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MT2A cDNA Clone – Metallothionein-2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS201013

MT2A (Metallothionein 2A) belongs to lncRNA RNA class. Diseases associated with MT2A include cerebral lymphoma and prostate cancer. More details

$245 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MT2A, cDNA Clone
Full Product Name
MT2A
Product Gene Name
Product Synonym Names
MT2
Sequence
Nucleotide Sequence: ATGGATCCCA ACTGCTCCTG CGCCGCCGGT GACTCCTGCA CCTGCGCCGG CTCCTGCAAA TGCAAAGAGT GCAAATGCAC CTCCTGCAAG AAAAGCTGCT GCTCCTGCTG CCCTGTGGGC TGTGCCAAGT GTGCCCAGGG CTGCATCTGC AAAGGGGCGT CGGACAAGTG CAGCTGCTGC GCCTGA

Transl ation Sequence: MDPNCSCAAG DSCTCAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCIC KGASDKCSCC A
Form/Format
Lyophilized
Preparation and Storage
Store the plasmid at -20 degree C.
OMIM
156360
3D Structure
ModBase 3D Structure for P02795
Species
Human
Chromosome Location
16q13
OMIM Reference Number
156360
cDNA Size
186bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted Nde I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

Other Notes

Small volumes of MT2A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MT2A purchase

MBS201013 is a cDNA clone targeting MT2A.

Additional Details

NCBI/Uniprot data below describe general gene information for MT2A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metallothionein-2
NCBI Official Synonym Full Names
metallothionein 2A
NCBI Official Symbol
MT2A
NCBI Official Synonym Symbols
MT2; MT-2; MT-II
UniProt Protein Name
Metallothionein-2
UniProt Synonym Protein Names
Metallothionein-2A; Metallothionein-II
Protein Family
UniProt Gene Name
MT2A
UniProt Synonym Gene Names
CES1; MT2; MT-2; MT-II
UniProt Entry Name
MT2_HUMAN
NCBI Protein Information
metallothionein-2

NCBI Summary for MT2A

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
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UniProt Comments for MT2A

MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; zinc ion binding; drug binding

Biological Process: cellular copper ion homeostasis; cytokine and chemokine mediated signaling pathway; negative regulation of growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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