 publications with LAMP2 and Heart
Brain Antibodies	>25 publications with LAMP2 and Brain
Liver Antibodies	>21 publications with LAMP2 and Liver
Nerve Antibodies	>17 publications with LAMP2 and Nerve
Vascular Antibodies	>11 publications with LAMP2 and Vascular
Kidney Antibodies	>10 publications with LAMP2 and Kidney
Skin Antibodies	>9 publications with LAMP2 and Skin
Lung Antibodies	>8 publications with LAMP2 and Lung