Human PLCD4 cDNA Clone Expression Plasmid – Cat# MBS1272140

PLCD4 cDNA Clone – Phospholipase C, Delta 4 (Human)

Name: PLCD4 cDNA Clone; Phospholipase C, Delta 4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272140
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272140

MBS1272140 is a cDNA clone targeting PLCD4. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLCD4, cDNA Clone

Full Product Name

PLCD4 cDNA Clone

Product Gene Name

PLCD4 cdna clone

Sequence

atggcgtccc tgctgcaaga ccagctgacc actgatcagg acttgctgct gatgcaggaa ggcatgccga tgcgcaaggt gaggtccaaa agctggaaga agctaagata cttcagactt cagaatgacg gcatgacagt ctggcatgca cggcaggcca ggggcagtgc caagcccagc ttctcaatct ctgatgtgga gacaatacgt aatggccatg attccgagtt gctgcgtagc ctggcagagg agctccccct ggagcagggc ttcaccattg tcttccatgg ccgccgctcc aacctggacc tgatggccaa cagtgttgag gaggcccaga tatggatgcg agggctccag ctgttggtgg atcttgtcac cagcatggac catcaggagc gcctggacca atggctgagc gattggtttc aacgtggaga caaaaatcag gatggtaaga tgagtttcca agaagttcag cggttattgc acctaatgaa tgtggaaatg gaccaagaat atgccttcag tctttttcag gcagcagaca cgtcccagtc tggaaccctg gaaggagaag aattcgtaca gttctataag gcattgacta aacgtgctga ggtgcaggaa ctgtttgaaa gtttttcagc tgatgggcag aagctgactc tgctggaatt tttggatttc ctccaagagg agcagaagga gagagactgc acctctgagc ttgctctgga actcattgac cgctatgaac cttcagacag tggcaaactg cggcatgtgc tgagtatgga tggcttcctc agctacctct gctctaagga tggagacatc ttcaacccag cctgcctccc catctatcag gatatgactc aacccctgaa ccactacttc atctgctctt ctcataacac ctacctagtg ggggaccagc tttgcggcca gagcagcgtc gagggatata tacgggccct gaagcggggg tgccgctgcg tggaggtgga tgtatgggat ggacctagcg gggaacctgt cgtttaccac ggacacaccc tgacctcccg catcctgttc aaagatgtcg tggccacagt agcacagtat gccttccaga catcagacta cccagtcatc ttgtccctgg agacccactg cagctgggag cagcagcaga ccatggcccg tcatctgact gagatcctgg gggagcagct gctgagcacc accttggatg gggtgctgcc cactcagctg ccctcgcctg aggagcttcg gaggaagatc ctggtgaagg ggaagaagtt aacacttgag gaagacctgg aatatgagga agaggaagca gaacctgagt tggaagagtc agaattggcg ctggagtccc agtttgagac tgagcctgag ccccaggagc agaaccttca gaataaggac aaaaagaaga aatccaagcc catcttgtgt ccagccctct cttccctggt tatctacttg aagtctgtct cattccgcag cttcacacat tcaaaggagc actaccactt ctacgagata tcatctttct ctgaaaccaa ggccaagcgc ctcatcaagg aggctggcaa tgagtttgtg cagcacaata cttggcagtt aagccgtgtg tatcccagcg gcctgaggac agactcttcc aactacaacc cccaggaact ctggaatgca ggctgccaga tggtggccat gaatatgcag actgcagggc ttgaaatgga catctgtgat gggcatttcc gccagaatgg cggctgtggc tatgtgctga agccagactt cctgcgtgat atccagagtt ctttccaccc tgagaagccc atcagccctt tcaaagccca gactctctta atccaggtga tcagcggtca gcaactcccc aaagtggaca agaccaaaga ggggtccatt gtggatccac tggtgaaagt gcagatcttt ggcgttcgtc tagacacagc acggcaggag accaactatg tggagaacaa tggttttaat ccatactggg ggcagacact atgtttccgg gtgctggtgc ctgaacttgc catgctgcgt tttgtggtaa tggattatga ctggaaatcc cgaaatgact ttattggtca gtacaccctg ccttggacct gcatgcaaca aggttaccgc cacattcacc tgctgtccaa agatggcatc agcctccgcc cagcttccat ctttgtgtat atctgcatcc aggaaggcct ggagggggat gagtcctga

Molecular Weight

31,448 Da

OMIM

605939

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PLCD4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLCD4. It may not necessarily be applicable to this product.

NCBI GI #

33871718

NCBI GeneID

84812

NCBI Accession #

BC006355

UniProt Secondary Accession #

Q53FS8

UniProt Related Accession #

Q9BRC7

NCBI Official Full Name

Homo sapiens phospholipase C, delta 4, mRNA

NCBI Official Synonym Full Names

phospholipase C delta 4

NCBI Official Symbol

PLCD4

UniProt Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

UniProt Synonym Protein Names

Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4

Protein Family

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

UniProt Gene Name

PLCD4

UniProt Synonym Gene Names

hPLCD4; PLC-delta-4

UniProt Entry Name

PLCD4_HUMAN

NCBI Protein Information

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

NCBI Summary for PLCD4

This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer. [provided by RefSeq, Jan 2011]

UniProt Comments for PLCD4

PLCD4: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida- induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.11; Phospholipase; Carbohydrate Metabolism - inositol phosphate

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cytoplasm; nuclear membrane; plasma membrane

Research Articles on PLCD4

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PLCD4 cdna clone

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies	D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
D-myo-inositol-5-phosphate Metabolism Pathway antibodies	D-myo-inositol-5-phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies	Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies	Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
Phosphatidylinositol Signaling System Pathway antibodies	Phosphatidylinositol Signaling System Pathway Diagram
Phosphatidylinositol Signaling System Pathway antibodies	Phosphatidylinositol Signaling System Pathway Diagram

Organs/Tissues associated with PLCD4 cdna clone

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>3 publications with PLCD4 and Testis
Liver Antibodies	>2 publications with PLCD4 and Liver
Embryonic Tissue Antibodies	>1 publications with PLCD4 and Embryonic Tissue
Brain Antibodies	>1 publications with PLCD4 and Brain