Human NRCAM cDNA Clone Expression Plasmid – Cat# MBS1272449

NRCAM cDNA Clone – Neuronal Cell Adhesion Molecule (Human)

Name: NRCAM cDNA Clone; Neuronal Cell Adhesion Molecule; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272449
Price: 1490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272449

MBS1272449 is a cDNA clone targeting NRCAM. More details

$1490 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NRCAM, cDNA Clone

Full Product Name

NRCAM cDNA Clone

Product Gene Name

NRCAM cdna clone

Sequence

ATGCAGCTTA AAATAATGCC GAAAAAGAAG CGCTTATCTG CGGGCAGAGT GCCCCTGATT CTCTTCCTGT GCCAGATGAT TAGTGCACTG GAAGTACCTC TTGATCCAAA ACTTCTTGAA GACTTGGTAC AGCCTCCAAC CATCACCCAA CAGTCTCCAA AAGATTACAT TATTGACCCT CGGGAGAATA TTGTAATCCA GTGTGAAGCC AAAGGGAAAC CGCCCCCAAG CTTTTCCTGG ACCCGTAATG GGACTCATTT TGACATCGAT AAAGACCCTC TGGTCACCAT GAAGCCTGGC ACAGGAACGC TCATAATTAA CATCATGAGC GAAGGGAAAG CTGAGACCTA TGAAGGAGTC TATCAGTGTA CAGCAAGGAA CGAACGCGGA GCTGCAGTTT CTAATAACAT TGTTGTCCGC CCATCCAGAT CACCATTGTG GACCAAAGAA AAACTTGAAC CAATCACACT TCAAAGTGGT CAGTCTTTAG TACTTCCCTG CAGACCCCCA ATTGGATTAC CACCACCTAT AATATTTTGG ATGGATAATT CCTTTCAAAG ACTTCCACAA AGTGAGAGAG TTTCTCAAGG TTTGAATGGG GACCTTTATT TTTCCAATGT CCTCCCAGAG GACACCCGCG AAGACTATAT CTGTTATGCT AGATTTAATC ATACTCAAAC CATACAGCAG AAGCAACCTA TTTCTGTGAA GGTGATTTCA GCTAAATCAA GTAGAGAGAG GCCACCAACA TTTTTAACTC CAGAAGGCAA TGCAAGTAAC AAAGAGGAAT TAAGAGGAAA TGTGCTTTCA CTGGAGTGCA TTGCAGAAGG ACTGCCTACC CCAATTATTT ACTGGGCAAA GGAAGATGGA ATGCTACCCA AAAACAGGAC AGTTTATAAG AACTTTGAGA AAACCTTGCA GATCATTCAT GTTTCAGAAG CAGACTCTGG AAATTACCAA TGTATAGCAA AAAATGCATT AGGAGCCATC CACCATACCA TTTCTGTTAG AGTTAAAGCG GCTCCATACT GGATCACAGC CCCTCAAAAT CTTGTGCTGT CCCCAGGAGA GGATGGGACC TTGATCTGCA GAGCTAATGG CAACCCCAAA CCCAGAATTA GCTGGTTAAC AAATGGAGTC CCAATAGAAA TTGCCCCTGA TGACCCCAGC AGAAAAATAG ATGGCGATAC CATTATTTTT TCAAATGTTC AAGAAAGATC AAGTGCAGTA TATCAGTGCA ATGCCTCTAA TGAATATGGA TATTTACTGG CAAACGCATT TGTAAATGTG CTGGCTGAGC CACCACGAAT CCTCACACCT GCAAACACAC TCTACCAGGT CATTGCAAAC AGGCCTGCTT TACTAGACTG TGCCTTCTTT GGGTCTCCTC TCCCAACCAT CGAGTGGTTT AAAGGAGCTA AAGGAAGTGC TCTTCATGAA GATATTTATG TTTTACATGA AAATGGAACT TTGGAAATTC CTGTGGCCCA AAAGGACAGT ACAGGAACTT ATACGTGTGT TGCAAGGAAT AAATTAGGGA TGGCAAAGAA