Human NPR3 cDNA Clone Expression Plasmid – Cat# MBS1272108

NPR3 cDNA Clone – Natriuretic Peptide Receptor C/Guanylate Cyclase C (Atrionatriuretic Peptide Receptor C) (Human)

Name: NPR3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272108
Price: 635 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272108

MBS1272108 is a cDNA clone targeting NPR3. More details

$635 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NPR3, cDNA Clone

Full Product Name

NPR3 cDNA Clone

Product Gene Name

NPR3 cdna clone

Sequence

ATGCCGTCTC TGCTGGTGCT CACTTTCTCC CCGTGCGTAC TACTCGGCTG GGCGTTGCTG GCCGGCGGCA CCGGTGGCGG TGGCGTTGGC GGCGGCGGCG GTGGCGCGGG CATAGGCGGC GGACGCCAGG AGAGAGAGGC GCTGCCGCCA CAGAAGATCG AGGTGCTGGT GTTACTGCCC CAGGATGACT CGTACTTGTT TTCACTCACC CGGGTGCGGC CGGCCATCGA GTATGCTCTG CGCAGCGTGG AGGGCAACGG GACTGGGAGG CGGCTTCTGC CGCCGGGCAC TCGCTTCCAG GTGGCTTACG AGGATTCAGA CTGTGGGAAC CGTGCGCTCT TCAGCTTGGT GGACCGCGTG GCGGCGGCGC GGGGCGCCAA GCCAGACCTT ATCCTGGGGC CAGTGTGCGA GTATGCAGCA GCGCCAGTGG CCCGGCTTGC ATCGCACTGG GACCTGCCCA TGCTGTCGGC TGGGGCGCTG GCCGCTGGCT TCCAGCACAA GGACTCTGAG TACTCGCACC TCACGCGCGT GGCGCCCGCC TACGCCAAGA TGGGCGAGAT GATGCTCGCC CTGTTCCGCC ACCACCACTG GAGCCGCGCT GCACTGGTCT ACAGCGACGA CAAGCTGGAG CGGAACTGCT ACTTCACCCT CGAGGGGGTC CACGAGGTCT TCCAGGAGGA GGGTTTGCAC ACGTCCATCT ACAGTTTCGA CGAGACCAAA GACTTGGATC TGGAAGACAT CGTGCGCAAT ATCCAGGCCA GTGAGAGAGT GGTGATCATG TGTGCGAGCA GTGACACCAT CCGGAGCATC ATGCTGGTGG CGCACAGGCA TGGCATGACC AGTGGAGACT ACGCCTTCTT CAACATTGAG CTCTTCAACA GCTCTTCCTA TGGAGATGGC TCATGGAAGA GAGGAGACAA ACACGACTTT GAAGCTAAGC AAGCATACTC GTCCCTCCAG ACAGTCACTC TACTGAGGAC AGTGAAACCT GAGTTTGAGA AGTTTTCCAT GGAGGTGAAA AGTTCAGTTG AGAAACAAGG GCTCAATATG GAGGATTACG TTAACATGTT TGTTGAAGGA TTCCACGATG CCATCCTCCT CTACGTCTTG GCTCTACATG AAGTACTCAG AGCTGGTTAC AGCAAAAAGG ATGGAGGGAA AATTATACAG CAGACTTGGA ACAGAACATT TGAAGGTATC GCCGGGCAGG TGTCCATAGA TGCCAACGGA GACCGATATG GGGATTTCTC TGTGATTGCC ATGACTGATG TGGAGGCGGG CACCCAGGAG GTTATTGGTG ATTATTTTGG AAAAGAAGGT CGTTTTGAAA TGCGGCCGAA TGTCAAATAT CCTTGGGGCC CTTTAAAACT GAGAATAGAT GAAAACCGAA TTGTAGAGCA TACAAACAGC TCTCCCTGCA AATCATCAGG TGGCCTAGAA GAATCGGCAG TGACAGGAAT TGTCGTGGGG GCTTTACTAG GAGCTGGCTT GCTAATGGCC TTCTACTTTT TCAGGAAGAA ATACAGAATA ACCATTGAGA GGCGAACCCA GCAAGAAGAA AGTAACCTTG GAAAACATCG GGAATTACGG GAAGATTCCA TCAGATCCCA TTTTTCAGTA GCTTAA

Molecular Weight

36,656 Da

OMIM

108962

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NPR3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NPR3. It may not necessarily be applicable to this product.

NCBI GI #

124297950

NCBI GeneID

4883

NCBI Accession #

BC131540

UniProt Secondary Accession #

A2RRD1; B4DT84; E7EPG9

UniProt Related Accession #

P17342

NCBI Official Full Name

Homo sapiens natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), mRNA

NCBI Official Synonym Full Names

natriuretic peptide receptor 3

NCBI Official Symbol

NPR3

NCBI Official Synonym Symbols

NPRC; ANP-C; ANPRC; NPR-C; ANPR-C; GUCY2B; C5orf23

UniProt Protein Name

Atrial natriuretic peptide receptor 3

UniProt Synonym Protein Names

Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor type C; ANP-C; ANPR-C; NPR-C

Protein Family

Atrial natriuretic peptide receptor

UniProt Gene Name

NPR3

UniProt Synonym Gene Names

ANPRC; C5orf23; NPRC; ANP-C; ANPR-C; NPR-C

UniProt Entry Name

ANPRC_HUMAN

NCBI Protein Information

atrial natriuretic peptide receptor 3

NCBI Summary for NPR3

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

UniProt Comments for NPR3

ANP-C: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. Belongs to the ANF receptor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: adenylate cyclase activity; hormone binding; natriuretic peptide receptor activity; peptide hormone binding; peptide receptor activity, G-protein coupled

Biological Process: cAMP biosynthetic process; cAMP-mediated signaling; cyclic nucleotide biosynthetic process; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of nitric-oxide synthase activity; regulation of blood pressure; regulation of osteoblast proliferation; skeletal development

Research Articles on NPR3

1. This study focused on the natriuretic peptide receptor C gene (NPR3). The correlation analysis between NPR3 and hypertension was replicated in 450 Chinese Dai and 484 Chinese Mongolian individuals.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with NPR3 cdna clone

Disease Name	Pubmed Publications
Hypertension Antibodies	>9 publications with NPR3 and Hypertension
Brain Diseases Antibodies	>6 publications with NPR3 and Brain Diseases
Neoplasms Antibodies	>3 publications with NPR3 and Neoplasms
Congenital Abnormalities Antibodies	>2 publications with NPR3 and Congenital Abnormalities
Insulin Resistance Antibodies	>1 publications with NPR3 and Insulin Resistance
Proteinuria Antibodies	>1 publications with NPR3 and Proteinuria
Lung Diseases Antibodies	>1 publications with NPR3 and Lung Diseases
Drug Toxicity Antibodies	>1 publications with NPR3 and Drug Toxicity
Hypertrophy Antibodies	>1 publications with NPR3 and Hypertrophy
Learning Disorders Antibodies	>1 publications with NPR3 and Learning Disorders

Organs/Tissues associated with NPR3 cdna clone

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>3 publications with NPR3 and Connective Tissue