Human PIGO cDNA Clone Expression Plasmid – Cat# MBS1272455

PIGO cDNA Clone – Phosphatidylinositol Glycan Anchor Biosynthesis, Class O (Human)

Name: PIGO cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272455
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272455

MBS1272455 is a cDNA clone targeting PIGO. More details

$550 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PIGO, cDNA Clone

Full Product Name

PIGO cDNA Clone

Product Gene Name

PIGO cdna clone

Sequence

atggacagtg gtgaatggga agtgagcaat cagcacgtcc tgggtgtgga ccactgtggt cacaagcatg gccctcacca ccctgaaatg gccaagaaac ttagccagat ggaccaggtg atccagggac ttgtggagcg tctggagaat gacacactgc tggtagtggc tggggaccat gggatgacca caaatggaga ccatggaggg gacagtgagc tggaggtctc agctgctctc tttctgtata gccccacagc agtcttcccc agcaccccac cagaggagcc agaggtgatt cctcaagtta gccttgtgcc cacgctggcc ctgctgctgg gcctgcccat cccatttggg aatatcgggg aagtgatggc tgagctattc tcagggggtg aggactccca gccccactcc tctgctttag cccaagcctc agctctccat ctcaatgctc agcaggtgtc ccgatttctt catacctact cagctgctac tcaggacctt caagctaagg agcttcatca gctgcagaac ctcttctcca aggcctctgc tgactaccag tggcttctcc agagccccaa gggggctgag gcgacactgc cgactgtgat tgctgagctg cagcagttcc tgcggggagc tcgggccatg tgcatcgagt cttgggctcg tttctctctg agcttccttc tcctacatct gcttgctgct gggatacccg tcaccacccc tggtcctttt actgtgccat ggcaggcagt ctcggcttgg gccctcatgg ccacacagac cttctactcc acaggccacc agcctgtctt tccagccatc cattggcatg cagccttcgt gggattccca gagggtcatg gctcctgtac ttggctgcct gctttgctag tgggagccaa cacctttgcc tcccacctcc tctttgcagt aggttgccca ctgctcctgc tctggccttt cctgtgtgag agtcaagggc tgcggaagag acagcagccc ccagggaatg aagctgatgc cagagtcaga cccgaggagg aagaggagcc actgatggag atgcggctcc gggatgcgcc tcagcacttc tatgcagcac tgctgcagct gggcctcaag tacctcttta tccttggtat tcagattctg gcctgtgcct tggcagcctc catccttcgc aggcatctca tggtctggaa agtgtttgcc cctaagttca tatttgaggc tgtgggcttc attgtgagca gcgtgggact tctcctgggc atagctttgg tgatgagagt ggatggtgct gtgagctcct ggttcaggca gctatttctg gcccagcaga ggtag

Molecular Weight

73,992 Da

OMIM

614730

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PIGO cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PIGO. It may not necessarily be applicable to this product.

NCBI GI #

38014614

NCBI GeneID

84720

NCBI Accession #

BC001030

UniProt Secondary Accession #

Q6P154; Q6UX80; Q8TDS8; Q96CS9; Q9BVN9; Q9Y4B0; B1AML3

UniProt Related Accession #

Q8TEQ8

NCBI Official Full Name

Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class O, mRNA

NCBI Official Synonym Full Names

phosphatidylinositol glycan anchor biosynthesis class O

NCBI Official Symbol

PIGO

NCBI Official Synonym Symbols

HPMRS2

UniProt Protein Name

GPI ethanolamine phosphate transferase 3

UniProt Synonym Protein Names

Phosphatidylinositol-glycan biosynthesis class O protein; PIG-O

UniProt Gene Name

PIGO

UniProt Synonym Gene Names

PIG-O

UniProt Entry Name

PIGO_HUMAN

NCBI Protein Information

GPI ethanolamine phosphate transferase 3

NCBI Summary for PIGO

This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

UniProt Comments for PIGO

PIGO: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transferase; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Endoplasmic reticulum; Membrane protein, integral; EC 2.-.-.-

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: endoplasmic reticulum membrane; membrane

Molecular Function: mannose-ethanolamine phosphotransferase activity

Biological Process: GPI anchor biosynthetic process

Disease: Hyperphosphatasia With Mental Retardation Syndrome 2

Research Articles on PIGO

1. Novel PIGO mutations expand the clinical spectrum of PIGO abnormalities to include epileptic encephalopathy with mild elevation of alkaline phosphatase (ALP).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PIGO cdna clone

Products by Pathway	Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies	Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway antibodies	Synthesis Of Glycosylphosphatidylinositol (GPI) Pathway Diagram

Diseases associated with PIGO cdna clone

Disease Name	Pubmed Publications
Hyperplasia Antibodies	>3 publications with PIGO and Hyperplasia
Carcinoma Antibodies	>2 publications with PIGO and Carcinoma
Weight Loss Antibodies	>2 publications with PIGO and Weight Loss
Inflammation Antibodies	>2 publications with PIGO and Inflammation
Precancerous Conditions Antibodies	>1 publications with PIGO and Precancerous Conditions
Body Weight Changes Antibodies	>1 publications with PIGO and Body Weight Changes
Insulin Resistance Antibodies	>1 publications with PIGO and Insulin Resistance
Neoplasms Antibodies	>1 publications with PIGO and Neoplasms
Blood Coagulation Disorders Antibodies	>1 publications with PIGO and Blood Coagulation Disorders
Fatty Liver Antibodies	>1 publications with PIGO and Fatty Liver

Organs/Tissues associated with PIGO cdna clone

Organ/Tissue Name	Pubmed Publications
Esophagus Antibodies	>2 publications with PIGO and Esophagus