Human PI4KB cDNA Clone Expression Plasmid – Cat# MBS1269636

PI4KB cDNA Clone – Phosphatidylinositol 4-Kinase, Catalytic, Beta (Human)

Name: PI4KB cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269636
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269636

MBS1269636 is a cDNA clone targeting PI4KB. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PI4KB, cDNA Clone

Full Product Name

PI4KB cDNA Clone

Product Gene Name

PI4KB cdna clone

Sequence

atgggagata cagtagtgga gcctgccccc ttgaagccaa cttctgagcc cacttctggc ccaccaggga ataatggggg gtccctgcta agtgtcatca cggagggggt cggggaacta tcagtgattg accctgaggt ggcccagaag gcctgccagg aggtgttgga gaaagtcaag cttttgcatg gaggcgtggc agtctctagc agaggcaccc cactggagtt ggtcaatggg gatggtgtgg acagtgagat ccgttgccta gatgatccac ctgcccagat cagggaggag gaagatgaga tgggggccgc tgtggcctca ggcacagcca aaggagcaag aagacggcgg cagaacaact cagctaaaca gtcttggctg ctgaggctgt ttgagtcaaa actgtttgac atctccatgg ccatttcata cctgtataac tccaaggagc ctggagtaca agcctacatt ggcaaccggc tcttctgctt tcgcaacgag gacgtggact tctatctgcc ccagttgctt aacatgtaca tccacatgga tgaggacgtg ggtgatgcca ttaagcccta catagtccac cgttgccgcc agagcattaa cttttccctc cagtgtgccc tgttgcttgg ggcctattct tcagacatgc acatttccac tcaacgacac tcccgtggga ccaagctacg gaagctgatc ctctcagatg agctaaagcc agctcacagg aagagggagc tgccctcctt gagcccggcc cctgatacag ggctgtctcc ctccaaaagg actcaccagc gctctaagtc agatgccact gccagcataa gtctcagcag caacctgaaa cgaacagcca gcaaccctaa agtggagaat gaggatgagc ctgttcgact ggctcctgag agagaattca tcaagtccct gatggcgatc ggcaagcggc tggccacgct ccccaccaaa gagcagaaaa cacagaggct gatctcagag ctctccctgc tcaaccataa gctccctgcc cgagtctggc tgcccactgc tggctttgac caccacgtgg tccgtgtacc ccacacacag gctgttgtcc tcaactccaa ggacaaggct ccctacctga tttatgtgga agtccttgaa tgtgaaaact ttgacaccac cagtgtccct gcccggatcc ccgagaaccg aattcggagt acgaggtccg tagaaaactt gcccgaatgt ggtattaccc atgagcagcg agctggcagc ttcagcactg tgcccaacta tgacaacgat gatgaggcct ggtcggtgga tgacataggc gagctgcaag tggagctccc cgaagtgcat accaacagct gtgacaacat ctcccagttc tctgtggaca gcatcaccag ccaggagagc aaggagcctg tgttcattgc agcaggggac atccgccggc gcctttcgga acagctggct cataccccga cagccttcaa acgagaccca gaagatcctt ctgcagttgc tctcaaagag ccctggcagg agaaagtacg gcggatcaga gagggctccc cctacggcca tctccccaat tggcggctcc tgtcagtcat tgtcaagtgt ggggatgacc ttcggcaaga gcttctggcc tttcaggtgt tgaagcaact gcagtccatt tgggaacagg agcgagtgcc cctttggatc aagccataca agattcttgt gatttcggct gatagtggca tgattgaacc agtggtcaat gctgtgtcca tccatcaggt gaagaaacag tcacagctct ccttgctcga ttacttccta caggagcacg gcagttacac cactgaggca ttcctcagtg cacagcgcaa ttttgtgcaa agttgtgctg ggtactgctt ggtctgctac ctgctgcaag tcaaggacag acacaatggg aatatccttt tggacgcaga aggccacatc atccacatcg actttggctt catcctctcc agctcacccc gaaatctggg ctttgagacg tcagccttta agctgaccac agagtttgtg gatgtgatgg gcggcctgga tggcgacatg ttcaactact ataagatgct gatgctgcaa gggctgattg ccgctcggaa acacatggac aaggtggtgc agatcgtgga gatcatgcag caaggttctc agcttccttg cttccatggc tccagcacca ttcgaaacct caaagagagg ttccacatga gcatgactga ggagcagctg cagctgctgg tggagcagat ggtggatggc agtatgcggt ctatcaccac caaactctat gacggcttcc agtacctcac caacggcatc atgtga

Molecular Weight

54,976 Da

OMIM

602758

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PI4KB cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PI4KB. It may not necessarily be applicable to this product.

NCBI GI #

33875124

NCBI GeneID

5298

NCBI Accession #

BC000029

UniProt Secondary Accession #

O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; B4DGI2

UniProt Related Accession #

Q9UBF8

NCBI Official Full Name

Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta, mRNA

NCBI Official Synonym Full Names

phosphatidylinositol 4-kinase beta

NCBI Official Symbol

PI4KB

NCBI Official Synonym Symbols

NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA

UniProt Protein Name

Phosphatidylinositol 4-kinase beta

UniProt Synonym Protein Names

NPIK; PI4K92

Protein Family

Phosphatidylinositol 4-kinase

UniProt Gene Name

PI4KB

UniProt Synonym Gene Names

PIK4CB; PI4K-beta; PI4Kbeta; PtdIns 4-kinase beta

UniProt Entry Name

PI4KB_HUMAN

NCBI Protein Information

phosphatidylinositol 4-kinase beta

UniProt Comments for PI4KB

PIK4CB: a member of the PI3/PI4 kinase family. Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-biphosphate (PIP2) on the Golgi complex. May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Three splice-variant isoforms have been described.

Protein type: Motility/polarity/chemotaxis; Kinase, lipid; Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.67

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; endosome; Golgi membrane

Molecular Function: 1-phosphatidylinositol 4-kinase activity; protein binding

Biological Process: phosphatidylinositol biosynthetic process; receptor-mediated endocytosis; signal transduction

Research Articles on PI4KB

1. PI4KIIIbeta likely plays a role in breast oncogenesis and that cooperation between Rab11a and PI4KIIIbeta represents a novel Akt activation pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PI4KB cdna clone

Products by Pathway	Pathway Diagram
3-phosphoinositide Biosynthesis Pathway antibodies	3-phosphoinositide Biosynthesis Pathway Diagram
3-phosphoinositide Biosynthesis Pathway antibodies	3-phosphoinositide Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies	Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies	Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
Integrins In Angiogenesis Pathway antibodies	Integrins In Angiogenesis Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with PI4KB cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>2 publications with PI4KB and Nervous System Diseases
Liver Diseases Antibodies	>1 publications with PI4KB and Liver Diseases

Organs/Tissues associated with PI4KB cdna clone

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with PI4KB and Bone
Liver Antibodies	>1 publications with PI4KB and Liver