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LARS2 cDNA Clone – Leucyl-Trna Synthetase 2, Mitochondrial (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278503

MBS1278503 is a cDNA clone targeting LARS2. More details

$630 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LARS2, cDNA Clone
Full Product Name
LARS2 cDNA Clone
Product Gene Name
LARS2 cdna clone
Sequence
atggcttctg tttggcagag attgggtttt tatgcctctc ttctgaaaag acagctaaat ggtgggccag atgtcatcaa gtgggaaagg agagtaattc ccggatgtac cagaagcatc tacagtgcca cgggaaagtg gacaaaagag tatacattgc agacaagaaa ggatgttgag aaatggtggc atcaacgaat aaaagaacag gcctccaaaa tttcagaagc tgataaatcg aagccaaaat tttacgtgct ttccatgttc ccttatcctt ctggtaagct gcacatgggc catgtgcgtg tctacaccat cagcgacacc atagcacggt tccagaagat gagagggatg caggtcatca accccatggg atgggatgct tttggattgc ctgctgaaaa tgccgcagtc gagaggaatc tacatccaca aagttggaca caaagtaata ttaaacacat gaggaaacag cttgatcgtc tgggcctgtg tttcagctgg gatagggaaa taactacgtg tttgccagat tactacaagt ggactcagta tctctttatt aaactgtatg aggctgggct ggcctatcaa aaggaggccc tggttaactg ggacccagtg gatcaaacag tgcttgccaa tgagcaggtg gatgaacatg gctgttcatg gcgttctgga gcaaaggtgg aacagaagta cctcagacaa tggtttatta agacaaccgc ttatgcaaag gccatgcagg acgcgttggc agaccttcca gaatggtatg gaataaaagg catgcaagcc cactggattg gggactgtgt gggctgccac ctggacttca cattaaaggt tcatgggcaa gccacgggcg aaaagctgac tgcctatacg gccacccctg aagccattta tggcacctcc cacgtggcca tctcgcccag ccacagactc ctacatgggc acagctctct gaaggaagcc ttgaggatgg cccttgtccc tggcaaagat tgcctcacgc ctgtaatggc tgtgaacatg ctcacccagc aggaggtccc tgtcgttatt ttggccaaag ctgacttgga aggctctctg gattcaaaaa taggaattcc cagtactagc tcagaggaca ccatcttagc ccaaaccctg ggcctggcct actctgaagt cattgaaact ttgccagatg gcacagagag actgagcagc tctgctgagt tcacaggtat gacccggcag gatgcttttc tagccctgac tcagaaagcc cgggggaaga gagtgggtgg agacgtgaca agtgataaac tgaaagactg gctgatttca cggcagcggt actggggcac accaatcccc attgtccact gcccagtctg tggccccaca cctgtgcccc tggaggactt gcctgtgacc ctgcccaaca tcgcatcttt cactggcaag ggaggccccc cactggccat ggcttcagag tgggtgaact gctcctgccc aaggtgcaag ggagcagcca agagagagac agacacgatg gatacctttg ttgattctgc ttggtactac ttcagataca ctgaccctca taatccacac agccctttta acacagcagt ggccgattac tggatgcctg tggatttgta cattggaggg aaagaacatg ccgtcatgca cttgttctat gcaagattct ttagtcattt ttgccatgat caaaaaatgg ttaaacatag ggagcctttt cataagctgc tggcccaagg ccttatcaag gggcagacat tccgcctacc atctggacag tatctacaga gagaggaagt ggatctcaca ggttccgttc ctgttcatgc aaaaacgaaa gagaagttag aggtgacgtg ggagaagatg agtaagtcca aacacaacgg ggtggaccca gaggaagttg tggagcagta tgggatcgac acgattcggc tctacatcct ttttgctgcc cctcctgaga aggatatctt gtgggatgtg aaaactgatg ctctccctgg ggtgctgaga tggcaacaac gactgtggac cttgacaact cggtttattg aggccagggc ttctgggaag tctccccagc ctcagctgct gagtaacaag gagaaagccg aggccaggaa gctctgggag tacaagaact ccgtcatctc tcaggtgacc acccatttca cagaggactt ctcactgaat tctgcaattt ctcagctgat gggactcagc aatgccctct cgcaagcctc tcagagcgtc attctccaca gccccgagtt tgaggatgct ttgtgtgccc tgatggtgat ggctgctcca ctggcccctc atgtaacctc agagatctgg gcaggcctgg cgctggtgcc gaggaagctc tgtgcccact acacttggga tgccagtgtg ctgctccagg catggcctgc tgtggacccg gagttcctgc agcagcctga ggttgtccag atggcagttc tgatcaacaa taaagcttgt ggcaaaattc ctgtgcccca acaagttgcc cgggaccagg acaaagtcca cgaatttgtt cttcaaagcg agctgggtgt caggcttttg caaggacgaa gcatcaagaa gtccttcctt tccccgagaa ctgccctcat caacttcctg gtgcaagatt ga
Molecular Weight
101,976 Da
OMIM
604544
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LARS2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LARS2. It may not necessarily be applicable to this product.

NCBI GI #
34190294
NCBI GeneID
23395
NCBI Accession #
BC025989
UniProt Related Accession #
Q15031
NCBI Official Full Name
Homo sapiens leucyl-tRNA synthetase 2, mitochondrial, mRNA
NCBI Official Synonym Full Names
leucyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
LARS2
NCBI Official Synonym Symbols
HLASA; LEURS; PRLTS4; mtLeuRS
UniProt Protein Name
Probable leucine--tRNA ligase, mitochondrial
UniProt Synonym Protein Names
Leucyl-tRNA synthetase; LeuRS
Protein Family
Probable leucine--tRNA ligase
UniProt Gene Name
LARS2
UniProt Synonym Gene Names
KIAA0028; LeuRS
UniProt Entry Name
SYLM_HUMAN
NCBI Protein Information
probable leucine--tRNA ligase, mitochondrial

NCBI Summary for LARS2

This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

UniProt Comments for LARS2

LARS2: a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.4; Ligase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cytosol; mitochondrial matrix; mitochondrion

Molecular Function: leucine-tRNA ligase activity

Biological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Disease: Hydrops, Lactic Acidosis, And Sideroblastic Anemia; Perrault Syndrome 4
Show more

Research Articles on LARS2

1. analysis of the CP1 domain in human mitochondrial leucyl-tRNA synthetase

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LARS2 cdna clone

 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Mitochondrial TRNA Aminoacylation Pathway antibodies  Mitochondrial TRNA Aminoacylation Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram

Diseases associated with LARS2 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with LARS2 and Neoplasms
 Nervous System Diseases Antibodies  >2 publications with LARS2 and Nervous System Diseases
 Gonadal Disorders Antibodies  >1 publications with LARS2 and Gonadal Disorders
 Congenital Abnormalities Antibodies  >1 publications with LARS2 and Congenital Abnormalities

Organs/Tissues associated with LARS2 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with LARS2 and Liver
 Brain Antibodies  >1 publications with LARS2 and Brain
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