Human LETM1 cDNA Clone Expression Plasmid – Cat# MBS1269484

LETM1 cDNA Clone – Leucine Zipper-Ef-Hand Containing Transmembrane Protein 1 (Human)

Name: LETM1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269484
Price: 835 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269484

MBS1269484 is a cDNA clone targeting LETM1. More details

$835 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LETM1, cDNA Clone

Full Product Name

LETM1 cDNA Clone

Product Gene Name

LETM1 cdna clone

Sequence

atggcgtcca tcttactgag gagctgccgc ggccgggcgc ccgcccgcct cccgccgccg cctcggtaca ccgtcccgcg gggtagtcca ggggatcctg ctcatctcag ctgtgccagc accctggggt tgaggaactg cctgaatgtt ccatttggct gctgcactcc catccaccct gtgtacacat cctccagagg cgatcacctc ggctgttggg ctctgaggcc cgagtgcctt cgcatagtgt cgagagcgcc atggacctct acctctgtgg gttttgtggc tgtgggacct cagtgccttc ctgtgcgtgg ctggcactct tcgcgccctg ttcgcgatga ctcggtagta gagaagtccc tcaagtcctt gaaggacaag aacaagaagc tggaggaagg cggcccggtg tacagccccc ccgcagaggt ggtggtgaag aagtccctgg ggcagcgggt gctggacgag ctgaagcact actaccatgg cttccgcctg ctatggatcg acaccaagat cgcggcacgc atgctctggc gcatcctcaa cggccacagc ctgacccgcc gggagcgcag gcagtttctc cggatctgcg ctgacctctt ccgcctggtg ccgttccttg tgttcgtggt ggtgccgttc atggagtttc tgctgcctgt tgctgtgaag ctcttcccca acatgttgcc atccacattt gagactcagt cactcaagga ggagaggctg aagaaggagc ttcgggtcaa gctggagctg gccaagttcc tccaggacac catcgaggag atggccttga agaacaaggc agccaagggc agcgccacca aagacttctc tgtgtttttc cagaagatcc gggaaacagg ggagaggccc agcaatgagg aaatcatgcg tttttccaaa ttatttgagg atgagctgac cctggacaac ctgacacggc cgcagctggt ggccctgtgc aagctgctgg agctacagtc catcggcacc aacaacttcc tgcgcttcca gcttaccatg cggctgcgct ccataaaggc agacgacaag ctgattgctg aggaaggggt ggacagcctg aatgtcaagg agctgcaggc agcgtgtcgg gcacgaggca tgcgggccct gggcgtcacg gaagaccgcc tgaggggtca gctgaagcag tggctggacc tgcacctgca tcaggagatc cccacatcgc tgctcatcct gtcccgggcc atgtacctcc cggacaccct ctctccagcc gaccagctca agtccacact gcagaccctc ccagagattg tggcaaagga agcacaggtg aaagtggccg aggtggaggg cgagcaggtg gacaacaagg ccaagctgga ggccacgctg caggaggagg cggccatcca gcaggagcac cgtgagaagg agctgcagaa gcgctcggag gtggcgaagg attttgagcc cgaacgtgtg gtagctgctc cccaaaggcc ggggaccgag ccacagccag aaatgcctga cacagtcctg cagtcagaga ccttgaagga cactgccccg gtgctggagg gcttgaagga ggaagagatc acgaaggagg aaatcgacat cctcagcgat gcctgctcta agctgcagga gcagaagaag tcactcacca aggagaagga ggagctggag ctgctgaagg aggatgtgca ggactacagc gaggacttgc aggagatcaa gaaggaactt tcaaagactg gtgaagaaaa atacgtggaa gaatctaaag ccagcaagag attgacaaaa agggtgcagc aaatgatcgg gcagatcgat ggcttgatct cgcagctgga gatggaccag caggctggca agctggcccc ggccaacggc atgcccacgg gggagaacgt catcagtgtc gctgagctca tcaacgccat gaagcaagtc aagcacattc ccgaaagcaa gctcaccagc ctggccgcag cactggatga aaacaaggat ggcaaggtca acatcgacga cctcgtcaag gtgattgagc tggtggacaa agaagatgtt cacatctcca ccagccaggt ggctgagatt gtagcaacac tggaaaaaga ggagaaggtg gaggagaagg agaaggccaa agagaaggca gagaaggagg tcgcagaggt gaagagctag

Molecular Weight

33,245 Da

OMIM

604407

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LETM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LETM1. It may not necessarily be applicable to this product.

NCBI GI #

15680274

NCBI GeneID

3954

NCBI Accession #

BC014500

UniProt Secondary Accession #

Q9UF65; B4DED2

UniProt Related Accession #

O95202

NCBI Official Full Name

Homo sapiens leucine zipper-EF-hand containing transmembrane protein 1, mRNA

NCBI Official Synonym Full Names

leucine zipper and EF-hand containing transmembrane protein 1

NCBI Official Symbol

LETM1

UniProt Protein Name

LETM1 and EF-hand domain-containing protein 1, mitochondrial

UniProt Synonym Protein Names

Leucine zipper-EF-hand-containing transmembrane protein 1

Protein Family

LETM1 and EF-hand domain-containing protein

UniProt Gene Name

LETM1

UniProt Entry Name

LETM1_HUMAN

NCBI Protein Information

LETM1 and EF-hand domain-containing protein 1, mitochondrial

NCBI Summary for LETM1

This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009]

UniProt Comments for LETM1

LETM1: Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Calcium-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: mitochondrial inner membrane; mitochondrion

Molecular Function: protein binding

Biological Process: cristae formation

Disease: Wolf-hirschhorn Syndrome

Research Articles on LETM1

1. LETM1 protein overexpression is associated with Triple negative breast cancer progression, and may be a potential biomarker for poor prognostic evaluation of Triple negative breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with LETM1 cdna clone

Disease Name	Pubmed Publications
Wolf-Hirschhorn Syndrome Antibodies	>21 publications with LETM1 and Wolf-Hirschhorn Syndrome
Seizures Antibodies	>11 publications with LETM1 and Seizures
Craniofacial Abnormalities Antibodies	>4 publications with LETM1 and Craniofacial Abnormalities
Intellectual Disability Antibodies	>3 publications with LETM1 and Intellectual Disability
Eye Diseases Antibodies	>3 publications with LETM1 and Eye Diseases
Atrophy Antibodies	>2 publications with LETM1 and Atrophy
Necrosis Antibodies	>2 publications with LETM1 and Necrosis
Kidney Diseases Antibodies	>2 publications with LETM1 and Kidney Diseases
Carcinoma, Hepatocellular Antibodies	>2 publications with LETM1 and Carcinoma, Hepatocellular
Neoplasms Antibodies	>2 publications with LETM1 and Neoplasms

Organs/Tissues associated with LETM1 cdna clone

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>3 publications with LETM1 and Heart
Muscle Antibodies	>1 publications with LETM1 and Muscle
Pancreas Antibodies	>1 publications with LETM1 and Pancreas
Testis Antibodies	>1 publications with LETM1 and Testis
Lung Antibodies	>1 publications with LETM1 and Lung
Eye Antibodies	>1 publications with LETM1 and Eye
Brain Antibodies	>1 publications with LETM1 and Brain