Human P2RX2 cDNA Clone Expression Plasmid – Cat# MBS1268771

P2RX2 cDNA Clone – Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2 (Human)

Name: P2RX2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1268771
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1268771

MBS1268771 is a cDNA clone targeting P2RX2. More details

$430 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

P2RX2, cDNA Clone

Full Product Name

P2RX2 cDNA Clone

Product Gene Name

P2RX2 cdna clone

Sequence

ATGGCCGCCG CCCAGCCCAA GTACCCCGCC GGGGCGACCG CCCGGCGCCT GGCCCGGGGC TGCTGGTCCG CCCTCTGGGA CTACGAGACG CCCAAGGTGA TCGTGGTGAG GAACCGGCGC CTGGGGGTCC TGTACCGCGC CGTGCAGCTG CTCATCCTGC TCTACTTCGT GTGGTACGTA TTCATCGTGC AGAAAAGCTA CCAGGAGAGC GAGACGGGCC CCGAGAGCTC CATCATCACC AAGGTCAAGG GGATCACCAC GTCCGAGCAC AAAGTGTGGG ACGTGGAGGA GTACGTGAAG CCCCCCGAGG GGGGCAGCGT GTTCAGCATC ATCACCAGGG TCGAGGCCAC CCACTCCCAG ACCCAGGGAA CCTGCCCCGA GAGCATAAGG GTCCACAACG CCACCTGCCT CTCCGACGCC GACTGCGTGG CTGGGGAGCT GGACATGCTG GGAAACGGCC TGAGGACTGG GCGCTGTGTG CCCTATTACC AGGGGCCCTC CAAGACCTGC GAGGTGTTCG GCTGGTGCCC GGTGGAAGAT GGGGCCTCTG TCAGCCAATT TCTGGGTACG ATGGCCCCAA ATTTCACCAT CCTCATCAAG AACAGCATCC ACTACCCCAA ATTCCACTTC TCCAAGGGCA ACATCGCCGA CCGCACAGAC GGGTACCTGA AGCGCTGCAC GTTCCACGAG GCCTCCGACC TCTACTGCCC CATCTTCAAG CTGGGCTTTA TCGTGGAGAA GGCTGGGGAG AGCTTCACAG AGCTCGCACA CAAGGGTGGT GTCATCGGGG TCATTATCAA CTGGGACTGT GACCTGGACC TGCCTGCATC GGAGTGCAAC CCCAAGTACT CCTTCCGGAG GCTTGACCCC AAGCACGTGC CTGCCTCGTC AGGCTACAAC TTCAGGTTTG CCAAATACTA CAAGATCAAT GGCACCACCA CCCGCACGCT CATCAAGGCC TACGGGATCC GCATTGACGT CATTGTGCAT GGACAGGTGC CTGCACCTGC TGGGGGCCGG GAAGTTCAGC CTGATTCCCA CCATTATTAA

Molecular Weight

41,370 Da

OMIM

600844

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of P2RX2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RX2. It may not necessarily be applicable to this product.

NCBI GI #

115344415

NCBI GeneID

22953

NCBI Accession #

BC109200

UniProt Secondary Accession #

Q6V9R6; Q9NR37; Q9NR38; Q9UHD5; Q9UHD6; Q9UHD7; A6NGB4; A6NH93; A6NHC2; A6NHU3; A6NIG9

UniProt Related Accession #

Q9UBL9

NCBI Official Full Name

Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 2, mRNA

NCBI Official Synonym Full Names

purinergic receptor P2X 2

NCBI Official Symbol

P2RX2

NCBI Official Synonym Symbols

P2X2; DFNA41

UniProt Protein Name

P2X purinoceptor 2

UniProt Synonym Protein Names

ATP receptor; Purinergic receptor

Protein Family

P2X purinoceptor

UniProt Gene Name

P2RX2

UniProt Synonym Gene Names

P2X2; P2X2

UniProt Entry Name

P2RX2_HUMAN

NCBI Protein Information

P2X purinoceptor 2

NCBI Summary for P2RX2

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]

UniProt Comments for P2RX2

P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Channel, cation; Membrane protein, integral; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: apical plasma membrane; integral to nuclear inner membrane; integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: ATP-gated cation channel activity; identical protein binding; ligand-gated ion channel activity; purinergic nucleotide receptor activity

Biological Process: blood coagulation; protein homooligomerization; sensory perception of sound

Disease: Deafness, Autosomal Dominant 41

Research Articles on P2RX2

1. Results demonstrate that the stoichiometry of the heterotrimeric hP2X2/3 receptor is not fixed, but determined by the relative availability of P2X2 and P2X3 subunits

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with P2RX2 cdna clone

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with P2RX2 cdna clone

Disease Name	Pubmed Publications
Pain Antibodies	>91 publications with P2RX2 and Pain
Nervous System Diseases Antibodies	>67 publications with P2RX2 and Nervous System Diseases
Inflammation Antibodies	>28 publications with P2RX2 and Inflammation
Hyperalgesia Antibodies	>24 publications with P2RX2 and Hyperalgesia
Disease Models, Animal Antibodies	>19 publications with P2RX2 and Disease Models, Animal
Neoplasms Antibodies	>15 publications with P2RX2 and Neoplasms
Brain Diseases Antibodies	>7 publications with P2RX2 and Brain Diseases
Cardiovascular Diseases Antibodies	>5 publications with P2RX2 and Cardiovascular Diseases
Kidney Diseases Antibodies	>4 publications with P2RX2 and Kidney Diseases
Nerve Degeneration Antibodies	>3 publications with P2RX2 and Nerve Degeneration