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PIGC cDNA Clone – Phosphatidylinositol Glycan Anchor Biosynthesis, Class C (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278332

MBS1278332 is a cDNA clone targeting PIGC. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PIGC, cDNA Clone
Full Product Name
PIGC cDNA Clone
Product Gene Name
PIGC cdna clone
Sequence
atgtatgctc aacctgtgac taacaccaag gaggtcaagt ggcagaaggt cttgtatgag cgacagccct ttcctgataa ctatgtggac cggcgattcc tggaagagct ccggaaaaac atccatgctc ggaaatacca atattgggct gtggtatttg agtccagtgt ggtgatccag cagctgtgca gtgtttgtgt ttttgtggtt atctggtggt atatggatga gggtcttctg gccccccatt ggcttttagg gactggtctg gcttcttcac tgattgggta tgttttgttt gatctcattg atggaggtga agggcggaag aagagtgggc agacccggtg ggctgacctg aagagtgccc tagtcttcat tactttcact tatgggtttt caccagtgct gaagaccctt acagagtctg tcagcactga caccatctat gccatgtcag tcttcatgct gttaggccat ctcatctttt ttgactatgg tgccaatgct gccattgtat ccagcacact atccttgaac atggccatct ttgcttctgt atgcttggca tcacgtcttc cccggtccct gcatgccttc atcatggtga catttgccat tcagattttt gccctgtggc ccatgttgca gaagaaacta aaggcatgta ctccccggag ctatgtgggg gtcacactgc tttttgcatt ttcagccgtg ggaggcctac tgtccattag tgctgtggga gccgtactct ttgcccttct gctgatgtct atctcatgtc tgtgtccatt ctacctcatt cgcttgcagc tttttaaaga aaacattcat gggccttggg atgaagctga aatcaaggaa gacttgtcca ggttcctcag ttaa
Molecular Weight
33,583 Da
OMIM
601730
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PIGC cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PIGC. It may not necessarily be applicable to this product.

NCBI GI #
33869538
NCBI GeneID
5279
NCBI Accession #
BC006539
UniProt Secondary Accession #
O14491
UniProt Related Accession #
Q92535
NCBI Official Full Name
Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class C, mRNA
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis class C
NCBI Official Symbol
PIGC
NCBI Official Synonym Symbols
GPI2
UniProt Protein Name
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
UniProt Synonym Protein Names
Phosphatidylinositol-glycan biosynthesis class C protein; PIG-C
Protein Family
Phosphatidylinositol N-acetylglucosaminyltransferase
UniProt Gene Name
PIGC
UniProt Synonym Gene Names
GPI2; PIG-C
UniProt Entry Name
PIGC_HUMAN
NCBI Protein Information
phosphatidylinositol N-acetylglucosaminyltransferase subunit C

NCBI Summary for PIGC

This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008]
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UniProt Comments for PIGC

PIGC: Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Belongs to the PIGC family.

Protein type: EC 2.4.1.198; Endoplasmic reticulum; Transferase; Membrane protein, multi-pass; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23-q25

Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

Molecular Function: catalytic activity

Biological Process: GPI anchor biosynthetic process; preassembly of GPI anchor in ER membrane
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Research Articles on PIGC

1. Genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. Adipose tissue (AT) mRNA expression of 6 genes (TBX15/WARS2, STAB1, PIGC, ZNRF3, GRB14

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PIGC cdna clone

 Products by Pathway  Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway antibodies  Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway Diagram

Diseases associated with PIGC cdna clone

 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >3 publications with PIGC and Drug Toxicity
 Inflammation Antibodies  >2 publications with PIGC and Inflammation
 Liver Diseases Antibodies  >1 publications with PIGC and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with PIGC and Cardiovascular Diseases
 Kidney Diseases Antibodies  >1 publications with PIGC and Kidney Diseases

Organs/Tissues associated with PIGC cdna clone

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >2 publications with PIGC and Vascular
 Blood Antibodies  >2 publications with PIGC and Blood
 Adipose Tissue Antibodies  >2 publications with PIGC and Adipose Tissue
 Eye Antibodies  >1 publications with PIGC and Eye
 Kidney Antibodies  >1 publications with PIGC and Kidney
 Skin Antibodies  >1 publications with PIGC and Skin
 Connective Tissue Antibodies  >1 publications with PIGC and Connective Tissue
 Liver Antibodies  >1 publications with PIGC and Liver
 Lymph Antibodies  >1 publications with PIGC and Lymph
 Stomach Antibodies  >1 publications with PIGC and Stomach
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