Human MFSD8 cDNA Clone Expression Plasmid – Cat# MBS1269366

MFSD8 cDNA Clone – Major Facilitator Superfamily Domain Containing 8 (Human)

Name: MFSD8 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269366
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269366

MBS1269366 is a cDNA clone targeting MFSD8. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MFSD8, cDNA Clone

Full Product Name

MFSD8 cDNA Clone

Product Gene Name

MFSD8 cdna clone

Sequence

atggccggcc tgcggaacga aagtgaacag gagccgctct taggcgacac acctggaagc agagaatggg acattttaga gactgaagag cattataaga gccgatggag atctattagg attttatatc ttactatgtt tctcagcagt gtagggtttt ctgtagtgat gatgtccata tggccatatc tccaaaagat tgatccgaca gctgatacaa gttttttggg ctgggttatt gcttcatata gtcttggcca aatggtagct tcacctatat ttggtttatg gtctaattat agaccaagaa aagagcctct tattgtctcc atcttgattt ccgtggcagc caactgcctc tatgcatatc tccacatccc agcttctcat aataaatact acatgctggt tgctcgtgga ttgttgggaa ttggagcagg aaatgtagca gttgttagat catatactgc tggtgctact tcccttcagg aaagaacaag ttccatggca aacataagca tgtgtcaagc attaggtttt attctaggtc cagtttttca gacttgtttt acattccttg gagaaaaagg tgtgacatgg gatgtgatta aactgcagat aaacatgtat acaacaccag ttttacttag cgccttcctg ggaattttaa atattattct gatccttgcc atactaagag aacatcgtgt ggatgactca ggaagacagt gtaaaagtat taattttgaa gaagcaagta cagatgaagc tcaggttccc caaggaaata ttgaccaggt tgctgttgtg gccatcaatg ttctgttttt tgtgactcta tttatctttg ccctttttga aaccatcatt actccattaa caatggatat gtatgcctgg actcaagaac aagctgtgtt atataatggc ataatacttg ctgctcttgg ggttgaagcc gttgttattt tcttaggagt taagttgctt tccaaaaaga ttggcgagcg tgctattcta ctgggaggac tcatcgttgt atgggttggc ttctttatct tgttaccttg gggaaatcaa tttcccaaaa tacagtggga agatttgcac aataattcaa tccctaatac cacatttggg gaaattatta ttggtctttg gaagtctcca atggaagatg acaatgaaag accaactggt tgctcgattg aacaagcctg gtgcctctac accccggtga ttcatctggc ccagttcctt acatcagctg tgctaatagg attaggctat ccagtctgca atcttatgtc ctatactcta tattcaaaaa ttctaggacc aaaacctcag ggtgtataca tgggctggtt aacagcatct ggaagtggag cccggattct tgggcctatg ttcatcagcc aagtgtatgc tcactgggga ccacgatggg cattcagcct ggtgtgtgga ataatagtgc tcaccatcac cctcctggga gtggtttaca aaagactcat tgctctttct gtaagatatg ggaggattca ggaataa

Molecular Weight

17,092 Da

OMIM

610951

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MFSD8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MFSD8. It may not necessarily be applicable to this product.

NCBI GI #

20810270

NCBI GeneID

256471

NCBI Accession #

BC029503

UniProt Secondary Accession #

Q8N2P3; B2RDM1; B7Z205

UniProt Related Accession #

Q8NHS3

NCBI Official Full Name

Homo sapiens major facilitator superfamily domain containing 8, mRNA

NCBI Official Synonym Full Names

major facilitator superfamily domain containing 8

NCBI Official Symbol

MFSD8

NCBI Official Synonym Symbols

CCMD; CLN7

UniProt Protein Name

Major facilitator superfamily domain-containing protein 8

UniProt Synonym Protein Names

Ceroid-lipofuscinosis neuronal protein 7

Protein Family

Major facilitator superfamily domain-containing protein

UniProt Gene Name

MFSD8

UniProt Synonym Gene Names

CLN7

UniProt Entry Name

MFSD8_HUMAN

NCBI Protein Information

major facilitator superfamily domain-containing protein 8

NCBI Summary for MFSD8

This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008]

UniProt Comments for MFSD8

MFSD8: May be a carrier that transport small solutes by using chemiosmotic ion gradients (Potential). Defects in MFSD8 are the cause of neuronal ceroid lipofuscinosis type 7 (CLN7). A form of late infantile neuronal ceroid lipofuscinosis. CNL are a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by the intracellular accumulation of autofluorescent lipopigment storage material in different patterns ultrastructurally. The patterns most often observed CLN7 are mixed combinations of granular, curvilinear, fingerprint, and rectilinear profiles. The clinical course includes progressive dementia, seizures, and progressive visual failure. Belongs to the major facilitator superfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q28.2

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; nucleoplasm

Disease: Ceroid Lipofuscinosis, Neuronal, 7; Macular Dystrophy With Central Cone Involvement

Research Articles on MFSD8

1. MFSD8 genetic testing should also be considered in patients with Rett like phenotype at onset and negative MECP2 mutation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MFSD8 cdna clone

Products by Pathway	Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram

Diseases associated with MFSD8 cdna clone

Disease Name	Pubmed Publications
Neurodegenerative Diseases Antibodies	>11 publications with MFSD8 and Neurodegenerative Diseases
Ceroid Lipofuscinosis, Neuronal, 7 Antibodies	>4 publications with MFSD8 and Ceroid Lipofuscinosis, Neuronal, 7

Organs/Tissues associated with MFSD8 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with MFSD8 and Brain
Blood Antibodies	>1 publications with MFSD8 and Blood
Kidney Antibodies	>1 publications with MFSD8 and Kidney