Human PPP2R1B cDNA Clone Expression Plasmid – Cat# MBS1272696

PPP2R1B cDNA Clone – Protein Phosphatase 2 (Formerly 2a), Regulatory Subunit A, Beta Isoform (Human)

Name: PPP2R1B cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272696
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272696

MBS1272696 is a cDNA clone targeting PPP2R1B. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PPP2R1B, cDNA Clone

Full Product Name

PPP2R1B cDNA Clone

Product Gene Name

PPP2R1B cdna clone

Sequence

atggcgggcg catcagagct cgggaccggc ccaggagcag cgggtggaga tggagatgat tcgctatacc cgatcgcggt tttaatcgac gagctccgca atgaagacgt gcagctccga ctcaacagta ttaagaagtt atcaacaatt gccctagcac ttggagtaga aaggacccga agtgaattgt tgccatttct tacagataca atttatgatg aagatgaggt actattagct cttgctgagc agctgggaaa tttcactggc ctagtgggag gtcctgactt tgcccactgt ctgctgcctc ctttggaaaa tctggcaact gtggaagaga ctgttgttcg tgacaaggct gtggagtccc tgagacagat ctcccaggag catactcctg ttgctctgga agcttatttt gtacctctgg tgaaacgctt agcaagtggg gattggttca cctctcgcac atctgcatgt ggtttgttca gcgtttgcta tcccagggca tcaaatgctg ttaaagcaga aatcagacag caattccgtt ccttgtgctc agatgacaca ccaatggtac gacgtgctgc tgcttccaaa ttgggtgaat ttgcaaaagt tttggaatta gacagtgtga aaagtgaaat tgttccactg ttcactagtc tagcttcaga tgaacaggat tcagtgcgcc tccttgctgt ggaagcttgt gtcagtattg cccagttatt gtctcaggat gaccttgaga ctttggtgat gcctacactt cgacaagcag cagaagataa atcttggcgc gttcgctata tggtggctga cagattttca gagctccaga aagccatggg tcctaaaatc accctaaatg acctcatccc cgcctttcag aacctactta aagactgtga agctgaagtc cgggctgctg ctgcccacaa agtaaaagaa cttggtgaga acttgcccat tgaagataga gagaccataa ttatgaatca aattctgcct tatataaagg aattagtatc cgataccaat caacatgtca aatcggctct agcttctgta attatgggat tgtctactat tttgggcaaa gaaaatacca ttgaacatct tctacctctt ttcttagctc agttaaagga tgagtgtcct gacgttcgtt tgaatatcat ctccaatttg gattgtgtaa atgaagtgat tggaatccgt cagctctctc agtctctcct tcctgccata gtggagctgg cagaagatgc caaatggagg gtccgcctgg ccatcattga gtatatgccg ctgctggcag gccagctggg tgtggaattc tttgatgaaa agctgaattc tttatgtatg gcttggctcg tggaccatgt atacgccatc cgagaagctg ccaccaacaa cctcatgaaa ctagttcaga agtttggtac agagtgggcc caaaatacta ttgttcccaa agtgttagta atggcaaatg atcctaatta cttgcataga atgaccactt tattctgcat taatgcactg tctgaggcct gtggtcagga aataactact aagcaaatgc tgcccatcgt attaaaaatg gcaggagacc aagtagcaaa tgttcgcttc aatgtggcca aatctctaca aaagattgga ccaattctag ataccaatgc tttacaggga gaagtgaagc cagtactaca gaagttaggt caagatgaag acatggatgt caaatacttt gcacaggaag ctataagtgt ggtggcacaa aggctgagga agctagaatt tcctgtgaag gacagtggag aacccagtgt ccctcgggct gacaagaacc acttcccaag acccacagtg cctggagagg acatggggaa gggaccagtg tatcagttgc gtggagatac tagagacaca cttgcccagc tgggaattgc agagctagtg catttctccc aaagcacaga ctaa

Molecular Weight

52,214 Da

OMIM

603113

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PPP2R1B cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP2R1B. It may not necessarily be applicable to this product.

NCBI GI #

34783402

NCBI GeneID

5519

NCBI Accession #

BC027596

UniProt Secondary Accession #

O75620; Q8NHV8; A8MY67; B0YJ69; B4DGQ6; B4DK91; B4DWW5; F8W8G1

UniProt Related Accession #

P30154

NCBI Official Full Name

Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform, mRNA

NCBI Official Synonym Full Names

protein phosphatase 2 scaffold subunit Abeta

NCBI Official Symbol

PPP2R1B

NCBI Official Synonym Symbols

PR65B; PP2A-Abeta

UniProt Protein Name

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

UniProt Synonym Protein Names

PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta

UniProt Gene Name

PPP2R1B

UniProt Entry Name

2AAB_HUMAN

NCBI Protein Information

serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

NCBI Summary for PPP2R1B

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

UniProt Comments for PPP2R1B

PPP2R1B: The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Belongs to the phosphatase 2A regulatory subunit A family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: lipid raft

Molecular Function: protein binding

Disease: Lung Cancer

Research Articles on PPP2R1B

1. MicroRNA-587 antagonizes 5-fluorouracil-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PPP2R1B cdna clone

Products by Pathway	Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Beta-catenin Phosphorylation Cascade Pathway antibodies	Beta-catenin Phosphorylation Cascade Pathway Diagram
CTLA4 Inhibitory Signaling Pathway antibodies	CTLA4 Inhibitory Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Costimulation By The CD28 Family Pathway antibodies	Costimulation By The CD28 Family Pathway Diagram
Cyclin D Associated Events In G1 Pathway antibodies	Cyclin D Associated Events In G1 Pathway Diagram

Diseases associated with PPP2R1B cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>39 publications with PPP2R1B and Neoplasms
Lung Neoplasms Antibodies	>12 publications with PPP2R1B and Lung Neoplasms
Breast Neoplasms Antibodies	>6 publications with PPP2R1B and Breast Neoplasms
Adenocarcinoma Antibodies	>4 publications with PPP2R1B and Adenocarcinoma
Cell Transformation, Neoplastic Antibodies	>3 publications with PPP2R1B and Cell Transformation, Neoplastic
Carcinoma, Hepatocellular Antibodies	>3 publications with PPP2R1B and Carcinoma, Hepatocellular
Brain Diseases Antibodies	>2 publications with PPP2R1B and Brain Diseases
Liver Neoplasms Antibodies	>1 publications with PPP2R1B and Liver Neoplasms
Drug Toxicity Antibodies	>1 publications with PPP2R1B and Drug Toxicity
Kidney Diseases Antibodies	>1 publications with PPP2R1B and Kidney Diseases

Organs/Tissues associated with PPP2R1B cdna clone

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>17 publications with PPP2R1B and Lung
Liver Antibodies	>5 publications with PPP2R1B and Liver
Brain Antibodies	>5 publications with PPP2R1B and Brain
Blood Antibodies	>3 publications with PPP2R1B and Blood
Ovary Antibodies	>3 publications with PPP2R1B and Ovary
Heart Antibodies	>3 publications with PPP2R1B and Heart
Skin Antibodies	>2 publications with PPP2R1B and Skin
Stomach Antibodies	>2 publications with PPP2R1B and Stomach
Vascular Antibodies	>2 publications with PPP2R1B and Vascular
Prostate Antibodies	>2 publications with PPP2R1B and Prostate