Human LAX1 cDNA Clone Expression Plasmid – Cat# MBS1267283

LAX1 cDNA Clone – Lymphocyte Transmembrane Adaptor 1 (Human)

Name: LAX1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267283
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267283

MBS1267283 is a cDNA clone targeting LAX1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LAX1, cDNA Clone

Full Product Name

LAX1 cDNA Clone

Product Gene Name

LAX1 cdna clone

Sequence

atgcccttgc tgactttgcc acaaaccaga caaagagcca aaaatattta tgacatcttg ccttggcgac aggaagacct ggggagacat gagtcgagga gtatgcgcat tttcagtact gagagcctcc tctccagaaa ttctgagagc ccggagcatg tgccctccca agcaggcaat gccttccagg agcatacagc ccacatccat gccacagagt acgcggtggg tatctatgac aacgccatgg tcccccagat gtgtgggaac ctcactccct cggcacactg catcaatgtc agagcttcca gagactgcgc aagcatttct tcagaggatt cgcatgatta tgtcaatgtc cccacagcag aagagattgc tgagactcta gcttctacca aaagcccttc cagaaatctc tttgttcttc ccagtaccca gaagctggag tttactgagg aaagagatga gggctgtgga gatgctggtg actgcaccag tttgtattct ccaggagctg aggacagtga ttcactcagc aatggagaag gttcttctca gatctcaaat gactatgtca acatgacagg gttggatctc agtgccatcc aggaaaggca gctctgggtg gcttttcagt gctgcagaga ctatgaaaat gttccagcag cagatcccag tggaagccag cagcaggctg agaaagatgt gccatcctca aacataggtc atgtcgagga caagacagat gatcccggga cccatgtcca atgtgtcaaa aggacattcc ttgcttcagg ggattatgca gactttcagc cattcacaca gagtgaggac agtcagatga aacatagaga agagatgtca aatgaggact ccagtgacta tgaaaatgtg ctaactgcca agttaggagg cagggactct gagcaggggc ctggcactca gctccttcct gatgaatga

Molecular Weight

42,491 Da

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LAX1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAX1. It may not necessarily be applicable to this product.

NCBI GI #

46854880

NCBI GeneID

54900

NCBI Accession #

BC069650

UniProt Secondary Accession #

Q6NSZ6; Q9NXB4; B7Z744; J3KP69

UniProt Related Accession #

Q8IWV1

NCBI Official Full Name

Homo sapiens lymphocyte transmembrane adaptor 1, mRNA

NCBI Official Synonym Full Names

lymphocyte transmembrane adaptor 1

NCBI Official Symbol

LAX1

NCBI Official Synonym Symbols

LAX

UniProt Protein Name

Lymphocyte transmembrane adapter 1

UniProt Synonym Protein Names

Linker for activation of X cells; Membrane-associated adapter protein LAX

Protein Family

Lymphocyte transmembrane adapter

UniProt Gene Name

LAX1

UniProt Synonym Gene Names

LAX

UniProt Entry Name

LAX1_HUMAN

NCBI Protein Information

lymphocyte transmembrane adapter 1

UniProt Comments for LAX1

LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; lipid raft; membrane; plasma membrane

Molecular Function: protein binding; protein kinase binding; SH2 domain binding

Biological Process: B cell activation; immune response; inactivation of MAPK activity; negative regulation of T cell activation

Research Articles on LAX1

1. TRIM required LAX for binding to Rab8 in a complex, a novel CTLA-4/TRIM/LAX/Rab8 effector complex in the transport of CTLA-4 to the surfaces of T cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with LAX1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with LAX1 and Neoplasms

Organs/Tissues associated with LAX1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>8 publications with LAX1 and Blood