TGAAGTTCAC TTAGAAATCA AAGATGCTAC ATGGATCGTT AAACAGCCCG AATATGCAGT TGTGCAAAGA GGGAGCATGG TGTCCTTTGA ATGCAAAGTG AAACATGATC ACACCTTATC CCTCACTGTC CTGTGGCTGA AGGACAACAG GGAACTGCCC AGTGATGAAA GGTTCACTGT TGACAAGGAT CATCTAGTGG TAGCTGATGT CAGTGACGAT GACAGCGGGA CCTACACGTG TGTGGCCAAC ACCACTCTGG ACAGCGTCTC CGCCAGCGCT GTGCTTAGCG TTGTTGCTCC TACTCCAACT CCAGCTCCCG TTTACGATGT CCCAAATCCT CCCTTTGACT TAGAACTGAC AGATCAACTT GACAAAAGTG TTCAGCTGTC ATGGACCCCA GGCGATGACA ACAATAGCCC CATTACAAAA TTCATCATCG AATATGAAGA TGCAATGCAC AAGCCAGGGC TGTGGCACCA CCAAACTGAA GTTTCTGGAA CACAGACCAC AGCCCAGCTG AAGCTGTCTC CTTACGTGAA CTACTCCTTC CGCGTGATGG CAGTGAACAG CATTGGGAAG AGCTTGCCCA GCGAGGCCTC TGAGCAGTAT TTGACGAAAG CCTCAGAACC AGATAAAAAC CCCACAGCTG TGGAAGGACT GGGATCAGAG CCTGATAATT TGGTGATTAC GTGGAAGCCC TTGAATGGTT TCGAATCTAA TGGGCCAGGC CTTCAGTACA AAGTTAGCTG GCGCCAGAAA GATGGTGATG ATGAATGGAC ATCTGTGGTT GTGGCAAATG TATCCAAATA TATTGTCTCA GGCACGCCAA CCTTTGTTCC ATACCTGATC AAAGTTCAGG CCCTGAATGA CATGGGGTTT GCCCCCGAGC CAGCTGTAGT CATGGGACAT TCTGGAGAAG ACCTCCCAAT GGTGGCTCCT GGGAACGTGC GTGTGAATGT GGTGAACAGT ACCTTAGCCG AGGTGCACTG GGACCCAGTA CCTCTGAAAA GCATCCGAGG ACACCTACAA GGCTATCGGA TTTACTATTG GAAGACCCAG AGTTCATCTA AAAGAAACAG ACGTCACATT GAGAAAAAGA TCCTCACCTT CCAAGGCAGC AAGACTCATG GCATGTTGCC GGGGCTAGAG CCCTTTAGCC ACTACACACT GAATGTCCGA GTGGTCAATG GGAAAGGGGA GGGCCCAGCC AGCCCTGACA GAGTCTTTAA TACTCCAGAA GGAGTCCCCA GTGCTCCCTC GTCTTTGAAG ATTGTGAATC CAACACTGGA CTCTCTCACT TTGGAATGGG ATCCACCGAG CCACCCGAAT GGCATTTTGA CAGAGTACAC CTTAAAGTAT CAGCCAATTA ACAGCACACA TGAATTAGGC CCTCTGGTAG ATTTGAAAAT TCCTGCCAAC AAGACACGGT GGACTTTAAA AAATTTAAAT TTCAGCACTC GATATAAGTT TTATTTCTAT GCACAAACAT CAGCAGGATC AGGAAGTCAA ATTACAGAGG AAGCAGTAAC AACTGTGGAT GAAGCTGGTA TTCTTCCACC TGATGTAGGT GCAGGCAAAG CGATGGCAAG CCGGCAGGTG GATATTGCAA CTCAGGGCTG GTTCATTGGT CTGATGTGTG CTGTTGCTCT CCTTATCTTA ATTTTGCTGA TTGTTTGCTT CATCAGAAGA AACAAGGGTG GTAAATATCC AGTTAAAGAA AAGGAAGATG CCCATGCTGA CCCTGAAATC CAGCCTATGA AGGAAGATGA TGGGACATTT GGAGAATACA GTGATGCAGA AGACCACAAG CCTTTGAAAA AAGGAAGTCG AACTCCTTCA GACAGGACTG TGAAAAAAGA AGATAGTGAC GACAGCCTAG TTGACTATGG AGAAGGGGTT AATGGCCAGT TCAATGAGGA TGGCTCCTTT ATTGGACAAT ACAGTGGTAA GAAAGAGAAA GAGCCGGCTG AAGGAAACGA AAGCTCAGAG GCACCTTCTC CTGTCAACGC CATGAATTCC TTTGTTTAA

