Human LBP cDNA Clone Expression Plasmid – Cat# MBS1266903

LBP cDNA Clone – Lipopolysaccharide Binding Protein (Human)

Name: LBP cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266903
Price: 570 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266903

MBS1266903 is a cDNA clone targeting LBP. More details

$570 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LBP, cDNA Clone

Full Product Name

LBP cDNA Clone

Product Gene Name

LBP cdna clone

Sequence

atgggggcct tggccagagc cctgccgtcc atactgctgg cattgctgct tacgtccacc ccagaggctc tgggtgccaa ccccggcttg gtcgccagga tcaccgacaa gggactgcag tatgcggccc aggaggggct attggctctg cagagtgagc tgctcaggat cacgctgcct gacttcaccg gggacttgag gatcccccac gtcggccgtg ggcgctatga gttccacagc ctgaacatcc acagctgtga gctgcttcac tctgcgctga ggcctgtccc tggccagggc ctgagtctca gcatctccga ctcctccatc cgggtccagg gcaggtggaa ggtgcgcaag tcattcttca aactacaggg ctcctttgat gtcagtgtca agggcatcag catttcggtc aacctcctgt tgggcagcga gtcctccggg aggcccacag ttactgcctc cagctgcagc agtgacatcg ctgacgtgga ggtggacatg tcgggagact tggggtggct gttgaacctc ttccacaacc agattgagtc caagttccag aaagtactgg agagcaggat ttgcgaaatg atccagaaat cggtgtcctc cgatctacag ccttatctcc aaactctgcc agttacaaca gagattgaca gtttcgccga cattgattat agcttagtgg aagcccctcg ggcaacagcc cagatgctgg aggtgatgtt taagggtgaa atctttcatc gtaaccaccg ttctccagtt accctccttg ctgcagtcat gagccttcct gaggaacaca acaaaatggt ctactttgcc atctcggatt atgtcttcaa cacggccagc ctggtttatc atgaggaagg atatctgaac ttctccatca cagatgacat gataccgcct gactctaata tccgactgac caccaagtcc ttccgaccct tcgtcccacg gttagccagg ctctacccca acatgaacct ggaactccag ggatcagtgc cctctgctcc gctcctgaac ttcagccctg ggaatctgtc tgtggacccc tatatggaga tagatgcctt tgtgctcctg cccagctcca gcaaggagcc tgtcttccgg ctcagtgtgg ccactaatgt gtccgccacc ttgaccttca ataccagcaa gatcactggg ttcctgaagc caggaaaggt aaaagtggaa ctgaaagaat ccaaagttgg actattcaat gcagagctgt tggaagcgct cctcaactat tacatcctta acaccttcta ccccaagttc aatgataagt tggccgaagg cttccccctt cctctgctga agcgtgttca gctctacgac cttgggctgc agatccataa ggacttcccc tccaggaggg accaccctcc ctga

Molecular Weight

53,384 Da

OMIM

151990

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LBP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LBP. It may not necessarily be applicable to this product.

NCBI GI #

18490597

NCBI GeneID

3929

NCBI Accession #

BC022256

UniProt Secondary Accession #

O43438; Q92672; Q9H403; Q9UD66; B2R938

UniProt Related Accession #

P18428

NCBI Official Full Name

Homo sapiens lipopolysaccharide binding protein, mRNA

NCBI Official Synonym Full Names

lipopolysaccharide binding protein

NCBI Official Symbol

LBP

NCBI Official Synonym Symbols

BPIFD2

UniProt Protein Name

Lipopolysaccharide-binding protein

Protein Family

Lipopolysaccharide-binding protein

UniProt Gene Name

LBP

UniProt Synonym Gene Names

LBP

UniProt Entry Name

LBP_HUMAN

NCBI Protein Information

lipopolysaccharide-binding protein

NCBI Summary for LBP

The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]

UniProt Comments for LBP

LBP: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: cell surface; extracellular region; extracellular space

Molecular Function: lipopolysaccharide binding; protein binding; receptor binding

Biological Process: acute-phase response; cellular defense response; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; detection of molecule of bacterial origin; innate immune response; lipopolysaccharide transport; lipopolysaccharide-mediated signaling pathway; macrophage activation during immune response; negative regulation of tumor necrosis factor production; opsonization; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of macrophage activation; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor production; response to lipopolysaccharide; toll-like receptor 4 signaling pathway

Research Articles on LBP

1. The main findings of this study are that, in acute stroke patients, levels of LBP, IL-10, IL-6 and CRP show a different time course in patients with and without post-stroke infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LBP cdna clone

Products by Pathway	Pathway Diagram
IL6-mediated Signaling Events Pathway antibodies	IL6-mediated Signaling Events Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
NF-kappa B Signaling Pathway antibodies	NF-kappa B Signaling Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies	Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram
Toll-Like Receptors Cascades Pathway antibodies	Toll-Like Receptors Cascades Pathway Diagram
Toll-like Receptor Signaling Pathway antibodies	Toll-like Receptor Signaling Pathway Diagram
Toll-like Receptor Signaling Pathway antibodies	Toll-like Receptor Signaling Pathway Diagram

Diseases associated with LBP cdna clone

Disease Name	Pubmed Publications
Pain Antibodies	>2528 publications with LBP and Pain
Inflammation Antibodies	>294 publications with LBP and Inflammation
Necrosis Antibodies	>224 publications with LBP and Necrosis
Sepsis Antibodies	>160 publications with LBP and Sepsis
Liver Diseases Antibodies	>66 publications with LBP and Liver Diseases
Obesity Antibodies	>50 publications with LBP and Obesity
Drug Toxicity Antibodies	>46 publications with LBP and Drug Toxicity
Brain Diseases Antibodies	>38 publications with LBP and Brain Diseases
Hypertension Antibodies	>36 publications with LBP and Hypertension
Heart Diseases Antibodies	>22 publications with LBP and Heart Diseases

Organs/Tissues associated with LBP cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>628 publications with LBP and Blood
Muscle Antibodies	>499 publications with LBP and Muscle
Liver Antibodies	>149 publications with LBP and Liver
Brain Antibodies	>81 publications with LBP and Brain
Heart Antibodies	>54 publications with LBP and Heart
Connective Tissue Antibodies	>27 publications with LBP and Connective Tissue
Prostate Antibodies	>8 publications with LBP and Prostate
Salivary Gland Antibodies	>7 publications with LBP and Salivary Gland
Pancreas Antibodies	>3 publications with LBP and Pancreas