Human PAK6 cDNA Clone Expression Plasmid – Cat# MBS1269516

PAK6 cDNA Clone – P21 Protein (Cdc42/Rac)-Activated Kinase 6 (Human)

Name: PAK6 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269516
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269516

MBS1269516 is a cDNA clone targeting PAK6. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PAK6, cDNA Clone

Full Product Name

PAK6 cDNA Clone

Product Gene Name

PAK6 cdna clone

Sequence

atgttccgca agaaaaagaa gaaacgccct gagatctcag cgccacagaa cttccagcac cgtgtccaca cctccttcga ccccaaagaa ggcaagtttg tgggcctccc cccacaatgg cagaacatcc tggacacact gcggcgcccc aagcccgtgg tggacccttc gcgaatcaca cgggtgcagc tccagcccat gaagacagtg gtgcggggca gcgcgatgcc tgtggatggc tacatctcgg ggctgctcaa cgacatccag aagttgtcag tcatcagctc caacaccctg cgtggccgca gccccaccag ccggcggcgg gcacagtccc tggggctgct gggggatgag cactgggcca ccgacccaga catgtacctc cagagccccc agtctgagcg cactgacccc cacggcctct acctcagctg caacgggggc acaccagcag gccacaagca gatgccgtgg cccgagccac agagcccacg ggtcctgccc aatgggctgg ctgcaaaggc acagtccctg ggccccgccg agtttcaggg tgcctcgcag cgctgtctgc agctgggtgc ctgcctgcag agctccccac caggagcctc gccccccacg ggcaccaata ggcatggaat gaaggctgcc aagcatggct ctgaggaggc ccggccacag tcctgcctgg tgggctcagc cacaggcagg ccaggtgggg aaggcagccc tagccctaag acccgggaga gcagcctgaa gcgcaggcta ttccgaagca tgttcctgtc cactgctgcc acagcccctc caagcagcag caagccaggc cctccaccac agagcaagcc caactcctct ttccgaccgc cgcagaaaga caacccccca agcctggtgg ccaaggccca gtccttgccc tcggaccagc cggtggggac cttcagccct ctgaccactt cggataccag cagcccccag aagtccctcc gcacagcccc ggccacaggc cagcttccag gccggtcttc cccagcggga tccccccgca cctggcacgc ccagatcagc accagcaacc tgtacctgcc ccaggacccc acggttgcca agggtgccct ggctggtgag gacacaggtg ttgtgacaca tgagcagttc aaggctgcgc tcaggatggt ggtggaccag ggtgaccccc ggctgctgct ggacagctac gtgaagattg gcgagggctc caccggcatc gtctgcttgg cccgggagaa gcactcgggc cgccaggtgg ccgtcaagat gatggacctc aggaagcagc agcgcaggga gctgctcttc aacgaggtgg tgatcatgcg ggactaccag cacttcaacg tggtggagat gtacaagagc tacctggtgg gcgaggagct gtgggtgctc atggagttcc tgcagggagg agccctcaca gacatcgtct cccaagtcag gctgaatgag gagcagattg ccactgtgtg tgaggctgtg ctgcaggccc tggcctacct gcatgctcag ggtgtcatcc accgggacat caagagtgac tccatcctgc tgaccctcga tggcagggtg aagctctcgg acttcggatt ctgtgctcag atcagcaaag acgtccctaa gaggaagtcc ctggtgggaa ccccctactg gatggctcct gaagtgatct ccaggtcttt gtatgccact gaggtggata tctggtctct gggcatcatg gtgattgaga tggtagatgg ggagccaccg tacttcagtg actccccagt gcaagccatg aagaggctcc gggacagccc cccacccaag ctgaaaaact ctcacaaggt ctccccagtg ctgcgagact tcctggagcg gatgctggtg cgggaccccc aagagagagc cacagcccag gagctcctag accacccctt cctgctgcag acagggctac ctgagtgcct ggtgcccctg atccagctct accgaaagca gacctccacc tgctga

Molecular Weight

69,777 Da

OMIM

608110

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PAK6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PAK6. It may not necessarily be applicable to this product.

NCBI GI #

23272545

NCBI GeneID

56924

NCBI Accession #

BC035596

UniProt Secondary Accession #

A8K2G2; B3KYB0; G5E9R2

UniProt Related Accession #

Q9NQU5

NCBI Official Full Name

Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 6, mRNA

NCBI Official Synonym Full Names

p21 (RAC1) activated kinase 6

NCBI Official Symbol

PAK6

NCBI Official Synonym Symbols

PAK5

UniProt Protein Name

Serine/threonine-protein kinase PAK 6

UniProt Synonym Protein Names

PAK-5; p21-activated kinase 6; PAK-6

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

PAK6

UniProt Synonym Gene Names

PAK5; PAK-6

UniProt Entry Name

PAK6_HUMAN

NCBI Protein Information

serine/threonine-protein kinase PAK 6

NCBI Summary for PAK6

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

UniProt Comments for PAK6

PAK6: a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues.

Protein type: EC 2.7.11.1; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Nuclear receptor co-regulator; Kinase, protein; STE group; STE20 family; PAKB subfamily

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: cell-cell adherens junction; cytoplasm

Molecular Function: protein binding; receptor signaling protein serine/threonine kinase activity

Biological Process: apoptosis; cytoskeleton organization and biogenesis; mitotic cell cycle; regulation of transcription, DNA-dependent

Research Articles on PAK6

1. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2), a kinase involved in Parkinson's disease

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PAK6 cdna clone

Products by Pathway	Pathway Diagram
Activation Of Rac Pathway antibodies	Activation Of Rac Pathway Diagram
Androgen Receptor Signaling Pathway antibodies	Androgen Receptor Signaling Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram

Diseases associated with PAK6 cdna clone

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>9 publications with PAK6 and Prostatic Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with PAK6 and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>2 publications with PAK6 and Cell Transformation, Neoplastic
Memory Disorders Antibodies	>1 publications with PAK6 and Memory Disorders
Cognition Disorders Antibodies	>1 publications with PAK6 and Cognition Disorders
Neurobehavioral Manifestations Antibodies	>1 publications with PAK6 and Neurobehavioral Manifestations
Learning Disorders Antibodies	>1 publications with PAK6 and Learning Disorders
Inflammation Antibodies	>1 publications with PAK6 and Inflammation
Necrosis Antibodies	>1 publications with PAK6 and Necrosis

Organs/Tissues associated with PAK6 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with PAK6 and Brain
Testis Antibodies	>2 publications with PAK6 and Testis
Kidney Antibodies	>1 publications with PAK6 and Kidney
Bone Antibodies	>1 publications with PAK6 and Bone
Blood Antibodies	>1 publications with PAK6 and Blood
Cervix Antibodies	>1 publications with PAK6 and Cervix
Skin Antibodies	>1 publications with PAK6 and Skin
Bone Marrow Antibodies	>1 publications with PAK6 and Bone Marrow
Embryonic Tissue Antibodies	>1 publications with PAK6 and Embryonic Tissue