Human NLGN4X cDNA Clone Expression Plasmid – Cat# MBS1271117

NLGN4X cDNA Clone – Neuroligin 4, X-Linked (Human)

Name: NLGN4X cDNA Clone; Neuroligin 4, X-Linked; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1271117
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1271117

MBS1271117 is a cDNA clone targeting NLGN4X. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NLGN4X, cDNA Clone

Full Product Name

NLGN4X cDNA Clone

Product Gene Name

NLGN4X cdna clone

Sequence

atgtcacggc cccagggact gctatggctt cctttgttgt tcaccccggt ctgcgtcatg ttaaactcca atgtcctcct gtggttaact gctcttgcca tcaagttcac cctcattgac agccaagcac agtatccagt tgtcaacaca aattatggca aaatccgggg cctaagaaca ccgttaccca atgagatctt gggtccagtg gagcagtact taggggtccc ctatgcctca ccccccactg gagagaggcg gtttcagccc ccagaacccc cgtcctcctg gactggcatc cgaaatacta ctcagtttgc tgctgtgtgc ccccagcacc tggatgagag atccttactg catgacatgc tgcccatctg gtttaccgcc aatttggata ctttgatgac ctatgttcaa gatcaaaatg aagactgcct ttacttaaac atctacgtgc ccacggaaga tgatattcat gatcagaaca gtaagaagcc cgtcatggtc tatatccatg ggggatctta catggagggc accggcaaca tgattgacgg cagcattttg gcaagctacg gaaacgtcat tgtgatcacc attaactacc gtctgggaat actagggttt ttaagtaccg gtgaccaggc agcaaaaggc aactatgggc tcctggatca gattcaagca ctgcggtgga ttgaggagaa tgtgggagcc tttggcgggg accccaagag agtgaccatc tttggctcgg gggctggggc ctcctgtgtc agcctgttga ccctgtccca ctactcagaa ggtctcttcc agaaggccat cattcagagc ggcaccgccc tgtccagctg ggcagtgaac taccagccgg ccaagtacac tcggatattg gcagacaagg tcggctgcaa catgctggac accacggaca tggtagaatg cctgcggaac aagaactaca aggagctcat ccagcagacc atcaccccgg ccacctacca catagccttc gggccggtga tcgacggcga cgtcatccca gacgaccccc agatcctgat ggagcaaggc gagttcctca actacgacat catgctgggc gtcaaccaag gggaaggcct gaagttcgtg gacggcatcg tggataacga ggacggtgtg acgcccaacg actttgactt ctccgtgtcc aacttcgtgg acaaccttta cggctaccct gaagggaaag acactttgcg ggagactatc aagttcatgt acacagactg ggccgataag gaaaacccgg agacgcggcg gaaaaccctg gtggctctct ttactgacca ccagtgggtg gcccccgccg tggccaccgc cgacctgcac gcgcagtacg gctcccccac ctacttctat gccttctatc atcactgcca aagcgaaatg aagcccagct gggcagattc ggcccatggt gatgaggtcc cctatgtctt cggcatcccc atgatcggtc ccaccgagct cttcagttgt aacttttcca agaacgacgt catgctcagc gccgtggtca tgacctactg gacgaacttc gccaaaactg gtgatccaaa tcaaccagtt cctcaggata ccaagttcat tcacacaaaa cccaaccgct ttgaagaagt ggcctggtcc aagtataatc ccaaagacca gctctatctg catattggct tgaaacccag agtgagagat cactaccggg caacgaaagt ggctttctgg ttggaactcg ttcctcattt gcacaacttg aacgagatat tccagtatgt ttcaacaacc acaaaggttc ctccaccaga catgacatca tttccctatg gcacccggcg atctcccgcc aagatatggc caaccaccaa acgcccagca atcactcctg ccaacaatcc caaacactct aaggaccctc acaaaacagg gcctgaggac acaactgtcc tcattgaaac caaacgagat tattccaccg aattaagtgt caccattgcc gtcggggcgt cgctcctctt cctcaacatc ttagcttttg cggcgctgta ctacaaaaag gacaagaggc gccatgagac tcacaggcgc cccagtcccc agagaaacac cacaaatgat atcgctcaca tccagaacga agagatcatg tctctgcaga tgaagcagct ggaacacgat cacgagtgtg agtcgctgca ggcacacgac acactgaggc tcacctgccc gccagactac accctcacgc tgcgccggtc gccagatgac atcccactta tgacgccaaa caccatcacc atgattccaa acacactgac ggggatgcag cctttgcaca cttttaacac cttcagtgga ggacaaaaca gtacaaattt accccacgga cattccacca ctagagtata g

