Human NDUFS3 cDNA Clone Expression Plasmid – Cat# MBS1270949

NDUFS3 cDNA Clone – NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (Human)

Name: NDUFS3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270949
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270949

MBS1270949 is a cDNA clone targeting NDUFS3. More details

$350 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NDUFS3, cDNA Clone

Full Product Name

NDUFS3 cDNA Clone

Product Gene Name

NDUFS3 cdna clone

Sequence

atggcggcgg cggcggtagc caggctgtgg tggcgcggga tcttgggggc ctcggcgctg accaggggga ctgggcgacc ctccgttctg ttgctgccgg tgaggcggga gagcgccggg gccgacacgc gccccactgt cagaccacgg aatgatgtgg cccacaagca gctctcagct tttggagagt atgtggctga aatcttgccc aagtatgtcc aacaagttca ggtgtcctgc ttcaatgagt tagaggtctg tatccatcct gatggcgtca tcccagtgct gactttcctc agggatcaca ccaatgcaca gttcaaatct ctggttgact tgacagcagt ggacgtccca actcggcaaa accgttttga gattgtctac aacctgttgt ctctgcgctt caactcacgg atccgtgtga agacctacac agatgagctg acgcccattg agtctgctgt ctctgtgttc aaggcagcca actggtatga aagggagatc tgggacatgt ttggagtctt ctttgctaac caccctgatc taagaaggat cctgacagat tatggcttcg agggacatcc tttccggaaa gactttcctc tatctggcta tgttgagtta cgttatgatg atgaagtgaa gcgggtggtg gcagagccgg tggagttggc ccaagagttc cgcaaatttg acctgaacag cccctgggag gctttcccag tctatcgcca acccccggag agtctcaagc ttgaagccgg agacaagaag cctgatgcca agtag

Molecular Weight

14,679 Da

OMIM

603846

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NDUFS3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFS3. It may not necessarily be applicable to this product.

NCBI GI #

37588978

NCBI GeneID

4722

NCBI Accession #

BC000617

UniProt Secondary Accession #

Q9UNQ8; B2R9J1; B4DFM8

UniProt Related Accession #

O75489

NCBI Official Full Name

Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase), mRNA

NCBI Official Synonym Full Names

NADH:ubiquinone oxidoreductase core subunit S3

NCBI Official Symbol

NDUFS3

NCBI Official Synonym Symbols

CI-30

UniProt Protein Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

UniProt Synonym Protein Names

Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit

UniProt Gene Name

NDUFS3

UniProt Synonym Gene Names

CI-30kD

UniProt Entry Name

NDUS3_HUMAN

NCBI Protein Information

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

NCBI Summary for NDUFS3

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

UniProt Comments for NDUFS3

NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 1.6.99.3; Mitochondrial; Oxidoreductase; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 11p11.11

Cellular Component: mitochondrial matrix; mitochondrial membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleus

Molecular Function: NADH dehydrogenase activity; protein binding

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; negative regulation of cell growth; substantia nigra development

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

Research Articles on NDUFS3

1. High NDUFS3 expression is associated with IgA nephropathy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NDUFS3 cdna clone

Products by Pathway	Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Electron Transport Chain Pathway antibodies	Electron Transport Chain Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway antibodies	NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram

Diseases associated with NDUFS3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>11 publications with NDUFS3 and Neoplasms
Death Antibodies	>9 publications with NDUFS3 and Death
Nervous System Diseases Antibodies	>6 publications with NDUFS3 and Nervous System Diseases
Brain Diseases Antibodies	>5 publications with NDUFS3 and Brain Diseases
Diabetes Mellitus Antibodies	>4 publications with NDUFS3 and Diabetes Mellitus
Breast Neoplasms Antibodies	>4 publications with NDUFS3 and Breast Neoplasms
Drug Toxicity Antibodies	>3 publications with NDUFS3 and Drug Toxicity
Kidney Diseases Antibodies	>3 publications with NDUFS3 and Kidney Diseases
Inflammation Antibodies	>1 publications with NDUFS3 and Inflammation
Necrosis Antibodies	>1 publications with NDUFS3 and Necrosis

Organs/Tissues associated with NDUFS3 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>7 publications with NDUFS3 and Blood
Kidney Antibodies	>6 publications with NDUFS3 and Kidney
Brain Antibodies	>5 publications with NDUFS3 and Brain
Muscle Antibodies	>2 publications with NDUFS3 and Muscle
Embryonic Tissue Antibodies	>2 publications with NDUFS3 and Embryonic Tissue
Adipose Tissue Antibodies	>1 publications with NDUFS3 and Adipose Tissue
Heart Antibodies	>1 publications with NDUFS3 and Heart
Connective Tissue Antibodies	>1 publications with NDUFS3 and Connective Tissue
Liver Antibodies	>1 publications with NDUFS3 and Liver