Molecular Weight

131,744 Da

OMIM

601581

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NRCAM cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NRCAM. It may not necessarily be applicable to this product.

NCBI GI #

109730332

NCBI GeneID

4897

NCBI Accession #

BC115736

UniProt Secondary Accession #

O15051; O15179; Q14BM2; Q9UHI3; Q9UHI4; A4D0S3; E9PDA4

UniProt Related Accession #

Q92823

NCBI Official Full Name

Homo sapiens neuronal cell adhesion molecule, mRNA

NCBI Official Synonym Full Names

neuronal cell adhesion molecule

NCBI Official Symbol

NRCAM

UniProt Protein Name

Neuronal cell adhesion molecule

UniProt Synonym Protein Names

Neuronal surface protein Bravo

Protein Family

Neuronal cell adhesion molecule

UniProt Gene Name

NRCAM

UniProt Synonym Gene Names

KIAA0343; Ng-CAM-related

UniProt Entry Name

NRCAM_HUMAN

NCBI Protein Information

neuronal cell adhesion molecule

NCBI Summary for NRCAM

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for NRCAM

NRCAM: Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier. Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: plasma membrane

Molecular Function: ankyrin binding; protein binding

Biological Process: angiogenesis; clustering of voltage-gated sodium channels; synaptogenesis

Research Articles on NRCAM

1. A high level of Nr-CAM expression is associated with favorable tumor phenotype and reduced risk of prostate cancer recurrence.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NRCAM cdna clone

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Interaction Between L1 And Ankyrins Pathway antibodies	Interaction Between L1 And Ankyrins Pathway Diagram
L1CAM Interactions Pathway antibodies	L1CAM Interactions Pathway Diagram
Neurofascin Interactions Pathway antibodies	Neurofascin Interactions Pathway Diagram
NrCAM Interactions Pathway antibodies	NrCAM Interactions Pathway Diagram

Diseases associated with NRCAM cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>33 publications with NRCAM and Neoplasms
Brain Diseases Antibodies	>11 publications with NRCAM and Brain Diseases
Autistic Disorder Antibodies	>6 publications with NRCAM and Autistic Disorder
Inflammation Antibodies	>3 publications with NRCAM and Inflammation
Cell Transformation, Neoplastic Antibodies	>3 publications with NRCAM and Cell Transformation, Neoplastic
Substance-Related Disorders Antibodies	>3 publications with NRCAM and Substance-Related Disorders
Breast Neoplasms Antibodies	>3 publications with NRCAM and Breast Neoplasms
Hyperplasia Antibodies	>2 publications with NRCAM and Hyperplasia
Colorectal Neoplasms Antibodies	>2 publications with NRCAM and Colorectal Neoplasms
Skin Neoplasms Antibodies	>2 publications with NRCAM and Skin Neoplasms

Organs/Tissues associated with NRCAM cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>58 publications with NRCAM and Brain
Nerve Antibodies	>49 publications with NRCAM and Nerve
Eye Antibodies	>14 publications with NRCAM and Eye
Embryonic Tissue Antibodies	>13 publications with NRCAM and Embryonic Tissue
Blood Antibodies	>11 publications with NRCAM and Blood
Vascular Antibodies	>6 publications with NRCAM and Vascular
Muscle Antibodies	>5 publications with NRCAM and Muscle
Liver Antibodies	>4 publications with NRCAM and Liver
Kidney Antibodies	>4 publications with NRCAM and Kidney
Heart Antibodies	>3 publications with NRCAM and Heart