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PDIA6 cDNA Clone – Protein Disulfide Isomerase Family A, Member 6 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278686

MBS1278686 is a cDNA clone targeting PDIA6. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDIA6, cDNA Clone
Full Product Name
PDIA6 cDNA Clone
Product Gene Name
PDIA6 cdna clone
Sequence
atggctctcc tggtgctcgg tctggtgagc tgtaccttct ttctggcagt gaatggtctg tattcctcta gtgatgatgt gatcgaatta actccatcga atttcaaccg agaagttatt cagagtgata gtttgtggct tgtagaattc tatgctccat ggtgtggtca ctgtcaaaga ttaacaccag aatggaagaa agcagcaact gcattaaaag atgttgtcaa agttggtgca gttgatgcag ataagcatca ttccctagga ggtcagtatg gtgttcaggg atttcctacc attaagattt ttggatccaa caaaaacaga ccagaagatt accaaggtgg cagaactggt gaagccattg tagatgctgc gctgagtgct ctgcgccagc tcgtgaagga tcgcctcggg ggacggagcg gaggatacag ttctggaaaa caaggcagaa gtgatagttc aagtaagaag gatgtgattg agctgacaga cgacagcttt gataagaatg ttctggacag tgaagatgtt tggatggttg agttctatgc tccttggtgt ggacactgca aaaacctaga gccagagtgg gctgccgcag cttcagaagt aaaagagcag acgaaaggaa aagtgaaact ggcagctgtg gatgctacag tcaatcaggt tctggcctcc cgatacggga ttagaggatt tcctacaatc aagatatttc agaaaggcga gtctcctgtg gattatgacg gtgggcggac aagatccgac atcgtgtccc gggcccttga tttgttttct gataacgccc cacctcctga gctgcttgag attatcaacg aggacattgc caagaggacg tgtgaggagc accagctctg tgttgtggct gtgctgcccc atatccttga tactggagct gcaggcagaa attcttatct ggaagttctt ctgaagttgg cagacaaata caaaaagaaa atgtgggggt ggctgtggac agaagctgga gcccagtctg aacttgagac cgcgttgggg attggagggt ttgggtaccc cgccatggcc gccatcaatg cacgcaagat gaaatttgct ctgctaaaag gctccttcag tgagcaaggc atcaacgagt ttctcaggga gctctctttt gggcgtggct ccacggcacc tgtaggaggc ggggctttcc ctaccatcgt tgagagagag ccttgggacg gcagggatgg cgagcttccc gtggaggatg acattgacct cagtgatgtg gagcttgatg acttagggaa agatgagttg tga
Molecular Weight
53,261 Da
OMIM
611099
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PDIA6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDIA6. It may not necessarily be applicable to this product.

NCBI GI #
12654930
NCBI GeneID
10130
NCBI Accession #
BC001312
UniProt Secondary Accession #
Q53RC7; Q6ZSH5; Q99778; B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83
UniProt Related Accession #
Q15084
NCBI Official Full Name
Homo sapiens protein disulfide isomerase family A, member 6, mRNA
NCBI Official Synonym Full Names
protein disulfide isomerase family A member 6
NCBI Official Symbol
PDIA6
NCBI Official Synonym Symbols
P5; ERP5; TXNDC7
UniProt Protein Name
Protein disulfide-isomerase A6
UniProt Synonym Protein Names
Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7
Protein Family
Protein disulfide-isomerase
UniProt Gene Name
PDIA6
UniProt Synonym Gene Names
ERP5; P5; TXNDC7; ER protein 5; ERp5
UniProt Entry Name
PDIA6_HUMAN
NCBI Protein Information
protein disulfide-isomerase A6

NCBI Summary for PDIA6

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM, Mar 2008]
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UniProt Comments for PDIA6

PDIA6: May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. Belongs to the protein disulfide isomerase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.3.4.1; Isomerase

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; ER-Golgi intermediate compartment

Molecular Function: protein binding

Biological Process: apoptotic cell clearance; protein folding
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Research Articles on PDIA6

1. Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PDIA6 cdna clone

 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Unfolded Protein Response Pathway antibodies  Unfolded Protein Response Pathway Diagram

Diseases associated with PDIA6 cdna clone

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >3 publications with PDIA6 and Immune System Diseases
 Nervous System Diseases Antibodies  >2 publications with PDIA6 and Nervous System Diseases
 Kidney Diseases Antibodies  >2 publications with PDIA6 and Kidney Diseases
 Disease Models, Animal Antibodies  >1 publications with PDIA6 and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with PDIA6 and Brain Diseases
 Liver Diseases Antibodies  >1 publications with PDIA6 and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with PDIA6 and Cardiovascular Diseases
 Inflammation Antibodies  >1 publications with PDIA6 and Inflammation

Organs/Tissues associated with PDIA6 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with PDIA6 and Blood
 Brain Antibodies  >3 publications with PDIA6 and Brain
 Bone Antibodies  >2 publications with PDIA6 and Bone
 Kidney Antibodies  >2 publications with PDIA6 and Kidney
 Pancreas Antibodies  >2 publications with PDIA6 and Pancreas
 Lung Antibodies  >2 publications with PDIA6 and Lung
 Bone Marrow Antibodies  >2 publications with PDIA6 and Bone Marrow
 Liver Antibodies  >2 publications with PDIA6 and Liver
 Cervix Antibodies  >1 publications with PDIA6 and Cervix
 Vascular Antibodies  >1 publications with PDIA6 and Vascular
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