Molecular Weight

94,047 Da

OMIM

300427

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NLGN4X cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NLGN4X. It may not necessarily be applicable to this product.

NCBI GI #

21706446

NCBI GeneID

57502

NCBI Accession #

BC034018

UniProt Secondary Accession #

Q6UX10; Q9ULG0

UniProt Related Accession #

Q8N0W4

NCBI Official Full Name

Homo sapiens neuroligin 4, X-linked, mRNA

NCBI Official Synonym Full Names

neuroligin 4, X-linked

NCBI Official Symbol

NLGN4X

NCBI Official Synonym Symbols

HLNX; HNL4X; NLGN4; ASPGX2; AUTSX2

UniProt Protein Name

Neuroligin-4, X-linked

UniProt Synonym Protein Names

HNLX

Protein Family

Neuroligin

UniProt Gene Name

NLGN4X

UniProt Synonym Gene Names

KIAA1260; NLGN4; Neuroligin X

UniProt Entry Name

NLGNX_HUMAN

NCBI Protein Information

neuroligin-4, X-linked

NCBI Summary for NLGN4X

This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

UniProt Comments for NLGN4X

NLGN4X: Putative neuronal cell surface protein involved in cell- cell-interactions. Defects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2). AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2). ASPGX2 is considered to be a form of childhood autism. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.33

Cellular Component: cell surface; dendrite; excitatory synapse; extracellular space; integral to plasma membrane; plasma membrane; synapse

Molecular Function: cell adhesion molecule binding; chloride ion binding; neurexin binding; protein binding; protein homodimerization activity; receptor activity

Biological Process: adult behavior; cerebellum development; learning; neuron adhesion; organ growth; social behavior; synapse organization and biogenesis

Disease: Asperger Syndrome, X-linked, Susceptibility To, 2; Autism, Susceptibility To, X-linked 2

Research Articles on NLGN4X

1. Endogenous NLGN4X is intensely phosphorylated on T707 upon PKC stimulation in human neurons.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NLGN4X cdna clone

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram

Diseases associated with NLGN4X cdna clone

Disease Name	Pubmed Publications
Child Development Disorders, Pervasive Antibodies	>33 publications with NLGN4X and Child Development Disorders, Pervasive
Autistic Disorder Antibodies	>32 publications with NLGN4X and Autistic Disorder
Disorders of Sex Development Antibodies	>2 publications with NLGN4X and Disorders of Sex Development
Gonadal Dysgenesis Antibodies	>1 publications with NLGN4X and Gonadal Dysgenesis

Organs/Tissues associated with NLGN4X cdna clone

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>26 publications with NLGN4X and Nerve
Brain Antibodies	>19 publications with NLGN4X and Brain
Muscle Antibodies	>3 publications with NLGN4X and Muscle
Blood Antibodies	>2 publications with NLGN4X and Blood
Pancreas Antibodies	>2 publications with NLGN4X and Pancreas
Embryonic Tissue Antibodies	>2 publications with NLGN4X and Embryonic Tissue
Heart Antibodies	>1 publications with NLGN4X and Heart
Liver Antibodies	>1 publications with NLGN4X and Liver