Human NFAT5 cDNA Clone Expression Plasmid – Cat# MBS1272733

NFAT5 cDNA Clone – Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (Human)

Name: NFAT5 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272733
Price: 2160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272733

MBS1272733 is a cDNA clone targeting NFAT5. More details

$2160 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NFAT5, cDNA Clone

Full Product Name

NFAT5 cDNA Clone

Product Gene Name

NFAT5 cdna clone

Sequence

ATGCCCTCGG ACTTCATCTC ATTGCTCAGC GCGGACCTAG ACCTGGAATC GCCCAAGTCC CTCTACTCGC GAGATTCTCT GAAGTTACAC CCATCACAGA ATTTTCATAG AGCTGGACTA TTGGAAGAAT CTGTCTATGA TCTTCTCCCA AAGGAGTTAC AGTTACCTCC ATCTAGAGAA ACATCTGTAG CATCAATGAG TCAGACAAGC GGTGGTGAGG CAGGCTCGCC TCCTCCAGCT GTTGTTGCTG CTGATGCTTC TTCAGCTCCC TCCTCTTCCT CCATGGGCGG TGCTTGCAGC TCCTTTACCA CCTCTTCCAG CCCTACCATT TATTCTACCT CAGTCACCGA CAGCAAGGCT ATGCAAGTGG AGAGCTGCTC CTCAGCCGTG GGGGTAAGTA ACAGAGGGGT AAGTGAAAAG CAGTTAACCA GTAACACAGT TCAGCAGCAT CCATCAACAC CGAAGAGGCA CACAGTCTTG TACATCTCAC CACCACCTGA GGACTTGCTG GATAACAGTC GGATGTCCTG CCAGGATGAG GGGTGTGGAT TGGAATCTGA GCAGAGCTGC AGTATGTGGA TGGAGGATTC CCCCTCCAAC TTCAGTAACA TGAGCACCAG TTCCTACAAT GATAACACTG AGGTACCTCG TAAATCACGA AAACGAAATC CAAAGCAGAG GCCGGGGGTC AAACGACGAG ATTGTGAAGA ATCTAATATG GATATATTTG ATGCCGACAG TGCCAAAGCA CCTCACTATG TGCTTTCTCA GCTTACCACG GACAACAAAG GCAACTCAAA AGCGGGAAAT GGAACATTGG AAAACCAAAA AGGAACTGGA GTAAAGAAGA GCCCTATGTT GTGTGGACAA TATCCTGTTA AAAGTGAGGG AAAGGAGCTG AAGATAGTTG TACAACCTGA GACACAGCAC CGAGCTCGGT ACCTGACTGA GGGCAGCCGT GGCTCAGTGA AAGATAGAAC ACAGCAAGGC TTTCCTACAG TAAAGCTGGA AGGCCATAAT GAACCTGTAG TGTTGCAAGT GTTTGTGGGC AACGACTCTG GACGAGTGAA ACCACATGGA TTTTATCAGG CCTGCAGAGT AACTGGACGA AATACAACTC CTTGCAAAGA AGTGGACATT GAAGGCACTA CTGTTATAGA AGTCGGCCTT GATCCTAGCA ACAACATGAC ACTGGCGGTG GACTGCGTAG GGATATTGAA ATTGAGGAAT GCTGATGTCG AAGCCAGAAT AGGAATTGCT GGTTCCAAGA AGAAAAGCAC TCGTGCCAGA TTGGTTTTTC GAGTTAATAT CATGAGGAAA GATGGCTCCA CTTTGACACT GCAAACACCC TCTTCTCCAA TTTTGTGTAC TCAGCCAGCA GGAGTGCCAG AAATCTTAAA GAAAAGCTTG CATAGCTGTT CAGTGAAAGG AGAAGAAGAA GTGTTTTTAA TCGGCAAGAA CTTTCTGAAA GGAACTAAAG TTATTTTCCA AGAAAATGTT TCTGATGAAA ACTCTTGGAA GTCAGAAGCT GAAATTGATA TGGAACTATT TCATCAGAAT CATCTTATTG TGAAGGTTCC TCCCTATCAT GACCAACATA TAACTTTGCC TGTGTCAGTG GGAATATATG TAGTGACAAA TGCTGGAAGA TCTCATGATG TTCAACCATT CACTTACACT CCAGACCCAG CAGCTGGTGC TTTGAATGTA AATGTGAAGA AGGAAATATC TAGTCCAGCA AGACCTTGCT CTTTTGAAGA GGCCATGAAA GCAATGAAAA CTACTGGATG TAATTTAGAT AAGGTAAATA TTATCCCTAA TGCCCTGATG ACTCCACTCA TACCAAGCAG TATGATTAAG AGTGAAGATG TTACTCCAAT GGAAGTAACA GCAGAAAAAA GATCTTCCAC TATTTTTAAG ACTACAAAGT CTGTTGGATC AACTCAGCAA ACATTAGAAA ACATCTCAAA CATAGCAGGA AATGGCTCTT TTTCATCACC ATCATCTTCC CACCTACCTT CTGAAAATGA AAAACAGCAG CAGATTCAGC CCAAGGCATA CAACCCAGAG ACCCTGACAA CTATTCAAAC