Human MINPP1 cDNA Clone Expression Plasmid – Cat# MBS1277517

MINPP1 cDNA Clone – Multiple Inositol Polyphosphate Histidine Phosphatase, 1 (Human)

Name: MINPP1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1277517
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277517

MBS1277517 is a cDNA clone targeting MINPP1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MINPP1, cDNA Clone

Full Product Name

MINPP1 cDNA Clone

Product Gene Name

MINPP1 cdna clone

Sequence

atgctacgcg cgcccggctg cctcctccgg acctccgtag cgcctgccgc ggccctggct gcggcgctgc tctcgtcgct tgcgcgctgc tctcttctag agccgaggga cccggtggcc tcgtcgctca gcccctattt cggcaccaag actcgctacg aggatgtcaa ccccgtgcta ttgtcgggcc ccgaggctcc gtggcgggac cctgagctgc tggaggggac ctgcaccccg gtgcagctgg tcgccctcat tcgccacggc acccgctacc ccacggtcaa acagatccgc aagctgaggc agctgcacgg gttgctgcag gcccgcgggt ccagggatgg cggggctagt agtaccggca gccgcgacct gggtgcagcg ctggccgact ggcctttgtg gtacgcggac tggatggacg ggcagctagt agagaaggga cggcaggata tgcgacagct ggcgctgcgt ctggcctcgc tcttcccggc ccttttcagc cgtgagaact acggccgcct gcggctcatc accagttcca agcaccgctg catggatagc agcgccgcct tcctgcaggg gctgtggcag cactaccacc ctggcttgcc gccgccggac gtcgcagata tggagtttgg acctccaaca gttaatgata aactaatgag attttttgat cactgtgaga agtttttaac tgaagtagaa aaaaatgcta cagctcttta tcacgtggaa gccttcaaaa ctggaccaga aatgcagaac attttaaaaa aagttgcagc tactttgcaa gtgccagtaa atgatttaaa tgcagattta attcaagtag cctttttcac ctgttcattt gacctggcaa ttaaaggtgt taaatctcct tggtgtgatg tttttgacat agatgatgca aaggtattag aatatttaaa tgatctgaaa caatattgga aaagaggata tgggtatact attaacagtc gatccagctg caccttgttt caggatatct ttcagcactt ggacaaagca gttgaacaga aacaaaggtc tcagccaatt tcttctccag tcatcctcca gtttggtcat gcagagactc ttcttccact gctttctctc atgggctact tcaaagacaa ggaaccccta acagcgtaca attacaaaaa acaaatgcat cggaagttcc gaagtggtct cattgtacct tatgcctcga acctgatatt tgtgctttac cactgtgaaa atgctaagac tcctaaagaa caattccgag tgcagatgtt attaaatgaa aaggtgttac ctttggctta ctcacaagaa actgtttcat tttatgaaga tctgaagaac cactacaagg acatccttca gagttgtcaa accagtgaag aatgtgaatt agcaagggct aacagtacat ctgatgaact atga

Molecular Weight

33,100 Da

OMIM

188470

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MINPP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MINPP1. It may not necessarily be applicable to this product.

NCBI GI #

21619737

NCBI GeneID

9562

NCBI Accession #

BC032504

UniProt Secondary Accession #

O95172; O95286; Q59EJ2; Q9UGA3; F5H683

UniProt Related Accession #

Q9UNW1

NCBI Official Full Name

Homo sapiens multiple inositol polyphosphate histidine phosphatase, 1, mRNA

NCBI Official Synonym Full Names

multiple inositol-polyphosphate phosphatase 1

NCBI Official Symbol

MINPP1

NCBI Official Synonym Symbols

MIPP; HIPER1; MINPP2

UniProt Protein Name

Multiple inositol polyphosphate phosphatase 1

UniProt Synonym Protein Names

2,3-bisphosphoglycerate 3-phosphatase (EC:3.1.3.80); 2,3-BPG phosphatase; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase

Protein Family

Multiple inositol polyphosphate phosphatase

UniProt Gene Name

MINPP1

UniProt Synonym Gene Names

MIPP; 2,3-BPG phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase

UniProt Entry Name

MINP1_HUMAN

NCBI Protein Information

multiple inositol polyphosphate phosphatase 1

NCBI Summary for MINPP1

This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]

UniProt Comments for MINPP1

MINPP1: Acts as a phosphoinositide 5- and phosphoinositide 6- phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3- phosphoglycerate. May play a role in bone development (endochondral ossification). Defects in MINPP1 may be involved in follicular thyroid tumors development. Belongs to the histidine acid phosphatase family. MINPP1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.1.3.62; Carbohydrate Metabolism - inositol phosphate; Secreted, signal peptide; Secreted; EC 3.1.3.80; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q23

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen

Molecular Function: inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; phosphohistidine phosphatase activity

Biological Process: inositol phosphate metabolic process; polyphosphate metabolic process

Disease: Thyroid Carcinoma, Follicular

Research Articles on MINPP1

1. By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MINPP1 cdna clone

Products by Pathway	Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Rapoport-Luebering Glycolytic Shunt Pathway antibodies	Rapoport-Luebering Glycolytic Shunt Pathway Diagram
Rapoport-Luebering Glycolytic Shunt Pathway antibodies	Rapoport-Luebering Glycolytic Shunt Pathway Diagram

Diseases associated with MINPP1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with MINPP1 and Neoplasms
Genital Diseases, Male Antibodies	>1 publications with MINPP1 and Genital Diseases, Male
Hypertrophy Antibodies	>1 publications with MINPP1 and Hypertrophy
Thyroid cancer, follicular Antibodies	>1 publications with MINPP1 and Thyroid cancer, follicular

Organs/Tissues associated with MINPP1 cdna clone

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>2 publications with MINPP1 and Bone
Prostate Antibodies	>1 publications with MINPP1 and Prostate
Embryonic Tissue Antibodies	>1 publications with MINPP1 and Embryonic Tissue