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PLA2G12A cDNA Clone – Phospholipase A2, Group XIIA (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270683

MBS1270683 is a cDNA clone targeting PLA2G12A. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLA2G12A, cDNA Clone
Full Product Name
PLA2G12A cDNA Clone
Product Gene Name
Sequence
atggccctgc tctcgcgccc cgcgctcacc ctcctgctcc tcctcatggc cgctgttgtc aggtgccagg agcaggccca gaccaccgac tggagagcca ccctgaagac catccggaac ggcgttcata agatagacac gtacctgaac gccgccttgg acctcctggg aggcgaggac ggtctctgcc agtataaatg cagtgacgga tctaagcctt tcccacgtta tggttataaa ccctccccac cgaatggatg tggctctcca ctgtttggtg ttcatcttaa cattggtatc ccttccctga caaagtgttg caaccaacac gacaggtgct atgagacctg tggcaaaagc aagaatgact gtgatgaaga attccagtat tgcctctcca agatctgccg agatgtacag aaaacactag gactaactca gcatgttcag gcatgtgaaa caacagtgga gctcttgttt gacagtgtta tacatttagg ttgtaaacca tatctggaca gccaacgagc cgcatgcagg tgtcattatg aagaaaaaac tgatctttaa
Molecular Weight
21,067 Da
OMIM
611652
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PLA2G12A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G12A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens phospholipase A2, group XIIA, mRNA
NCBI Official Synonym Full Names
phospholipase A2 group XIIA
NCBI Official Symbol
PLA2G12A
NCBI Official Synonym Symbols
GXII; ROSSY; PLA2G12
UniProt Protein Name
Group XIIA secretory phospholipase A2
UniProt Synonym Protein Names
Phosphatidylcholine 2-acylhydrolase 12A
UniProt Gene Name
PLA2G12A
UniProt Synonym Gene Names
PLA2G12; GXII sPLA2; sPLA2-XII
UniProt Entry Name
PG12A_HUMAN
NCBI Protein Information
group XIIA secretory phospholipase A2

NCBI Summary for PLA2G12A

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008]
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UniProt Comments for PLA2G12A

PLA2G12A: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine. Belongs to the phospholipase A2 family.

Protein type: Secreted, signal peptide; EC 3.1.1.4; Lipid Metabolism - ether lipid; Secreted; Lipid Metabolism - linoleic acid; Lipid Metabolism - glycerophospholipid; Endoplasmic reticulum; Lipid Metabolism - arachidonic acid; Phospholipase; Lipid Metabolism - alpha-linolenic acid

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: extracellular region

Molecular Function: phospholipase A2 activity

Biological Process: phosphatidic acid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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