CCAGGACATC TCACAGCCTG GTACTTTTCC AGCAGTTTCT GCTTCTAGTC AGCTGCCCAA CAGCGATGCA CTATTGCAGC AGGCTACACA GTTTCAGACA AGAGAAACTC AGTCTAGAGA GATATTACAG TCAGATGGTA CAGTGGTTAA TTTGTCACAA CTGACTGAGG CATCACAACA ACAGCAGCAG TCACCACTAC AAGAACAAGC ACAGACTTTA CAGCAGCAGA TTTCATCAAA TATTTTTCCA TCACCAAATA GTGTGAGTCA GCTTCAGAAT ACTATTCAGC AGCTGCAAGC AGGGAGTTTC ACAGGCAGTA CTGCTAGTGG CAGCAGTGGA AGTGTTGACT TGGTCCAACA AGTTTTAGAG GCACAGCAGC AGTTATCTTC AGTTTTATTT TCTGCTCCAG ATGGTAATGA GAATGTTCAA GAGCAGCTTA GTGCAGATAT TTTTCAACAA GTCAGTCAAA TTCAGAGTGG TGTAAGCCCT GGAATGTTTT CCTCAACAGA GCCAACAGTC CATACCAGAC CAGATAATTT ATTACCTGGA AGAGCTGAAA GTGTTCATCC ACAGTCTGAA AACACGTTAT CTAATCAACA GCAGCAGCAG CAGCAGCAAC AGCAAGTGAT GGAATCTTCA GCCGCAATGG TGATGGAGAT GCAACAGAGT ATCTGCCAGG CAGCTGCCCA GATTCAGTCA GAGTTATTCC CTTCAACTGC TTCAGCAAAT GGAAACCTTC AGCAATCGCC AGTTTACCAG CAGACTTCTC ACATGATGAG TGCATTGTCT ACCAATGAGG ATATGCAAAT GCAGTGTGAA TTGTTTTCTT CTCCTCCTGC AGTTTCTGGA AATGAAACTT CTACAACTAC CACACAGCAG GTTGCAACCC CTGGCACTAC CATGTTTCAG ACATCAAGTT CAGGAGATGG AGAAGAAACT GGAACACAAG CAAAACAGAT TCAGAACAGT GTCTTTCAGA CCATGGTCCA AATGCAACAT AGTGGGGACA ATCAACCTCA AGTTAACCTT TTTTCATCCA CAAAAAGTAT GATGAGTGTT CAGAATAGTG GTACCCAACA ACAAGGTAAT GGTTTATTCC AGCAAGGGAA TGAGATGATG TCACTTCAAT CTGGAAATTT TTTGCAGCAG TCTTCTCATT CACAGGCCCA ACTTTTTCAT CCTCAAAATC CTATTGCCGA TGCTCAGAAC CTTTCCCAGG AAACTCAAGG TTCTCTCTTT CATAGTCCAA ATCCTATTGT CCACAGTCAG ACTTCTACAA CCTCCTCTGA ACAAATGCAG CCTCCAATGT TTCACTCTCA AAGTACCATT GCTGTGTTAC AGGGCTCTTC AGTTCCTCAA GACCAGCAGT CAACCAACAT ATTTCTTTCC CAGAGTCCCA TGAATAATCT TCAGACTAAC ACAGTAGCCC AAGAAGCATT TTTTGCAGCA CCGAACTCAA TTTCTCCACT TCAGTCAACA TCAAACAGTG AACAACAAGC TGCTTTCCAA CAGCAAGCTC CAATATCACA CATCCAGACT CCTATGCTTT CCCAAGAACA GGCACAACCC CCGCAGCAGG GTTTATTTCA GCCTCAGGTG GCCCTGGGCT CCCTTCCACC TAATCCAATG CCTCAAAGCC AACAAGGAAC CATGTTCCAG TCACAGCACT CAATAGTTGC CATGCAGAGT AACTCTCCAT CCCAGGAACA GCAGCAGCAG CAGCAACAGC AGCAGCAACA GCAGCAGCAA CAACAACAGA GCATTTTATT CAGTAATCAG AATACCATGG CTACAATGGC GTCTCCAAAG CAACCACCAC CAAACATGAT ATTCAACCCA AATCAAAATC CAATGGCTAA TCAGGAGCAA CAGAACCAGT CAATTTTTCA CCAACAAAGT AACATGGCCC CAATGAATCA AGAGCAACAG CCCATGCAAT TTCAGAGTCA GTCCACAGTT TCCTCACTTC AGAACCCAGG TCCTACCCAG TCGGAATCAT CACAGACCCC CTTGTTCCAT AGCTCTCCTC AGATTCAGTT GGTACAAGGG TCACCTAGTT CTCAAGAGCA GCAAGTAACT CTCTTCTTAT CTCCAGCATC CATGTCTGCC TTGCAGACCA GTATAAATCA ACAAGATATG CAACAGTCTC CTCTTTATTC CCCTCAGAAC AACATGCCTG GAATTCAAGG AGCCACATCT TCGCCTCAAC CACAGGCTAC TTTATTTCAC AACACAGCAG GAGGCACAAT GAACCAACTG CAGAATTCTC CTGGCTCATC TCAGCAGACA TCAGGAATGT TCTTATTTGG CATTCAAAAT AACTGTAGTC AGCTTTTAAC CTCTGGACCA GCTACATTGC CTGATCAGTT GATGGCCATA AGTCAGCCAG GCCAACCACA AAACGAGGGC CAGCCACCTG TGACAACACT TCTTTCTCAG CAAATGCCAG AGAATTCTCC ACTGGCATCC TCTATAAACA CCAACCAGAA CATCGAAAAG ATTGATTTGC TTGTTTCATT GCAAAACCAA GGGAACAACT TGACTGGCTC CTTTTAA

