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NFIB cDNA Clone – Nuclear Factor I/B (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276365

MBS1276365 is a cDNA clone targeting NFIB. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NFIB, cDNA Clone
Full Product Name
NFIB cDNA Clone
Product Gene Name
NFIB cdna clone
Sequence
atgatgtatt ctcccatctg tctcactcag gatgaatttc acccattcat cgaggcactt cttccacatg tccgtgcaat tgcctatact tggttcaacc tgcaggctcg aaaacgcaag tactttaaaa agcatgagaa gcgaatgtca aaggatgaag aaagagcagt caaagatgag cttctcagtg aaaagcctga aatcaaacag aagtgggcat ccaggctcct tgccaaactg cgcaaagata ttcgccagga gtatcgagag gactttgtgc tcaccgtgac tggcaagaag cacccgtgct gtgtcttatc caatcccgac cagaagggta agattaggag aatcgactgc ctgcgacagg cagacaaagt ctggcgtctg gatctagtca tggtgatcct gttcaaaggc atccccttgg aaagtaccga tggagagcgg ctcatgaaat ccccacattg cacaaaccca gcactttgtg tccagccaca tcatatcaca gtatcagtta aggagcttga tttgtttttg gcatactacg tgcaggagca agattctgga caatcaggaa gtccaagcca caatgatcct gccaagaatc ctccaggtta ccttgaggat agttttgtaa aatctggagt cttcaatgta tcagaacttg taagagtatc cagaacgccc ataacccagg gaactggagt caacttccca attggagaaa tcccaagcca accatactat catgacatga actcgggggt caatcttcag aggtctctgt cttctccacc aagcagcaaa agacccaaaa ctatatccat agatgaaaat atggaaccaa gtcctacagg agacttttac ccctctccaa gttcaccagc tgctggaagt cgaacatggc acgaaagaga tcaagatatg tcttctccga ctactatgaa gaagcctgaa aagccattgt tcagctctgc atctccacag gattcttccc caagactgag cactttcccc cagcaccacc atcccggaat acctggagtt gcacacagtg tcatctcaac tcgaactcca cctccacctt caccgttgcc atttccaaca caagctatcc ttcctccagc cccatcgagc tacttttctc atccaacaat cagatatcct ccccacctga atcctcagga tactctgaag aactatgtac cttcttatga cccatccagt ccacaaacca gccagtcctg gtacctgggc tag
Molecular Weight
33,525 Da
OMIM
600728
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NFIB cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFIB. It may not necessarily be applicable to this product.

NCBI GI #
12654878
NCBI GeneID
4781
NCBI Accession #
BC001283
UniProt Secondary Accession #
O00166; Q12858; Q5VW29; Q63HM5; Q6ZNF9; Q96J45; G3V1P1; H7BYE8
UniProt Related Accession #
O00712
NCBI Official Full Name
Homo sapiens nuclear factor I/B, mRNA
NCBI Official Synonym Full Names
nuclear factor I B
NCBI Official Symbol
NFIB
NCBI Official Synonym Symbols
CTF; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB
UniProt Protein Name
Nuclear factor 1 B-type
UniProt Synonym Protein Names
CCAAT-box-binding transcription factor; CTF; Nuclear factor I/B; NF-I/B; NFI-B; TGGCA-binding protein
Protein Family
Nuclear factor
UniProt Gene Name
NFIB
UniProt Synonym Gene Names
NF1-B; Nuclear factor 1/B; CTF; NF-I/B; NFI-B
UniProt Entry Name
NFIB_HUMAN
NCBI Protein Information
nuclear factor 1 B-type

UniProt Comments for NFIB

NFI-B: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: nucleolus; nucleus

Molecular Function: DNA binding

Biological Process: anterior commissure morphogenesis; chondrocyte differentiation; glial cell differentiation; pontine nucleus development; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on NFIB

1. In benign prostatic hyperplasia, luminal NFIB loss correlated with more severe disease. in androgen-dependent LNCaP prostate cancer cells demonstrated that 64.3% of NFIB binding sites are associated with AR and FOXA1 binding sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NFIB cdna clone

 Products by Pathway  Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Termination Pathway antibodies  RNA Polymerase III Transcription Termination Pathway Diagram

Diseases associated with NFIB cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >36 publications with NFIB and Neoplasms
 Carcinoma Antibodies  >28 publications with NFIB and Carcinoma
 Adenocarcinoma Antibodies  >18 publications with NFIB and Adenocarcinoma
 Breast Neoplasms Antibodies  >12 publications with NFIB and Breast Neoplasms
 Nervous System Diseases Antibodies  >4 publications with NFIB and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >3 publications with NFIB and Neoplasms, Experimental
 Carcinoma, Squamous Cell Antibodies  >2 publications with NFIB and Carcinoma, Squamous Cell
 Brain Diseases Antibodies  >2 publications with NFIB and Brain Diseases
 Weight Loss Antibodies  >1 publications with NFIB and Weight Loss
 Cell Transformation, Neoplastic Antibodies  >1 publications with NFIB and Cell Transformation, Neoplastic

Organs/Tissues associated with NFIB cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >22 publications with NFIB and Brain
 Salivary Gland Antibodies  >21 publications with NFIB and Salivary Gland
 Lung Antibodies  >10 publications with NFIB and Lung
 Embryonic Tissue Antibodies  >8 publications with NFIB and Embryonic Tissue
 Bone Antibodies  >7 publications with NFIB and Bone
 Nerve Antibodies  >6 publications with NFIB and Nerve
 Muscle Antibodies  >4 publications with NFIB and Muscle
 Skin Antibodies  >4 publications with NFIB and Skin
 Mouth Antibodies  >3 publications with NFIB and Mouth
 Eye Antibodies  >3 publications with NFIB and Eye
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