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MLLT11 cDNA Clone – Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 11 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276490

MBS1276490 is a cDNA clone targeting MLLT11. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MLLT11, cDNA Clone
Full Product Name
MLLT11 cDNA Clone
Product Gene Name
Sequence
atgagggacc ctgtgagtag ccagtacagt tcctttcttt tctggaggat gcccatccca gaactggatc tgtcggagct ggaaggcctg ggtctgtcag atacagccac ctacaaggtc aaagacagca gcgttggcaa aatgatcggg caagcaactg cagcagacca ggagaaaaac cctgaaggtg atggcctcct tgagtacagc accttcaact tctggagagc tcccattgcc agcatccact ccttcgaact ggacttgctc taa
Molecular Weight
10,061 Da
OMIM
604684
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MLLT11 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MLLT11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11, mRNA
NCBI Official Synonym Full Names
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
NCBI Official Symbol
MLLT11
NCBI Official Synonym Symbols
AF1Q
UniProt Protein Name
Protein AF1q
Protein Family
UniProt Gene Name
MLLT11
UniProt Synonym Gene Names
AF1Q
UniProt Entry Name
AF1Q_HUMAN
NCBI Protein Information
protein AF1q

NCBI Summary for MLLT11

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
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UniProt Comments for MLLT11

MLLT11: a protein that is highly expressed in thymus and leukemic cell lines. A chromosomal aberration involving MLLT11 is found in acute leukemias. Translocation t(1;11)(q21;q23) with MLL.

Protein type: Oncoprotein

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: intracellular

Biological Process: positive regulation of apoptosis; positive regulation of mitochondrial depolarization; positive regulation of transcription, DNA-dependent

Disease: Juvenile Myelomonocytic Leukemia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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