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NFIC cDNA Clone – Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267235

MBS1267235 is a cDNA clone targeting NFIC. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NFIC, cDNA Clone
Full Product Name
NFIC cDNA Clone
Product Gene Name
NFIC cdna clone
Sequence
atgtattcgt ccccgctctg cctcacccag gatgagttcc acccgttcat cgaggccctg ctgcctcacg tccgcgcctt cgcctacacc tggttcaacc tgcaggcgcg gaagcgcaag tacttcaaga agcacgagaa gcggatgtcg aaggacgagg agcgtgcggt caaggacgag ctgctgggcg agaagcccga ggtcaagcag aagtgggcgt cgcggctgct ggccaagctg cgcaaggaca tccggcccga gtgccgcgag gacttcgtgc tgagcatcac cggcaagaag gcgccgggct gcgtgctctc caaccccgac cagaagggca agatgcggcg catcgactgt ctccggcagg cggacaaggt gtggcggctg gacctggtca tggtcatcct gttcaagggc atcccgctgg agagcaccga cggcgagcgc ctggtcaagg ctgcgcagtg cggtcacccg gtcctgtgcg tgcagccgca ccacattggc gtggccgtca aggagctgga cctctacctg gcctacttcg tgcgtgagcg agatgcagag caaagcggca gtccccggac agggatgggc tctgaccagg aggacagcaa gcccatcacg ctggacacga ccgacttcca ggagagcttt gtcacctccg gcgtgttcag cgtcactgag ctcatccaag tgtcccggac acccgtggtg actggaacag gacccaactt ctccctgggg gagctgcagg ggcacctggc atacgacctg aacccagcca gcactggcct cagaagaacg ctgcccagca cctcctccag tgggagcaag cggcacaaat cgggctcgat ggaggaagac gtggacacga gccctggcgg cgattactac acttcgccca gctcgcccac gagtagcagc cgcaactgga cggaggacat ggaaggaggc atctcgtccc cggtgaagaa gacagagatg gacaagtcac cattcaacag cccgtccccc caggactctc cccgcctctc cagcttcacc cagcaccacc ggcccgtcat cgccgtgcac agcgggatcg cccggagccc acacccgtcc tccgctctgc atttccctac gacgtccatc ctaccccaga cggcctccac ctacttcccc cacacggcca tccgctaccc acctcatctc aacccccagg acccgctcaa agatcttgtc tcgctggcct gcgacccagc cagccagcaa cctggaccgt cctggtatct gggatag
Molecular Weight
48,894 Da
OMIM
600729
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NFIC cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFIC. It may not necessarily be applicable to this product.

NCBI GI #
15082409
NCBI GeneID
4782
NCBI Accession #
BC012120
UniProt Secondary Accession #
P08652; Q14932; Q9UPJ3; Q9UPJ9; Q9UPK0; Q9UPK1; A8K1H0; B7Z4U5; B7Z9C3; K7EMU1
UniProt Related Accession #
P08651
NCBI Official Full Name
Homo sapiens nuclear factor I/C (CCAAT-binding transcription factor), mRNA
NCBI Official Synonym Full Names
nuclear factor I C
NCBI Official Symbol
NFIC
NCBI Official Synonym Symbols
CTF; NFI; CTF5; NF-I
UniProt Protein Name
Nuclear factor 1 C-type
UniProt Synonym Protein Names
CCAAT-box-binding transcription factor; CTF; Nuclear factor I/C; NF-I/C; NFI-C; TGGCA-binding protein
Protein Family
Nuclear factor
UniProt Gene Name
NFIC
UniProt Synonym Gene Names
NFI; NF1-C; Nuclear factor 1/C; CTF; NF-I/C; NFI-C
UniProt Entry Name
NFIC_HUMAN
NCBI Protein Information
nuclear factor 1 C-type

NCBI Summary for NFIC

The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for NFIC

NFI-C: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleolus; nucleus

Molecular Function: transcription factor activity

Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
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Research Articles on NFIC

1. Nuclear factor I-C regulates E-cadherin via control of KLF4 in breast cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NFIC cdna clone

 Products by Pathway  Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Termination Pathway antibodies  RNA Polymerase III Transcription Termination Pathway Diagram

Diseases associated with NFIC cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with NFIC and Neoplasms
 Nervous System Diseases Antibodies  >3 publications with NFIC and Nervous System Diseases
 Carcinoma Antibodies  >3 publications with NFIC and Carcinoma
 Brain Diseases Antibodies  >2 publications with NFIC and Brain Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with NFIC and Cell Transformation, Neoplastic
 Inflammation Antibodies  >2 publications with NFIC and Inflammation
 Cardiovascular Diseases Antibodies  >1 publications with NFIC and Cardiovascular Diseases
 Acute Kidney Injury Antibodies  >1 publications with NFIC and Acute Kidney Injury
 Adenocarcinoma Antibodies  >1 publications with NFIC and Adenocarcinoma
 Heart Diseases Antibodies  >1 publications with NFIC and Heart Diseases

Organs/Tissues associated with NFIC cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with NFIC and Brain
 Liver Antibodies  >14 publications with NFIC and Liver
 Mouth Antibodies  >8 publications with NFIC and Mouth
 Bone Antibodies  >7 publications with NFIC and Bone
 Lung Antibodies  >6 publications with NFIC and Lung
 Embryonic Tissue Antibodies  >5 publications with NFIC and Embryonic Tissue
 Kidney Antibodies  >4 publications with NFIC and Kidney
 Mammary Gland Antibodies  >3 publications with NFIC and Mammary Gland
 Spleen Antibodies  >3 publications with NFIC and Spleen
 Heart Antibodies  >3 publications with NFIC and Heart
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