Human PLEKHA8 cDNA Clone Expression Plasmid – Cat# MBS1278994

PLEKHA8 cDNA Clone – Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (Human)

Name: PLEKHA8 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278994
Price: 555 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278994

MBS1278994 is a cDNA clone targeting PLEKHA8. More details

$555 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLEKHA8, cDNA Clone

Full Product Name

PLEKHA8 cDNA Clone

Product Gene Name

PLEKHA8 cdna clone

Sequence

atggaggggg tgctgtacaa gtggaccaac tatctgagcg gttggcagcc tcgatggttc cttctctgtg ggggaatatt gtcctattat gattctcctg aagatgcctg gaaaggttgc aaagggagca tacaaatggc agtctgtgaa attcaagttc attctgtaga taatacacgc atggacctga taatccctgg ggaacagtat ttctacctga aggccagaag tgtggctgaa agacagcggt ggctggtggc cctgggatca gccaaggctt gcctgactga cagtaggacc cagaaggaga aagagtttgc tgaaaacact gaaaacttga aaaccaaaat gtcagaacta agactctact gtgacctcct tgttcagcaa gtagataaaa caaaagaagt gaccacaact ggtgtgtcca attctgagga gggaattgat gtgggaactt tgctgaaatc aacctgtaat acttttctga agaccttgga agaatgcatg cagatcgcaa atgcagcctt cacctctgag ctgctctacc gcactccacc aggatcacct cagctggcca tgctcaagtc cagcaagatg aaacatccta ttataccaat tcataattca ttggaaaggc aaatggagtt gagcacttgt gaaaatggat ctttaaatat ggaaataaat ggtgaggaag aaatcctaat gaaaaataag aattccttat atttgaaatc tgcagagata gactgcagca tatcaagtga ggaaaataca gatgataata taacagtcca aggtgaaata aggaaggaag atggaatgga aaacctgaaa aatcatgaca ataacttgac tcagtctgga tcagactcaa gttgctctcc ggaatgcctc tgggaggaag gcaaagaagt tatcccaact ttctttagta ccatgaacac aagctttagt gacattgaac ttctggaaga cagtggcatt cccacagaag cattcttggc atcatgttat gctgtggttc cagtattaga caaacttggc cctacagtgt ttgctcctgt taagatggat cttgttggaa atattaagaa agtaaatcag aagtatataa ccaacaaaga agagtttacc actctccaga agatagtgct gcacgaagtg gaggcggatg tagcccaggt taggaactca gcgactgaag ccctcttgtg gctgaagaga ggtctcaaat ttttgaaggg atttttgaca gaagtgaaaa atggggagaa ggatatccag acagccctaa ataatgcata tggtaaaaca ttgcggcaac accatggctg ggtagttcga ggggtttttg cggtgtag

Molecular Weight

49,462 Da

OMIM

608639

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PLEKHA8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLEKHA8. It may not necessarily be applicable to this product.

NCBI GI #

32449732

NCBI GeneID

84725

NCBI Accession #

BC053990

UniProt Secondary Accession #

Q7Z5V8; Q9BU78; Q9H274; Q9H8Z7; B4DH00

UniProt Related Accession #

Q96JA3

NCBI Official Full Name

Homo sapiens pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8, mRNA

NCBI Official Synonym Full Names

pleckstrin homology domain containing A8

NCBI Official Symbol

PLEKHA8

NCBI Official Synonym Symbols

FAPP2

UniProt Protein Name

Pleckstrin homology domain-containing family A member 8

UniProt Synonym Protein Names

Phosphatidylinositol-four-phosphate adapter protein 2; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2; Serologically defined breast cancer antigen NY-BR-86

Protein Family

Pleckstrin homology domain-containing family

UniProt Gene Name

PLEKHA8

UniProt Synonym Gene Names

FAPP2; PH domain-containing family A member 8; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2

UniProt Entry Name

PKHA8_HUMAN

NCBI Protein Information

pleckstrin homology domain-containing family A member 8

UniProt Comments for PLEKHA8

PLEKHA8: Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: trans-Golgi network

Molecular Function: glycolipid binding; glycolipid transporter activity

Biological Process: lipid transport

Research Articles on PLEKHA8

1. Altogether, this study implies that hepatitis C virus coopts FAPP2 for virus genome replication via phosphatidylinositol 4-phosphate binding and glycosphingolipid transport to the hepatitis C virus replication complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PLEKHA8 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with PLEKHA8 and Neoplasms
Nervous System Diseases Antibodies	>1 publications with PLEKHA8 and Nervous System Diseases