Human MAPK9 cDNA Clone Expression Plasmid – Cat# MBS1274840

MAPK9 cDNA Clone – Mitogen-Activated Protein Kinase 9 (Human)

Name: MAPK9 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274840
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274840

MBS1274840 is a cDNA clone targeting MAPK9. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MAPK9, cDNA Clone

Full Product Name

MAPK9 cDNA Clone

Product Gene Name

MAPK9 cdna clone

Sequence

atgagcgaca gtaaatgtga cagtcagttt tatagtgtgc aagtggcaga ctcaaccttc actgtcctaa aacgttacca gcagctgaaa ccaattggct ctggggccca agggattgtt tgtgctgcat ttgatacagt tcttgggata aatgttgcag tcaagaaact aagccgtcct tttcagaacc aaactcatgc aaagagagct tatcgtgaac ttgtcctctt aaaatgtgtc aatcataaaa atataattag tttgttaaat gtgtttacac cacaaaaaac tctagaagaa tttcaagatg tgtatttggt tatggaatta atggatgcta acttatgtca ggttattcac atggagctgg atcatgaaag aatgtcctac cttctttacc agatgctttg tggtattaaa catctgcatt cagctggtat aattcataga gatttgaagc ctagcaacat tgttgtgaaa tcagactgca ccctgaagat ccttgacttt ggcctggccc ggacagcgtg cactaacttc atgatgaccc cttacgtggt gacacggtac taccgggcgc ccgaagtcat cctgggtatg ggctacaaag agaacgttga tatctggtca gtgggttgca tcatgggaga gctggtgaaa ggttgtgtga tattccaagg cactgaccat attgatcagt ggaataaagt tattgagcag ctgggaacac catcagcaga gttcatgaag aaacttcagc caactgtgag gaattatgtc gaaaacagac caaagtatcc tggaatcaaa tttgaagaac tctttccaga ttggatattc ccatcagaat ctgagcgaga caaaataaaa acaagtcaag ccagagatct gttatcaaaa atgttagtga ttgatcctga caagcggatc tctgtagacg aagctctgcg tcacccatac atcactgttt ggtatgaccc cgccgaagca gaagccccac cacctcaaat ttatgatgcc cagttggaag aaagagaaca tgcaattgaa gaatggaaag agctaattta caaagaagtc atggattggg aagaaagaag caagaatggt gttgtaaaag atcagccttc agatgcagca gtaagtagca acgccactcc ttctcagtct tcatcgatca atgacatttc atccatgtcc actgagcaga cgctggcctc agacacagac agcagtcttg atgcctcgac gggacccctt gaaggctgtc gatga

Molecular Weight

27,334 Da

OMIM

602896

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MAPK9 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPK9. It may not necessarily be applicable to this product.

NCBI GI #

21618469

NCBI GeneID

5601

NCBI Accession #

BC032539

UniProt Secondary Accession #

Q15708; Q15710; Q15711; Q8N5C5; A8K0S3; B5BU66; B5M0B4; D3DWQ8; D3DWQ9

UniProt Related Accession #

P45984

NCBI Official Full Name

Homo sapiens mitogen-activated protein kinase 9, mRNA

NCBI Official Synonym Full Names

mitogen-activated protein kinase 9

NCBI Official Symbol

MAPK9

NCBI Official Synonym Symbols

JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA

UniProt Protein Name

Mitogen-activated protein kinase 9

UniProt Synonym Protein Names

JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2

UniProt Gene Name

MAPK9

UniProt Synonym Gene Names

JNK2; PRKM9; SAPK1A; MAP kinase 9; MAPK 9; SAPK1a

UniProt Entry Name

MK09_HUMAN

NCBI Protein Information

mitogen-activated protein kinase 9

NCBI Summary for MAPK9

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]

UniProt Comments for MAPK9

JNK2: a protein kinase of the MAPK family that is potently activated by a variety of environmental stresses including UV radiation. Phosphorylates specific transcription factors such as c-Jun and ATF2, mediating immediate-early gene expression. Closely related to JNK1. Both are involved in UV radiation induced apoptosis. Blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells in the mouse. Four alternatively-spliced isoforms have been described.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CMGC; EC 2.7.11.24; CMGC group; MAPK family; MAPK/JNK subfamily; JNK subfamily

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: cytosol; nucleoplasm

Molecular Function: JUN kinase activity; protein binding; transcription factor binding

Biological Process: JNK cascade; protein amino acid phosphorylation; regulation of circadian rhythm; regulation of transcription factor activity; response to stress

Research Articles on MAPK9

1. Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis through P38 MAPK and JNK1/2 pathways, and therefore may prove to be an adjuvant to the treatment of non-small cell lung cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MAPK9 cdna clone

Products by Pathway	Pathway Diagram
AGE/RAGE Pathway antibodies	AGE/RAGE Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies	Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
Adipocytokine Signaling Pathway antibodies	Adipocytokine Signaling Pathway Diagram
Adipocytokine Signaling Pathway antibodies	Adipocytokine Signaling Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
CD40/CD40L Signaling Pathway antibodies	CD40/CD40L Signaling Pathway Diagram
CDC42 Signaling Events Pathway antibodies	CDC42 Signaling Events Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram

Diseases associated with MAPK9 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with MAPK9 and Neoplasms
Inflammation Antibodies	>3 publications with MAPK9 and Inflammation
Breast Neoplasms Antibodies	>2 publications with MAPK9 and Breast Neoplasms
Pancreatic Neoplasms Antibodies	>1 publications with MAPK9 and Pancreatic Neoplasms
Lung Diseases Antibodies	>1 publications with MAPK9 and Lung Diseases
Lung Neoplasms Antibodies	>1 publications with MAPK9 and Lung Neoplasms
Edema Antibodies	>1 publications with MAPK9 and Edema
Acute Kidney Injury Antibodies	>1 publications with MAPK9 and Acute Kidney Injury
Necrosis Antibodies	>1 publications with MAPK9 and Necrosis

Organs/Tissues associated with MAPK9 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with MAPK9 and Blood
Lung Antibodies	>3 publications with MAPK9 and Lung
Vascular Antibodies	>2 publications with MAPK9 and Vascular
Muscle Antibodies	>2 publications with MAPK9 and Muscle
Kidney Antibodies	>2 publications with MAPK9 and Kidney
Prostate Antibodies	>1 publications with MAPK9 and Prostate
Mammary Gland Antibodies	>1 publications with MAPK9 and Mammary Gland
Pancreas Antibodies	>1 publications with MAPK9 and Pancreas
Intestine Antibodies	>1 publications with MAPK9 and Intestine
Brain Antibodies	>1 publications with MAPK9 and Brain