Human MAP4 cDNA Clone Expression Plasmid – Cat# MBS1267212

MAP4 cDNA Clone – Microtubule-Associated Protein 4 (Human)

Name: MAP4 cDNA Clone; Microtubule-Associated Protein 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267212
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267212

MBS1267212 is a cDNA clone targeting MAP4. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MAP4, cDNA Clone

Full Product Name

MAP4 cDNA Clone

Product Gene Name

MAP4 cdna clone

Sequence

atggctgacc tcagtcttgc agatgcatta acagaaccat ctccagacat tgagggagag ataaagcggg acttcattgc cacactagag gcagaggcct ttgatgatgt tgtgggagaa actgttggaa aaacagacta tattcctctc ctggatgttg atgagaaaac cgggaactca gagtcaaaga agaaaccgtg ctcagaaact agccagattg aagatactcc atcttctaaa ccaacactcc tagccaatgg tggtcatgga gtagaaggga gcgatactac agggtctcca actgaattcc ttgaagagaa aatggcctac caggaatacc caaatagcca gaactggcca gaagatacca acttttgttt ccaacctgag caagtggtcg atcctatcca gactgatccc tttaagatgt accatgatga tgacctggca gatttggtct ttccctccag tgcgacagct gatacttcaa tatttgcagg acaaaatgat cccttgaaag acagttacgg tatgtctccc tgcaacacag ctgttgtacc tcaggggtgg tctgtggaag ccttaaactc tccacactca gagtcctttg tttccccaga ggctgttgca gaacctcctc agccaacggc agttccctta gagctagcca aggagataga aatggcatca gaagagaggc caccagcaca agcattggaa ataatgatgg gactgaagac tactgacatg gcaccatcta aagaaacaga gatggccctc gccaaggaca tggcactagc tacaaaaacc gaggtggcat tggctaaaga tatggaatca cccaccaaat tagatgtgac actggccaag gacatgcagc catccatgga atcagatatg gccctagtca aggacatgga actacccaca gaaaaagaag tggccctggt taaggatgtc agatggccca cagaaacaga tgtatcttca gccaagaatg tggtactgcc cacagaaaca gaggtagccc cagccaagga tgtgacactg ttgaaagaaa cagagagggc atctcctata aaaatggact tagccccttc caaggacatg ggaccaccca aagaaaacaa gaaagaaaca gagagggcat ctcctataaa aatggacttg gctccttcca aggacatggg accacccaaa gaaaacaaga tagtcccagc caaggatttg gtattactct cagaaataga ggtggcacag gctaatgaca ttatatcatc cacagaaata tcctctgctg agaaggtggc tttgtcctca gaaacagagg tagccctggc cagggacatg acactgcccc cggaaaccaa cgtgatcttg accaaggata aagcactacc tttagaagca gaggtggccc cagtcaagga catggctcaa ctcccagaaa cagaaatagc cccggccaag gatgtggctc cgtccacagt aaaagaagtg ggcttgttga aggacatgtc tccactatca gaaacagaaa tggctctggg caaggatgtg actccacctc cagaaacaga agtagttctc atcaagaacg tatgtctgcc tccagaaatg gaggtggccc tgactgagga tcaggtccca gccctcaaaa cagaagctcc caccaccatt ggtgggttga ataaaaaacc catgagcctt gcttcaggct tagtgccagc tgccccaccc aaacgccctg ccgtcgcctc tgccaggcct tccatcttac cttcaaaaga cgtgaagcca aagcccattg cagatgcaaa ggctcctgag aagcgggcct caccatccaa gccagcttct gccccagcct ccagatctgg gtccaagagc actcagactg ttgcaaaaac cacaacagct gctgctgttg cctcaactgg cccaagcagt aggagcccct ccacgctcct gcccaagaag cccactgcca ttaagactga gggaaaacct gcagaagtca agaagatgac tgcaaagtct gtaccagctg acttgagtcg cccaaagagc acctccacca gttccatgaa gaaaaccacc actctcagtg ggacagcccc cgctgcaggg gtggttccca gccgagtcaa ggccacaccc atgccctccc ggccctccac aactcctttc atagacaaga agcccacctc ggccaaaccc agctccacca ccccccggct cagccgcctg gccaccaata cttctgctcc tgatctgaag aatgtccgct ccaaggttgg ctccacggaa aacatcaagc atcagcctgg aggaggccgg gccaaagtag agaaaaaaac agaggcagct gctacaaccc gaaagcctga atctaatgca gtcactaaaa cagccggccc aattgcaagt gcacagaaac aacctgcggg gaaagtccag atagtctcca aaaaagtgag ctacagccat attcagtcca agtgtggttc caaggacaat attaagcatg tccctggagg tggtaatgtt cagattcaga acaagaaagt ggacatctct aaggtctcct ccaagtgtgg gtctaaggct aacatcaagc acaagcctgg tggaggagat gtcaagattg aaagtcagaa gttgaacttc aaggagaagg cccaggccaa ggtgggatcc ctcgataatg tgggccacct acctgcagga ggtgctgtga agactgaggg cggtggcagc gaggctcctc tgtgtccggg tccccctgct ggggaggagc cggccatctc tgaggcagcg cctgaagctg gcgcccccac ttcagccagt ggcctcaatg gccaccccac cctgtcaggg ggtggtgacc aaagggaggc ccagaccttg gacagccaga tccaggagac aagcatctaa

