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MTHFS cDNA Clone – 5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274573

MBS1274573 is a cDNA clone targeting MTHFS. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTHFS, cDNA Clone
Full Product Name
MTHFS cDNA Clone
Product Gene Name
Sequence
atggcggcgg cagcggtgag cagcgccaag cgtagcctgc ggggagagct gaagcagcgt ctgcgggcga tgagtgccga ggagcggcta cgccagtccc gcgtactgag ccagaaggtg attgcccaca gtgagtatca aaagtccaaa agaatttcca tctttctgag catgcaagat gaaattgaga cagaagagat catcaaggac attttccaac gaggcaaaat ctgcttcatc cctcggtacc ggttccagag caatcacatg gatatggtga gaatagaatc accagaggaa atttctttac ttcccaaaac atcctggaat atccctcagc ctggtgaggg tgatgttcgg gaggaggcct tgtccacagg gggacttgat ctcatcttca tgccaggcct tgggtttgac aaacatggca accgactggg gaggggcaag ggctactatg atgcctatct gaagcgctgt ttgcagcatc aggaagtgaa gccctacacc ctggcgttgg ctttcaaaga acagatttgc ctccaggtcc cagtgaatga aaacgacatg aaggtagatg aagtccttta cgaagactcg tcaacagctt aa
Molecular Weight
20,519 Da
OMIM
604197
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MTHFS cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MTHFS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase), mRNA
NCBI Official Synonym Full Names
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCBI Official Symbol
MTHFS
NCBI Official Synonym Symbols
HsT19268
UniProt Protein Name
5-formyltetrahydrofolate cyclo-ligase
UniProt Synonym Protein Names
5,10-methenyl-tetrahydrofolate synthetase; MTHFS; Methenyl-THF synthetase
UniProt Gene Name
MTHFS
UniProt Synonym Gene Names
MTHFS; Methenyl-THF synthetase
UniProt Entry Name
MTHFS_HUMAN
NCBI Protein Information
5-formyltetrahydrofolate cyclo-ligase

NCBI Summary for MTHFS

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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UniProt Comments for MTHFS

Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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