Molecular Weight

167,808 Da

OMIM

604708

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NFAT5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFAT5. It may not necessarily be applicable to this product.

NCBI GI #

124297940

NCBI GeneID

10725

NCBI Accession #

BC131509

UniProt Secondary Accession #

O95693; Q7LA65; Q969Q8; Q96QH3; Q9UN18; A2RRB4; A6H8V5; E9PHR7

UniProt Related Accession #

O94916

NCBI Official Full Name

Homo sapiens nuclear factor of activated T-cells 5, tonicity-responsive, mRNA

NCBI Official Synonym Full Names

nuclear factor of activated T-cells 5

NCBI Official Symbol

NFAT5

NCBI Official Synonym Symbols

NFATZ; OREBP; NF-AT5; NFATL1; TONEBP

UniProt Protein Name

Nuclear factor of activated T-cells 5

UniProt Synonym Protein Names

T-cell transcription factor NFAT5; Tonicity-responsive enhancer-binding protein; TonE-binding protein; TonEBP

Protein Family

Nuclear factor of activated T-cells

UniProt Gene Name

NFAT5

UniProt Synonym Gene Names

KIAA0827; TONEBP; NF-AT5; TonE-binding protein; TonEBP

UniProt Entry Name

NFAT5_HUMAN

NCBI Protein Information

nuclear factor of activated T-cells 5

NCBI Summary for NFAT5

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for NFAT5

NFAT5: Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. Homodimer when bound to DNA, completely encircles its DNA target. Does not bind with Fos and Jun transcription factors. Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: excretion; positive regulation of transcription from RNA polymerase II promoter

Research Articles on NFAT5

1. Additionally, in peritoneal dialysis the cells of the peritoneal cavity are repeatedly exposed to a rise and fall in osmotic concentrations. Here we review the current information about NFAT5 in uremic patients and patients on peritoneal dialysis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NFAT5 cdna clone

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
B Cell Receptor Signaling Pathway antibodies	B Cell Receptor Signaling Pathway Diagram
B Cell Receptor Signaling Pathway antibodies	B Cell Receptor Signaling Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Hepatitis B Pathway antibodies	Hepatitis B Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
T Cell Receptor Signaling Pathway antibodies	T Cell Receptor Signaling Pathway Diagram

Diseases associated with NFAT5 cdna clone

Disease Name	Pubmed Publications
Death Antibodies	>19 publications with NFAT5 and Death
Neoplasms Antibodies	>14 publications with NFAT5 and Neoplasms
Necrosis Antibodies	>14 publications with NFAT5 and Necrosis
Inflammation Antibodies	>8 publications with NFAT5 and Inflammation
Nervous System Diseases Antibodies	>7 publications with NFAT5 and Nervous System Diseases
Drug Toxicity Antibodies	>6 publications with NFAT5 and Drug Toxicity
Hypertension Antibodies	>6 publications with NFAT5 and Hypertension
Brain Diseases Antibodies	>6 publications with NFAT5 and Brain Diseases
Kidney Diseases Antibodies	>6 publications with NFAT5 and Kidney Diseases
Disease Models, Animal Antibodies	>5 publications with NFAT5 and Disease Models, Animal

Organs/Tissues associated with NFAT5 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>62 publications with NFAT5 and Kidney
Blood Antibodies	>38 publications with NFAT5 and Blood
Heart Antibodies	>18 publications with NFAT5 and Heart
Lung Antibodies	>13 publications with NFAT5 and Lung
Muscle Antibodies	>13 publications with NFAT5 and Muscle
Brain Antibodies	>13 publications with NFAT5 and Brain
Embryonic Tissue Antibodies	>10 publications with NFAT5 and Embryonic Tissue
Vascular Antibodies	>9 publications with NFAT5 and Vascular
Liver Antibodies	>9 publications with NFAT5 and Liver
Bone Antibodies	>8 publications with NFAT5 and Bone