Molecular Weight

10,441 Da

OMIM

157132

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MAP4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MAP4. It may not necessarily be applicable to this product.

NCBI GI #

33870800

NCBI GeneID

4134

NCBI Accession #

BC008715

UniProt Secondary Accession #

Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9

UniProt Related Accession #

P27816

NCBI Official Full Name

Homo sapiens microtubule-associated protein 4, mRNA

NCBI Official Synonym Full Names

microtubule associated protein 4

NCBI Official Symbol

MAP4

UniProt Protein Name

Microtubule-associated protein 4

Protein Family

Microtubule-associated protein

UniProt Gene Name

MAP4

UniProt Synonym Gene Names

MAP-4

UniProt Entry Name

MAP4_HUMAN

NCBI Protein Information

microtubule-associated protein 4

NCBI Summary for MAP4

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

UniProt Comments for MAP4

MAP4: a microtuble-associated protein detected predominately in nonneuronal cells. May play a role in microtubule stabilization as well as promoting microtubule assembly. Four alternatively spliced variants have been described.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: axoneme; cytoplasm; microtubule associated complex; microtubule cytoskeleton; neuron projection; plasma membrane

Molecular Function: microtubule binding; protein binding; structural molecule activity

Biological Process: cell division; establishment of spindle orientation; microtubule sliding; mitotic spindle organization and biogenesis; neurite development

Research Articles on MAP4

1. We demonstrated that the MAP4 (Ser696 and Ser787) phosphorylation increased concomitantly with the p38/MAPK pathway activation by the LPS and TNF-alpha stimulation of HPMECs, which induced MT disassembly followed by hyperpermeability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with MAP4 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>23 publications with MAP4 and Neoplasms
Nervous System Diseases Antibodies	>19 publications with MAP4 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>14 publications with MAP4 and Cardiovascular Diseases
Heart Diseases Antibodies	>11 publications with MAP4 and Heart Diseases
Hypertrophy Antibodies	>11 publications with MAP4 and Hypertrophy
Breast Neoplasms Antibodies	>7 publications with MAP4 and Breast Neoplasms
Immune System Diseases Antibodies	>5 publications with MAP4 and Immune System Diseases
Heart Failure Antibodies	>5 publications with MAP4 and Heart Failure
Ovarian Neoplasms Antibodies	>4 publications with MAP4 and Ovarian Neoplasms
Drug Toxicity Antibodies	>3 publications with MAP4 and Drug Toxicity

Organs/Tissues associated with MAP4 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>65 publications with MAP4 and Brain
Muscle Antibodies	>22 publications with MAP4 and Muscle
Blood Antibodies	>21 publications with MAP4 and Blood
Heart Antibodies	>20 publications with MAP4 and Heart
Spinal Cord Antibodies	>13 publications with MAP4 and Spinal Cord
Kidney Antibodies	>12 publications with MAP4 and Kidney
Nerve Antibodies	>12 publications with MAP4 and Nerve
Liver Antibodies	>7 publications with MAP4 and Liver
Ovary Antibodies	>5 publications with MAP4 and Ovary
Vascular Antibodies	>4 publications with MAP4 and Vascular